| Identification | More | [Name]
Tropisetron | [CAS]
89565-68-4 | [Synonyms]
BETA-TROPISETRON
TROPISETRON
8-methyl-8-azabicyclo(3.2.1)oct-3-ylester,endo-1h-indole-3-carboxylicaci
icf205-930
3-TROPANYL-INDOLE-3-CARBOXYLATE HYDROCHL ORIDE(ICS-205,930, NOVOBAN
3-TROPANYL-INDOLE-3-CARBOXYLATE METHIODI DE ICS-205,930, METHIODI
TROPISHTRON HYDROCHLORIDE
SS-TROPISETRON
1H-INDOLE-3-CARBOXYLIC ACID, (3-ENDO)-8-METHYL-8-AZABICYCLO [3,2,1]OCT-3-YL ESTER
8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, endo-1h-indole-3-carboxylic acid
3-Tropanylindole-3-carboxylate
TROPICACID
Indole-3-carbonyl chloride
lαH，5Αh-Tropan-3α-yl indole-3-carboxylate
1H-Indole-3-carboxylic acid (1β,5β)-8-methyl-8-azabicyclo[3.2.1]octan-3α-yl ester | [EINECS(EC#)]
1806241-263-5 | [Molecular Formula]
C17H20N2O2 | [MDL Number]
MFCD00864399 | [Molecular Weight]
284.35 | [MOL File]
89565-68-4.mol |
| Chemical Properties | Back Directory | [Melting point ]
201-202 °C | [Boiling point ]
448.5±35.0 °C(Predicted) | [density ]
1.26 | [storage temp. ]
2-8°C
| [solubility ]
H2O: soluble
| [form ]
solid
| [pka]
15.38±0.30(Predicted) | [color ]
white
| [Uses]
A substance that is used to prevent nausea and
vomiting caused by chemotherapy. | [CAS DataBase Reference]
89565-68-4(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Description]
Tropisetron is the third selective 5HT3-antagonist, after ondansetron and granisetron, to
be introduced for the management of nausea and vomiting induced by cancer
chemotherapy. Similar to the other two 5HT3-antagonists, vopisetron is superior to
metoclopramide. The compound has also been reported to have antiarrhythmic
activity. | [Chemical Properties]
Crystallized, melting point 201-202°C (dichloromethane-ethyl acetate). Tropisetron Monohydroehloride: C17H20N2O2-HCl. [105826-92-4]. Melting point 283-285°C (decomposition). | [Originator]
Sandoz (Switzerland) | [Definition]
ChEBI: An indolyl carboxylate ester obtained by formal condensation of the carboxy group of indole-3-carboxylic acid with the hydroxy group of tropine. | [Brand name]
Novaban | [Hazard]
Human systemic effects. |
|
| Company Name: |
China Langchem Inc.
|
| Telephone: |
0086-21-58956006 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList19141/0_EN.htm |
| Company Name: |
Aemon Chemical
|
| Telephone: |
0086-755-86198205 |
| Website: |
www.aemonchem.com |
|