| Identification | Back Directory | [Name]
Methyl 3-pyrrolidinecarboxylate | [CAS]
98548-90-4 | [Synonyms]
Zinc04202762
Zinc04202763
METHYL-PROLINATE
METHYL 3-PYRROLIDINECARBOXYLATE
METHYL PYRROLIDINE-3-CARBOXYLATE
methyl pyrrolidine-3-carboxylate.HCl
NUR NOCH ALS AST63827 !! METHYL-PROLINATE
3-Pyrrolidinecarboxylic acid methyl ester
PYRROLIDINE-3-CARBOXYLIC ACID METHYL ESTER
(72057-18-2) methyl 3-pyrrolidinecarboxylate | [Molecular Formula]
C6H11NO2 | [MDL Number]
MFCD03788461 | [MOL File]
98548-90-4.mol | [Molecular Weight]
129.16 |
| Chemical Properties | Back Directory | [Boiling point ]
92 °C(Press: 17 Torr) | [density ]
1.055±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | [pka]
9.42±0.10(Predicted) |
| Questions And Answer | Back Directory | [Application]
Methyl 3-pyrrolidinecarboxylate can be used as a pharmaceutical synthesis intermediate. It can be prepared from benzyl-trimethylsilylmethylamine as a reactant or from methyl 1-benzyl-2-oxopyrrolidine-4-carboxylic acid as a reactant. |
| Hazard Information | Back Directory | [Synthesis]
Step 1: Benzyl-trimethylsilylmethylamine (100 g, 517 mmol, 1 eq.) was loaded into a 1 L jacketed reactor, followed by 400 mL of THF. The reaction temperature was set to 15 °C and 37% aqueous formaldehyde (53 mL, 647 mmol, 1.25 eq.) was added dropwise o |
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