3485-62-9
中文名称
克利溴铵
英文名称
Clidinium bromide
CAS
3485-62-9
EINECS 编号
222-471-3
分子式
C22H26BrNO3
MDL 编号
MFCD00078996
分子量
432.35
MOL 文件
3485-62-9.mol
更新日期
2023/03/20 15:41:19
3485-62-9 结构式
基本信息
中文别名
可立啶克利溴铵
溴奎环二苯酯
(1-甲基-1-氮杂双环[2.2.2]辛-8-基) 2-羟基-2,2-二苯基乙酸酯溴化物
英文别名
3-HYDROXY-1-METHYLQUINUCLIDINIUM BROMIDE BENZILATE3-[(HYDROXYPHENYLACETYL)OXY]-1-METHYL-1-AZONIABICYCLO[2,2,2]OCTANE BROMIDE
CLIDINIUM BROMIDE
QUARZAN
RO-2-3773
1-methyl-3-benzil-oxyloxy-quinuclidiniumbromide
3-((hydroxydiphenylacetyl)oxy)-1-methyl-1-azoniabicyclo(2.2.2)octanbromi
3-(2,2-diphenyl-2-hydroxyethanoyloxy)-quinuclidiniumbromide
3-(benziloyloxy)-1-methylquinuclidiniumbromide
benzilicacid,esterwith3-hydroxy-1-methylquinuclidinium
quarzanbromide
quinuclidinium,3-hydroxy-1-methyl-,bromide,benzilate
quinuclidinolmethylbromide,benzilate
3-[(Hydroxyphenylacetyl)oxy]-1-methyl-1-azoniabicyclo[2,2,2]octane Bromide, Ro-2-3773, Quarzan
Clidinium
(1-Methyl-1-azoniabicyclo[2.2.2]octan-8-yl) 2-hydroxy-2,2-diphenylacetate bromide
1-Azoniabicyclo[2.2.2]octane, 3-[(hydroxydiphenylacetyl)oxy]-1-methyl-, bromide
3-[(Hydroxydiphenylacetyl)oxy]-1-methyl-1-azoniabicyclo[2.2.2]octane bromide
Ro-3773
3-[(Hydroxydiphenylacetyl)oxy]-1-methyl-1-azoniabicyclo[2.2.2]octane
所属类别
生物化工：激动剂抑制剂物理化学性质
熔点240-241°C
储存条件Inert atmosphere,Room Temperature
溶解度可溶于DMSO（轻微）、甲醇（轻微、超声处理）、水（轻微）
形态neat
颜色白色至灰白色
克利溴铵价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/04/30 | HY-B1132 | 克利溴铵 Clidinium bromide | 3485-62-9 | 100mg | 500元 |
| 2024/04/30 | HY-B1132 | 克利溴铵 Clidinium bromide | 3485-62-9 | 10mM * 1mLin DMSO | 550元 |
| 2024/04/30 | S5480 | 克利溴铵 Clidinium Bromide | 3485-62-9 | 25mg | 877.33元 |
常见问题列表
生物活性
Clidinium bromide 是一种季胺抗毒蕈碱 (antimuscarinic) 剂。Clidinium bromide 可以通过减少胃酸和减慢肠道速度来缓解痉挛和腹部/胃疼的症状。体内研究
Clidinium (oral gavage; 0.25, 0.5, and 1 mg/kg; 3 days) causes constipation in mice. It leads to a significant decrease in %transit after clidinium treatment [(F(3, 28)=27.405] in mice.Clidinium (oral gavage; 0.25, 0.5, and 1 mg/kg; 3 days) has a significant effect on the clonic seizure threshold induced by intravenous PTZ which received clidinium (0.25, 0.5, and 1 mg/kg) [(F(3, 35) = 14.103].
| Animal Model: | Male NMRI mice weighing 20-25 g |
| Dosage: | 0.25, 0.5, and 1 mg/kg |
| Administration: | Oral gavage; 0.25, 0.5, and 1 mg/kg; 3 days |
| Result: | Decreased the clonic seizure latency compared with control animals. |