132-98-9
132-98-9 结构式
基本信息
青霉素 V 钾
青霉素V钾盐
青霉素V钾
PENICILLINE V POTASSIUM SALT
PENICILLIN V
PENICILLIN VK
PENICILLIN V POTASSIUM
PENICILLIN V POTASSIUM SALT
PHENOXYMETHYLPENICILLINIC ACID POTASSIUM SALT
PHENOXYMETHYLPENICILLIN K+ SALT
PHENOXYMETHYLPENICILLIN POTASSIUM
PHENOXYMETHYL PENICILLIN POTASSIUM SALT
4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylicacid,3,3-dimethyl-7-oxo-6-((ph
abicyclo[3.2.0]heptane-2-carboxylate
antibiocin
apsinvk
arcacil
arcasin
aspinvk
beromycin
beromycin(penicillin)
betapen-vk
物理化学性质
安全数据
常见问题列表
Penicillin V (0.002-8.0 mg/L) inhibits the growth of
Streptococci
, with the minimum inhibitory concentrations (MICs) of 0.004-0.008 mg/L.
Penicillin V (0.002-8.0 mg/L) inhibits the growth of
C. difficile
, with a MIC
90
of 8 mg/L.
Penicillin V (0.004-0.063 mg/L; 18 h) inhibits the growth of
Staphylococcus aureus
, with a MIC of 0.016 mg/L.
Penicillin V (0.063-0.25 mg/kg; a single s.c.) inhibits the outgrowth of
S. aureus
in mice thigh muscle.
Penicillin V (100 mg/kg; p.o. once daily for 5 d) avoids the fulminant infection of acute purulent otitis media (AOM) in rats.
Penicillin V (2 mg/kg; a single s.c.) exhibits the plasma half-life (61 min) and mean AUC (0.47 mg/L•h).
| Animal Model: | Specific pathogen free (SPF) male Swiss mice (20-25 g) are inoculated S. aureus |
| Dosage: | 0.063, 0.13, 0.25 mg/kg |
| Administration: | A single s.c. |
| Result: | Decreased the number of CFU (1.34×10 7 counts/mL) compared to controls (3.5×10 7 counts/mL) at the dose of 0.25 mg/kg. |