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348-67-4

中文名称 D-蛋氨酸
英文名称 D-Methionine
CAS 348-67-4
EINECS 编号 206-483-6
分子式 C5H11NO2S
MDL 编号 MFCD00002622
分子量 149.21
MOL 文件 348-67-4.mol
更新日期 2024/04/19 09:18:31
348-67-4 结构式 348-67-4 结构式

基本信息

中文别名
D-2-氨基-4-甲硫基丁酸
D-蛋氨酸
D-甲硫氨酸
D-蛋氨酸/D-甲硫氨酸
英文别名
D-2-AMINO-4-[METHYLTHIO]BUTANOIC ACID
d-2-amino-4-(methylthio)butyric acid
D-BANTHIONINE
D-LOBAMINE
D-METHIONINE
H-D-MET-OH
(R)-2-AMINO-4-(METHYLMERCAPTO)BUTYRIC ACID
(r)-methionine
d-methionin
D-Metionien
Methionine d-form
Methionine, D-
R-Methionine
D-METHIONINE, 99+% (98% EE/GLC)
D-Methionine,99%
(r)-2-amino-4-(methylthio)butyric acid
D-Methionine (9CI)
Methionine, D- (8CI)
NSC 45689
d-metionien (australian)
所属类别
生物化工:常见氨基酸及蛋白质类

物理化学性质

外观性状D-蛋氨酸为白色结晶。溶于水、稀酸及碱,极微溶于醇,不溶于醚。
熔点273-275 °C
比旋光度-24 º (c=8, 6N HCl)
沸点306.9±37.0 °C(Predicted)
密度1.113 (estimate)
折射率1.5216 (estimate)
储存条件0-6°C
溶解度53g/l(20°C)
酸度系数(pKa)2.23±0.10(Predicted)
形态粉末
颜色白色至灰白色
水溶解性53 g/L (20 ºC)
Merck14,5975
BRN1722293
稳定性稳定的。与强氧化剂不相容。
LogP0.370 (est)
NIST化学物质信息D-(l)-Methionine(348-67-4)
EPA化学物质信息D-Methionine (348-67-4)

安全数据

危险性符号(GHS)
GHS07
警示词警告
危险品标志Xi
危险类别码R33
安全说明S22-S24/25
WGK Germany3
RTECS号PD0455000
TSCAYes
海关编码29309090

应用领域

用途一
用作生化试剂。

化学品安全说明书(MSDS)

D-蛋氨酸价格(试剂级)
报价日期产品编号产品名称CAS号包装价格
2024/01/16B21213D-蛋氨酸, 99%
D-Methionine, 99%
348-67-45g222元
2024/01/16B21213D-蛋氨酸, 99%
D-Methionine, 99%
348-67-425g908元
2024/01/16B21213D-蛋氨酸, 99%
D-Methionine, 99%
348-67-4100g3631元

常见问题列表

生物活性
Methionine (MRX-1024; D-Methionine) 是一种有效的化学保护剂,它还可以通过激活 GABAA 受体来抑制神经元活性。
靶点

GABA A receptor

体外研究

The incubation of human plasma with Methionine (D-methionine) and CP leads to the formation of a Pt-D-methionine complex independent of the order of addition. In plasma, an early CP hydrolysis product reacts with Methionine to form a 1:1 complex that is followed by the formation of a 2:1 compound at a later time point. The formation of these Pt-D-methionine species plays an important role in the processes by which Methionine protects mammalian organisms against CP-induced toxicities.

体内研究

When Methionine (D-methionine) is administered along with cisplatin the cell density is 0.8±0.070 (SEM), significantly larger than in rats treated with only cisplatin (P<0.01) while not significantly different from controls or from animals treated only with D-methionine (P>0.05). When Methionine is administered alone the average cell density is 0.95±0.099 (SEM) and not significantly different from controls (P>0.05).

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