NSC 150117 hydrochloride

95130-23-7

CAS-Nr.: 95130-23-7

Englisch Name:: NSC 150117 hydrochloride

Synonyma:: (E/Z)-BCI;BCI (hydrochloride);(E)-BCI hydrochloride;(E/Z)-BCI hydrochloride;NSC 150117 hydrochloride;BCI hydrochloride - NSC 150117 hydrochloride;(2Z)-2-benzylidene-3-(cyclohexylamino)-3H-inden-1-one;2-benzylidene-3-(cyclohexylamino)-1-Indanone hydrochloride;(E)-2-benzylidene-3-(cyclohexylamino)-2,3-dihydro-1H-inden-1-one;3-(cyclohexylamino)-2,3-dihydro-2-(phenylmethylene)-1Hinden-1-one

CBNumber:: CB12756032

Summenformel:: C22H24ClNO

Molgewicht:: 353.885

MOL-Datei:: 95130-23-7.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 16

NSC 150117 hydrochloride Eigenschaften

storage temp.: 2-8°C

Löslichkeit: DMSO: soluble10mg/mL, clear

Aggregatzustand: powder

Farbe: white to beige

Sicherheit

WGK Germany	3

NSC 150117 hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

(E/Z)-BCI hydrochloride has been used:

to evaluate the role of the Duox-H₂O₂-Dusp6 derepression signaling pathway in heart regeneration
as an MKP-1 inhibitor to investigate the role of MKP-1 on bexarotent-induced effects
as a dual specificity phosphatase 6 (DUSP6) inhibitor to study its effects on the proliferation of SKOV3 cells

Biochem/physiol Actions

BCI is an allosteric inhibitor of Dusp6 that acts within the phosphatase domain to prevent the catalytic stimulation of phosphatase activity induced by ERK2 substrate binding. BCI also hyperactivates FGF signaling, since Dusp6 functions as a feedback regulator of FGF signaling.

NSC 150117 hydrochloride Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

NSC 150117 hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 16)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58
Shanghai Han-Xiang Chemical Co., Ltd.	15971444841	amber@biochempartner.com	China	3063	58
Changzhou Chenhong Biotechnology Co., Ltd.	0519-85788828 13775037613	sales@chemrenpharm.com	China	3538	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
Shanghai hongqu biomedical technology co. LTD	88888888888	hongquchem@qq.com	China	5132	58
Beijing Jin Ming Biotechnology Co., Ltd.	010-60605840 15801484223	psaitong@jm-bio.com	China	29834	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24131	58

(E)-2-benzylidene-3-(cyclohexylamino)-2,3-dihydro-1H-inden-1-one
(E/Z)-BCI hydrochloride
2-benzylidene-3-(cyclohexylamino)-1-Indanone hydrochloride
3-(cyclohexylamino)-2,3-dihydro-2-(phenylmethylene)-1Hinden-1-one
NSC 150117 hydrochloride
BCI (hydrochloride)
(E/Z)-BCI
BCI hydrochloride - NSC 150117 hydrochloride
(2Z)-2-benzylidene-3-(cyclohexylamino)-3H-inden-1-one
(E)-BCI hydrochloride
95130-23-7