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7720-39-0

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7720-39-0 Structure

7720-39-0 Structure
IdentificationMore
[Name]

2-Aminoimidazole
[CAS]

7720-39-0
[Synonyms]

1H-IMIDAZOL-2-AMINE
2-AMINOIMIDAZOLE
2-Amino-1H-Imidazole
[EINECS(EC#)]

231-751-4
[Molecular Formula]

C3H5N3
[MDL Number]

MFCD00792530
[Molecular Weight]

83.09
[MOL File]

7720-39-0.mol
Chemical PropertiesBack Directory
[Boiling point ]

313.1±25.0 °C(Predicted)
[density ]

1.313±0.06 g/cm3(Predicted)
[storage temp. ]

Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
[form ]

solid
[pka]

15.06±0.10(Predicted)
[color ]

Brown
[CAS DataBase Reference]

7720-39-0(CAS DataBase Reference)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P305+P351+P338-P362+P364-P302+P352
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

26-37/39
[HS Code ]

2933299090
Raw materials And Preparation ProductsBack Directory
[Raw materials]

2,2-Diethoxyethylamine-->O-Methylisourea hemisulfate-->Carbamimidothioic acid-->2-Nitroimidazole-->sodium:cyanide-->Cyanamide-->imidazol-2-ylamine sulphate-->o-methylisourea-->3-Nitrobenzaldehyde-->GLYCOLALDEHYDE-->Aminoacetaldehyde dimethyl acetal-->Aminoacetonitrile-->Acetoacetamide
[Preparation Products]

Oxazole-2-amine-->ethyl 5-oxo-1,5-dihydroiMidazo[1,2-a]pyriMidine-6-carboxylate-->1-Phenyl-1H-iMidazol-2-aMine
Hazard InformationBack Directory
[Uses]

2-Aminoimidazole is a potent antibiofilm agent that can be used as an adjuvant to antimicrobial. 2-aminoimidazoles disrupts the ability of bacteria to protect themselves by inhibiting biofilm formation and genetically-encoded antibiotic resistance traits. 2-Aminoimidazole is also a weak noncompetitive inhibitor of human arginase I with a Ki of 3.6 mM.
[in vivo]

The 2-aminoimidazole analogs A1P (80 μg/g, Nebulization, Once in total) can reduce airways hyperresponsiveness to methacholine in an acute (3-week) ovalbumin (OVA)-sensitization and -challenge murine model[3].

Animal Model:Female Balb/C mice (6 - 8 weeks old) [Acute (3-week) ovalbumin (OVA)-sensitization and -challenge murine model][3]
Dosage:80 μg/g, Once in total
Administration:Nebulization
Result:The 2-aminoimidazole analogs A1P attenuated significantly the total resistance of the respiratory system (R) and the maximum resistance of the central airways (RN) following methacholine challenge.
[storage]

4°C, protect from light
Spectrum DetailBack Directory
[Spectrum Detail]

2-Aminoimidazole(7720-39-0)1HNMR
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