2628-17-3
中文名称
4-羟基苯乙烯
英文名称
4-Hydroxystyrene
CAS
2628-17-3
EINECS 编号
220-103-6
分子式
C8H8O
MDL 编号
MFCD00017593
分子量
120.15
MOL 文件
2628-17-3.mol
更新日期
2024/04/18 16:41:14
2628-17-3 结构式
基本信息
中文别名
4-乙烯苯酚4-羟基苯乙烯
4-乙烯基苯酚
4-乙烯基苯酚, 大约为10%丙二醇溶液
英文别名
4-HYDROXYSTYRENE4-VINYLPHENOL
FEMA 3739
4-ethenylphenol
Phenol, 4-ethenyl-
p-hydroxystyrene
p-vinyl-pheno
p-vinylphenol
p-vinyl-phenol
4-hydroxystyrene (4-vinylphenol)
4-Vinylphenol in 10% sol. Propylene glycol
4-Vinylphenol solution 10 wt. % in propylene glycol
4-Vinylphenol,10%soln.inpropyleneglycol
4-vinylphenol,4-ethenyl-phenol,p-hydroxystyrene
PARA-VINYLPHENOL
4-VINYLPHENOL, CA 10% SOLN. IN PROPYLENE GLYCOL
4-VINYLPHENOL (10% SOLUTION IN PROPYLENE GLYCOL)
4-VINYL PHENOL 10% IN PROPYLENE GLYCOL
p-Oxystyrene
Styrene-4-ol
所属类别
食品添加剂: 食用香料（增香剂）: 天然等同香料和人造香物理化学性质
熔点73 °C
沸点228.85°C (estimate)
密度1.04
蒸气压9.38hPa at 25℃
FEMA3739
折射率1.4440
闪点>230 °F
储存条件Inert atmosphere,2-8°C
溶解度可溶于氯仿（少量）、DMSO（少量）
酸度系数(pKa)9.95±0.26(Predicted)
形态液体
颜色透明无色至橙色
气味 (Odor)at 0.01 % in propylene glycol. chemical phenolic medicinal sweet
香型酚类
水溶解性Slightly miscible with water.
敏感性吸湿性
JECFA Number711
BRN506844
稳定性感光
LogP2.3 at 25℃
NIST化学物质信息4-hydroxystyrene(2628-17-3)
EPA化学物质信息Phenol, 4-ethenyl- (2628-17-3)
常见问题列表
毒性
GRAS(FEMA)。使用限量
FEMA(mg/kg)：焙烤制品、肉制品、调味汁，5.0；冷饮、甜沙司，2.5；凝胶、布丁、甜点、糖霜、果仁制品、硬糖，2.0；无醇饮料1.5；含醇饮料0.5；代乳品3.0；胶姆糖10.0。生物活性
4-Vinylphenol 存在于药用草白花蛇舌草，野生稻中，也是葡萄酒中乳酸菌对对香豆酸和阿魏酸的代谢产物。4-Vinylphenol 诱导凋亡 (apoptosis)，在体内抑制血管形成并抑制浸润性乳腺肿瘤生长。体外研究
4-Vinylphenol (12.5-200 µg/mL) significantly reduces cell viability in parental MDA-MB-231 cells, and the IC50 value is 109 µg/mL.
4-Vinylphenol (0.15 or 0.3 µg/mL; 3 days) reduces sphere‑formation and vimentin expression on CSCs in breast cancer.
4-Vinylphenol (50, 100 µg/mL; 72 hours) significantly suppresses cell proliferation in CSC-enriched MDA-MB-231 cells. 4-Vinylphenol significantly reduces ALDH1A1 expression by 50% in CSC-enriched MDA-MB-231 cells.
4-Vinylphenol (100 µg/mL) significantly increases the expressions of caspase 3, likely sensitizing CSC-enriched MDAMB-231 cells to apoptosis.
对羟基苯乙烯价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/01/25 | HY-W005288 | 4-羟基苯乙烯 4-Vinylphenol | 2628-17-3 | 100mg(832.2mM * 1mL in Propylene glycol) | 500元 |
| 2024/01/16 | L10902 | 4-乙烯基苯酚, min 10% 丙二醇溶液 4-Vinylphenol, min 10% soln. in propylene glycol | 2628-17-3 | 1g | 563元 |
| 2024/01/16 | L10902 | 4-乙烯基苯酚, min 10% 丙二醇溶液 4-Vinylphenol, min 10% soln. in propylene glycol | 2628-17-3 | 5g | 1935元 |