ChemicalBook--->CAS DataBase List--->72528-40-6

72528-40-6

72528-40-6 Structure

72528-40-6 Structure
IdentificationBack Directory
[Name]

Phenylglycylcefalexin
[CAS]

72528-40-6
[Synonyms]

Cefalexin Impurity
Cefalexin impurity C
Phenylglycylcefalexin
Cephalexin EP Impurity
Cefalexin EP Impurity C
Cephalexin EP Impurity C
D-Phenylglycyl Cephalexin
Cefalexin Impurity 3(EP Impurity C)
Cefalexin (Cephalexin) EP Impurity C
Cefalexin Impurity 3(Cefalexin EP Impurity C)
Phenylglycyl Cephalexin (Mixture of diastereoMers)
Cefalexin EP Impurity C?(D-Phenylglycyl Cephalexin)
(6R-trans)-D-2-Phenylglycyl-N-(2-carboxy-3-Methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-7-yl)-D-2-phenylglycinaMide
Glycinamide, D-2-phenylglycyl-N-(2-carboxy-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-7-yl)-D-2-phenyl-, (6R-trans)- (9CI)
(6R,7R)-7-[[(2R)-2-[[(2R)-2-Amino-2-phenylacetyl]amino]-2-phenylacetyl] amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Cephalexin EP Impurity C/(6R,7R)-7-((R)-2-((R)-2-amino-2-phenylacetamido)-2-phenylacetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Cefadroxil EP Impurity C:(6R,7R)-7-[[(2R)-2-[[(2R)-2-amino-2-phenylacetyl]amino]-2-phenylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
[Molecular Formula]

C24H24N4O5S
[MDL Number]

MFCD21363516
[MOL File]

72528-40-6.mol
[Molecular Weight]

480.536
Chemical PropertiesBack Directory
[Melting point ]

>207°C (dec.)
[storage temp. ]

-20°C Freezer, Under inert atmosphere
[solubility ]

Aqueous Acid (Slightly, Sonicated, Heated), DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[color ]

Off-White to Pale Beige
[InChIKey]

DMRMXTUJVSARRA-BXKYNXKVNA-N
[SMILES]

C(NC(=O)[C@H](C1=CC=CC=C1)N)(=O)[C@H](C1=CC=CC=C1)N[C@@H]1C(=O)N2[C@]1([H])SCC(C)=C2C(O)=O |&1:4,13,21,25,r|
Hazard InformationBack Directory
[Uses]

D-Phenylglycyl Cephalexin is an impurity of Cephalexin (C256800).
[Synthesis]

N-BOC-o-phenylglycine (753 mg, 3 mmol) was dissolved in a mixture of tetrahydrofuran (THF) (15 ml), Et3N 0.42 ml (3 mmol), and 3 drops of N-methylmorpholine, and stirred for 10 min at -15 °C. Isobutyl chloroformate (0.41 ml, 3 mmol) in 2 ml of THF was add
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