Identification | Back Directory | [Name]
H2N-PEG4-CH2COOtBu | [CAS]
864680-64-8 | [Synonyms]
NH2-PEG4-CH2COOtB Amino-PEG4-C1-Boc NH2-PEG4-CH2COOtBu H2N-PEG4-CH2COOtBu Amino-PEG4-CH2CO2tBu Amino-PEG4-t-butyl acetate Amino-PEG4-CH2COOH t-Bu Ester tert-Butyl 14-amino-3,6,9,12-tetraoxatetradecanoate tert-butyl14-amino-3,6,9,12-tetraoxatetradecan-1-oate tert-Butyl 14-Amino-3,6,9,12-tetraoxa-1-tetradecanoate tert-butyl 2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]acetate 3,6,9,12-Tetraoxatetradecanoic acid, 14-amino-, 1,1-dimethylethylester H2N-PEG4-CH2COOtBu/3,6,9,12-Tetraoxatetradecanoic acid, 14-amino-, 1,1-dimethylethyl ester | [Molecular Formula]
C14H29NO6 | [MDL Number]
MFCD28122943 | [MOL File]
864680-64-8.mol | [Molecular Weight]
307.38 |
Chemical Properties | Back Directory | [Boiling point ]
386.1±32.0 °C(Predicted) | [density ]
1.051±0.06 g/cm3(Predicted) | [solubility ]
DMSO: 20 mg/mL (65.07 mM) | [form ]
Liquid | [pka]
8.74±0.10(Predicted) | [color ]
Colorless to light yellow | [Water Solubility ]
Water: 50 mg/mL (162.67 mM) |
Hazard Information | Back Directory | [Uses]
Amino-PEG4-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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