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Somatotropin (human) Produkt Beschreibung

GROWTH HORMONE, HUMAN Struktur
12629-01-5
CAS-Nr.
12629-01-5
Bezeichnung:
Somatotropin (human)
Englisch Name:
GROWTH HORMONE, HUMAN
Synonyma:
GH;STH;HGH;cb311;D02691;sj0011;Nutropin;ly137998;crecormon;LY-137988
CBNumber:
CB1151396
Summenformel:
C990H1529N263O299S7
Molgewicht:
22124.12
MOL-Datei:
Mol file

Somatotropin (human) Eigenschaften

alpha 
25 -38.7° (0.1M acetic acid)
storage temp. 
2-8°C
Aggregatzustand
lyophilized powder

Sicherheit

Kennzeichnung gefährlicher B
WGK Germany  3
RTECS-Nr. TO7385000
HS Code  2937110000

Somatotropin (human) Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Somatotropin, a second-generation (methionine-free) human growth hormone produced by recombinant technology, was launched in the U.S.A. for the treatment of growth failure in children due to chronic renal insufficiency before transplantation and for the long term treatment of short stature in children with growth failure due to a lack of endogenous growth hormone secretion. The efficacy of somatotropin is reportedly comparable to the first biosynthetic growth hormone somatrem, which contains a methionyl residue, but with less frequent antibody formation and rarely causes allergic effects or impairs growth response. Somatotropin is also in clinical trials for the treatment of growth hormone deficiency in adults and is currently under approval review for Turner's syndrome.

Beschreibung

Somatropin is a growth hormone useful in the treatment of hypopituitaxy dwarfism and other disorders resulting from growth hormone deficiencies. Lilly has used recombinant technology to produce human somatropin identical to the natural hormone. Somamm, the N-methionyl derivative of somatropin, was launched in 1985 by Genentech for the same indications.

Chemische Eigenschaften

White or almost white powder.

Originator

Genentech (U.S.A.)

Originator

Lilly (USA)

Verwenden

Human Growth Hormone is a hormone (growth).

Trademarks

(Genentech); Genotropin (Pharmacia); Humatrope (Lilly);Nutropin (Genentech); Saizen (Serono); Serostim (Serono);22krl;Antuitrin growth;Antuitrin-t;Asellacrin;Cb 311;Corpormon;Crescormon;Grorm;Human groth hormone;Human growth hormon;Leutrophin;Nanormin;Nanormon;Phynatol;Phyol;Phyoneon;Protopin;Protropin;Rx 099916;Somacton;Somatonorm;Somatormone;Somatotrope choay;Somatrofin;Somatropin;Nutropln.

Weltgesundheitsorganisation (WHO)

Somatropin, a pituitary-derived human growth hormone, has been used in the treatment of hypopituitary dwarfism for over twenty years. In 1985 it became known that Creutzfeldt-Jakob disease, a potentially fatal form of brain degeneration resulting from a slow neurotropic viral infection, had developed in several patients who had received preparations of somatropin in the late 1960s/early 1970s. This led to the withdrawal of these preparations in many countries. An international collaborative effort was maintained to identify newlydiagnosed cases. By 1990 a total of 30 such cases had been notified. More efficient purification procedures introduced during the 1970s greatly reduced the risk of viral contamination, but products containing pituitary-derived somatropin have been superseded by biosynthetically-manufactured preparations produced using recombinant techniques.

Allgemeine Beschreibung

Somatropin for injection(Humatrope) is a natural-sequence human GH of rDNAorigin. Its composition and sequence of amino acids areidentical with those of human GH of pituitary origin. It isadministered intramuscularly or subcutaneously. Thedosage range is 0.05 to 0.1 IU.

Clinical Use

Human Growth Hormone(hGH) is a protein that is essential for normal growth and developmentin humans. Human Growth Hormone(hGH) affects many aspects of humandevelopment and metabolism including longitudinalgrowth, regulation (increase) of protein synthesis and lipolysis,and regulation (decrease) of glucose metabolism. Human Growth Hormone(hGH)has been used as a drug since the 1950s, and it has been extremelysuccessful in the treatment of classic growth hormonedeficiency, chronic renal insufficiency, Turner syndrome,failure to lactate in women, and Prader-Willisyndrome. In its long history, the hormone has been remarkablysuccessful and free of side effects.

Somatotropin (human) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Somatotropin (human) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 78)Lieferanten
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
Rixing Chemical CO.,LTD
13237129059
- info@rixingchemi.com CHINA 235 55
Hebei Minshang Biotechnology Co., Ltd
+86-13582176207
cathy@hbminshang.com CHINA 272 58
Hebei Huanhao Biotechnology Co., Ltd.
86-0311-83975816 whatsapp +8618034554576
86-0311-83975816 grace@hbhuanhao.com CHINA 698 58
Hebei Guanlang Biotechnology Co., Ltd.
+8619930501651
breeduan@crovellbio.com CHINA 2314 58
Hebei Chisure Biotechnology Co., Ltd.
+8613292890173
0311 66567340 luna@speedgainpharma.com CHINA 1017 58
hdzhl biotechnology co., ltd
86-13032617415
sales@luchibiology.com CHINA 1173 58
Hebei shuoxi biotechnology co. LTD
+8613081092107
julia@hbshuoxi.com CHINA 38 58
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21726 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20672 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30002 58

12629-01-5(Somatotropin (human))Verwandte Suche:


  • GROWTH HORMONE, HUMAN CAS 12629-01-5 HGH kf-wang(at)kf-chem.com
  • cb311
  • crecormon
  • SOMATOTROPIN (STH), HUMAN PITUITARY, RECOMBINANT, EXPRESSED IN ESCHERICHIA COLI
  • RecombinantHumanGrowthHormonePowderMateirals/Rhgh
  • SomatropinForInjection/RhghForInjection
  • RecombinantHumanGrowthHormoneForInjection/Rhgh
  • SomatropinPowderMaterials/Rhgh
  • somatotropin (sth) from human pituitary
  • Genotropin
  • GROWTH HORMONE, FROM HUMAN PITUITARY, IODINATION GRADE
  • LY-137988
  • Asellacrin
  • Asellacrin (tn)
  • D02691
  • Nutropin
  • Nutropin (tn)
  • Omnitrope
  • Omnitrope (tn)
  • Somatropin (genetical recombination)
  • Somatropin (8.63 USP Somatropin Units/vial) (INTERNATIONAL COLD CHAIN SHIPMENT REQUIRED)
  • SoMatotropin (huMan)(9CI)
  • Growth hormone 1
  • Growth Hormone from chicken
  • Recombinant human somatotropin
  • human growth hormone lila@tuskwei.com
  • HGH high quality Cas no.:12629-01-5
  • HGH somatropin CAS12629-01-5 Human Growth Hormone
  • HGH Growth hormone somatotropin human growth hormone
  • Growth Hormone, Human, recombinant [Somatropin]
  • humatrope
  • ly137998
  • norditropin
  • sj0011
  • OVINE SOMATOTROPIN
  • SOMATOTROPIN
  • SOMATOTROPIN, HUMAN
  • SOMATROPIN
  • STH
  • BOVINE GH
  • BOVINE GROWTH HORMONE
  • BOVINE SOMATOTROPIN
  • GROWTH HORMONE
  • GROWTH HORMONE, HUMAN
  • GROWTH HORMONE, HUMAN PITUITARY
  • GH
  • GH, HUMAN
  • HGH
  • HGH HUMAN
  • HUMAN GROWTH HORMONE
  • Somatropin, Rghg
  • HGH somatropin Human Growth Hormone
  • 12629-01-5
  • C990H1529N263O299S7
  • Hormones
  • Pituitary Hormones
  • Cytokines, Growth Factors and Hormones
  • Cell Biology
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