| Identification | More | [Name]
Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate | [CAS]
82692-93-1 | [Synonyms]
3-(N-ETHYL-3-METHYLANILINO)-2-HYDROXYPROPANESULFONIC ACID SODIUM SALT
3-(N-ETHYL-M-TOLUIDINO)-2-HYDROXYPROPANE-SULFONIC ACID SODIUM SALT
N-ETHYL-N-(2-HYDROXY-3-SULFOPROPYL)-3-TOLUIDINE SODIUM SALT
N-ETHYL-N-(2-HYDROXY-3-SULFOPROPYL)-M-TOLUIDINE SODIUM SALT
N-ETHYL-N-SULFOHYDROXYPROPYL-M-TOLUIDINE SODIUM SALT
N-ETHYL-N-SULPHOHYDROXYPROPYL-M-TOLUIDINE, SODIUM SALT
SODIUM 3-(N-ETHYL-3-METHYLANILINO)-2-HYDROXYPROPANESULFONATE
SODIUM N-ETHYL-N-(2-HYDROXY-3-SULFOPROPYL)-M-TOLUIDINE
TOOS
TOOS, SODIUM SALT
3-(n-ethyl-3-methylanilino)-2-hydroxypropansulf.acidso-salt
3-[ethyl(3-methylphenyl)amino]-2-hydroxy-1-propanesulfonicacimonosodiums
N-Ethyl-N-(2-hydroxy-3-sulfopropyl)-3-methylaniline sodium salt
Peroxidase/Hydrogen Peroxide Detection , Colorimetry
Trinder Reagent
N-ETHYL-N-(2-HYDROXY-3-SULFOPROPYL)-*M-T OLUIDINE SO
N-ETHYL-N-(2-HYDROXY-3-SULFOPROPYL)-3-METHYLANILINE
N-Ethyl-N-(2-hydroxy-3-sulfopropyl)-3-methylaniline,sodiumsalt,dihydrate
3-(N-ETHYL-3-METHYLANILINO)-2-HYDROXYPROPANSULF.ACIDSODIUMSALT
SODIUM 3-(N-ETHYL-3-METHYLANILINO)-2-HYDROXYPROPANESULFONATE TOOS | [EINECS(EC#)]
617-377-8 | [Molecular Formula]
C12H18NNaO4S | [MDL Number]
MFCD00040641 | [Molecular Weight]
295.33 | [MOL File]
82692-93-1.mol |
| Chemical Properties | Back Directory | [Appearance]
White crystalline powder | [storage temp. ]
Store at 0-5°C in dry and dark place. | [form ]
neat | [color ]
White to Almost white | [Detection Methods]
HPLC,NMR | [BRN ]
5689521 | [InChI]
InChI=1S/C12H19NO4S.Na.H/c1-3-13(8-12(14)9-18(15,16)17)11-6-4-5-10(2)7-11;;/h4-7,12,14H,3,8-9H2,1-2H3,(H,15,16,17);; | [InChIKey]
IRQRBVOQGUPTLG-UHFFFAOYSA-M | [SMILES]
N(C1C=CC=C(C)C=1)(CC)CC(O)CS(O)(=O)=O.[NaH] | [CAS DataBase Reference]
82692-93-1(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [F ]
3 | [HS Code ]
29214200 |
| Hazard Information | Back Directory | [Description]
Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate is a water-soluble reagent used in the enzymatic photometric determination of hydrogen peroxide. This compound is a widely studied small molecule inhibitor in scientific research. Originally synthesized in the early 1980s, it has since found extensive use in various investigations into cellular processes. It has its inhibition of the Na+/H+ exchanger (NHE), which is a membrane protein crucial for regulating intracellular pH. Additionally, EIPA has shown its potential as an inhibitor of TRPV channels, which play a role in pain sensation and thermoregulation. Another significant finding indicates Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate′s inhibition of the Na+/Ca2+ exchanger (NCX), responsible for regulating intracellular calcium levels.
| [Chemical Properties]
White crystalline powder | [Uses]
TOOS (TOOS sodium salt) is a highly water-soluble aniline derivative widely used in diagnostics and biological experiments. TOOS can be combined with 3-methyl-2-benzothiazolinone hydrazone hydrochloride (MBTH) to form a chromogenic system to measure oxidase activity. In the MBTH-TOOS chromogenic system, MBTH is catalytically oxidized to produce (-NH) free radicals, which react with TOOS to form colorless compounds. Furthermore, the colorless compound undergoes a disproportionation reaction to produce a blue-violet quinoid compound[1]. | [References]
[1] Lin X, et al. Boosting the oxidase-like activity of platinum nanozyme in MBTH-TOOS chromogenic system for detection of trypsin and its inhibitor. Talanta. 2021 Nov 1;234:122647. DOI:10.1016/j.talanta.2021.122647 |
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