| Identification | Back Directory | [Name]
CMPD101 | [CAS]
865608-11-3 | [Synonyms]
CMPD101
Takeda101
3-[[[4-Methyl-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]methyl]amino]-N-[[2-(trifluoromethyl)phenyl]methyl]benzamide
Benzamide, 3-[[[4-methyl-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]methyl]amino]-N-[[2-(trifluoromethyl)phenyl]methyl]- | [Molecular Formula]
C24H21F3N6O | [MDL Number]
MFCD30182336 | [MOL File]
865608-11-3.mol | [Molecular Weight]
466.46 |
| Chemical Properties | Back Directory | [Melting point ]
>80°C (dec.) | [storage temp. ]
-20°C Freezer | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
Off-White to Pale Yellow |
| Hazard Information | Back Directory | [Uses]
CMPD101 is a potent and selective GRK2/3 inhibitor. | [IC 50]
GRK2: 18 nM (IC50); GRK3: 5.4 nM (IC50); PKCα: 8.1 μM (IC50); ROCK2: 1.4 μM (IC50) | [storage]
-20°C |
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