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Zwischenprodukte der aktiven pharmazeutischen Wirkstoffen (APIs) >(aR,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-trimethyl-alpha-(2-methylpropyl)-4,6-methano-1,3,2-benzodioxaborole-2-methanamine 2,2,2-trifluoroacetate
(aR,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-trimethyl-alpha-(2-methylpropyl)-4,6-methano-1,3,2-benzodioxaborole-2-methanamine 2,2,2-trifluoroacetate
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- CAS-Nr.
- 179324-87-9
- Englisch Name:
- (aR,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-trimethyl-alpha-(2-methylpropyl)-4,6-methano-1,3,2-benzodioxaborole-2-methanamine 2,2,2-trifluoroacetate
- Synonyma:
- (1R)-(S)-PINANEDIOL 1-AMMONIUM TRIFLUOROACETATE-3-METHYLBUTANE-1-BORONATE;(R)-3-Methyl-1-((3aS,4S,6S,7aR)-3a,5,5-triMethylhexahydro-4,6-Methanobenzo[d][1,3,2]dioxaborol-2-yl)butan-1-aMine 2,2,2-trifluoroacetate;2,6<SUP>/SUP>(R)-BoroL;6-methano-1;Bortezomib INT A;eu-(+)-PinanedioL;7aR)-Hexahydro-3a
- CBNumber:
- CB21511721
- Summenformel:
- C17H29BF3NO4
- Molgewicht:
- 379.23
- MOL-Datei:
- 179324-87-9.mol
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(aR,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-trimethyl-alpha-(2-methylpropyl)-4,6-methano-1,3,2-benzodioxaborole-2-methanamine 2,2,2-trifluoroacetate Eigenschaften
- Schmelzpunkt:
- 157-159°C
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- Löslichkeit
- Ethanol (Slightly), Methanol (Slightly)
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- InChI
- InChI=1/C15H28BNO2.C2HF3O2/c1-9(2)6-13(17)16-18-12-8-10-7-11(14(10,3)4)15(12,5)19-16;3-2(4,5)1(6)7/h9-13H,6-8,17H2,1-5H3;(H,6,7)/t10-,11-,12+,13-,15-;/s3
- InChIKey
- SRFQKJZNJYTMNI-XXOUUVOINA-N
- SMILES
- C(F)(F)(F)C(=O)O.C[C@@]12OB([C@@H](N)CC(C)C)O[C@]1([H])C[C@]1([H])C[C@@]2([H])C1(C)C |&1:8,11,18,21,24,r|
- CAS Datenbank
- 179324-87-9(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
|
| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H332 |
Gesundheitsschädlich bei Einatmen. |
Akute Toxizität inhalativ |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P261, P271, P304+P340, P312 |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizität (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
|
|
| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen. |
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(aR,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-trimethyl-alpha-(2-methylpropyl)-4,6-methano-1,3,2-benzodioxaborole-2-methanamine 2,2,2-trifluoroacetate Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
White Solid
Verwenden
Bortezomib (B675700) intermediate. A boronic acid dipeptide derivative as proteasome inhibitors.
(aR,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-trimethyl-alpha-(2-methylpropyl)-4,6-methano-1,3,2-benzodioxaborole-2-methanamine 2,2,2-trifluoroacetate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
(aR,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-trimethyl-alpha-(2-methylpropyl)-4,6-methano-1,3,2-benzodioxaborole-2-methanamine 2,2,2-trifluoroacetate Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 336)Lieferanten
| Firmenname |
Telefon |
E-Mail |
Land |
Produktkatalog |
Edge Rate |
|
Zhengzhou Anbu Chem Co.,Ltd
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+86-0371-88006763; +8615988602810
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sales@anbuchem.com |
China |
3000 |
58 |
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SHANDONG BOYUAN PHARMACEUTICAL CO., LTD.
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+86-0531-69954981 +8615666777973
|
dwyane.wang@boyuanpharm.com |
China |
211 |
58 |
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Sinoway Industrial co., ltd.
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0592-5800732; +8613806035118
|
xie@china-sinoway.com |
China |
992 |
58 |
|
Henan Fengda Chemical Co., Ltd
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+86-371-86557731 +86-13613820652
|
info@fdachem.com |
China |
7845 |
58 |
|
Shaanxi TNJONE Pharmaceutical Co., Ltd
|
+8618740459177
|
sarah@tnjone.com |
China |
893 |
58 |
|
Capot Chemical Co.,Ltd.
|
571-85586718 +8613336195806
|
sales@capotchem.com |
China |
29797 |
60 |
|
Shanghai Daken Advanced Materials Co.,Ltd
|
+86-371-66670886
|
info@dakenam.com |
China |
15928 |
58 |
|
Beijing Cooperate Pharmaceutical Co.,Ltd
|
010-60279497
|
sales01@cooperate-pharm.com |
CHINA |
1811 |
55 |
|
Henan Tianfu Chemical Co.,Ltd.
|
+86-0371-55170693 +86-19937530512
|
info@tianfuchem.com |
China |
21691 |
55 |
|
Shanghai Time Chemicals CO., Ltd.
|
+86-021-57951555 +8617317452075
|
jack.li@time-chemicals.com |
China |
1807 |
55 |
179324-87-9()Verwandte Suche:
- (R)-BoroLeu-(+)-Pinanediol-CF3COOH
- (R)-BoroLeu-(+)-Pinanediol-CF3CO2H
- (aR,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-trimethyl-alpha-(2-methylpropyl)-4,6-methano-1,3,2-benzodioxaborole-2-methanamine 2,2,2-trifluoroacetate
- (αR)-(1S,2S,3R,5S)-Pinanediol-1-amino-3-methylbutane-1-boronate Trifluoroacetate
- Bortezomib Intermediate 1
- (R)-BoroLeu-(+)-Pinanediol trifluoroacetate
- (αR,3aS,4S,6S,7aR)-
- (alphaR,3as,4s,6s,7ar)-Hexahydro-3a,8,8-triMethyl-alpha-(2-Methylpropyl)-4,6-Methano-1,3,2-benzodioxaborole-2-MethanaMine 2,2,2-trifluoroacetate
- Pinanedioltrifluoroacetate salt-
- BortezoMib I(aR,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-triMethyl-alpha-(2-Methylpropyl)-4,6-Methano-1,3,2-benzodioxaborole-2-MethanaMine 2,2,2-trifluoroacetate
- (R)-3-Methyl-1-((3aS,4S,6S,7aR)-3a,5,5-triMethylhexahydro-4,6-Methanobenzo[d][1,3,2]dioxaborol-2-yl)butan-1-aMiniuM 2,2,2-trifluoroacetate
- (αR)-(1S,2S,3R,5S)-Pinanediol-1-aMino-3-Methylbutane-1-boronate Trifluoroacetic Acid Salt
- (R)-Boroleucine-(1S,2S,3R,5S)-(+)-pinanediol ester trifluoroacetate
- Bortezomib Intermediates
- Ixazomib intermediate
- (aR,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-trimethyl-alpha-(2-methylpropyl)-4,6-methano-1,3,2-benzodioxaborole-2-methamine 2,2,2-trifluoroacetate
- Bortezomib INT A
- (R)-BoroLeu-(+)-Pinanediol-CF3COOH N-4
- (1R)-(S)-pinanediol 1-aMMoniuM trifiuoroacetate-3-Methylbutane-1-boronate
- (R)-Boroleucine-(1S,2S,3R,5S)-(+)-pinanediol ester trifluoroacetate 98%
- (aR,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-trimethyl-α-(2-methylpropyl)-4,6-methano-1,3,2-benzodioxaborole-2-methanamine 2,2,2-trifluoroacetate
- (R)-3-Methyl-1-[(3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methano-1,3,2-benzodioxaborol-2-yl]-1-butanamine 2,2,2-Trifluoroacetate
- BoroLeu-(+)-Pinanediol
- (1R)-3-methyl-1-[(1S,2S,6R,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.0<
- /SUP>
- ]decan-4-yl]butan-1-amine
- 2,6<
- SUP>
- (aR,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-trimethyl-α-(2-methylpropyl)-4,6-methano-1,3,2-benzodioxaborole-
- (R)-BoroL
- eu-(+)-PinanedioL
- (1S,2S,3R,5S)-Pinane-2,3-diol leucineboronate trifluoroacetate salt
- (aR,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-trimethyl-alpha-(2-methylpropyl)-4,6-methano-1,3,2-benzodioxabor
- Bortezomib Intermediate A
- 4,6-Methano-1,3,2-benzodioxaborole-2-methanamine, hexahydro-3a,8,8-trimethyl-α-(2-methylpropyl)-, (αR,3aS,4S,6S,7aR)-, 2,2,2-trifluoroacetate (1:1)
- Ixazomib Impurity 28
- 2-benzodioxaborole-2-methanamine 2
- 6-methano-1
- 7aR)-Hexahydro-3a
- 8-trimethyl-alpha-(2-methylpropyl)-4
- (R)-BoroLeu-(+)-Pinanediol trifluoroacetate (Bortezomib Impurity)
- Bortezomib Amino R Isomer
- (aR,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-trimethyl-alpha-(2-methy...
- (1R)-(S)-Pinanediol 1-ammonium trifluoroacetate-3-methylbutane-1-boronate (TFA)
- (αR)-(1S,2S,3R,5S)-Pinanediol-1-amino-3-methylbutane-1-boronate Trifluoroacetate
- (1R)-(S)-pinanediol-1-Ammonium Trifluoroacetate-3-methlbutane-1-boronate
- (αR)-(1S,2S,3R,5S)-Pinanediol-1-amino-3-methylbutane-1-boronate Trifluoroacetic Acid Salt
- (1R)-(S)-PINANEDIOL 1-AMMONIUM TRIFLUOROACETATE-3-METHYLBUTANE-1-BORONATE
- (R)-3-Methyl-1-((3aS,4S,6S,7aR)-3a,5,5-triMethylhexahydro-4,6-Methanobenzo[d][1,3,2]dioxaborol-2-yl)butan-1-aMine 2,2,2-trifluoroacetate
- (R) Pinanediol 1-amino-3-methylbutyl borate trifluoroacetate
- 4,6-Methano-1,3,2-benzodioxaborole-2-methanamine, hexahydro-3a,8,8-trimethyl-α-(2-methylpropyl)-, (αR,3aS,4S,6S,7aR)-,2,2,2-trifluoroacetate (1:1)
- (aR,3aS,4S,6S,7aR)- hexahydro -3a,8,8- trimethyl -alpha-(2- methylpropyl) -4,6- methyl bridge -1,3,2- benzodioxolane -2- methylamine 2,2,2- trifluoroacetate
- (αR,3aS,4S,6S,7aR)-hexahydro-3a,8,8-trimethyl-α-(2-methylpropyl)-4,6-Methano-1,3,2-benzodioxaborole-2-methanamine 2,2,2-trifluoroacetate (1:1)
- (aR,3aS,4S,6S,7aR)-Hexahydro-3a,5,5-trimethyl-a-(2-methylpropyl)-4,6-methano-1,3,2-benzodioxaborole-2-methanamine TFA
- (R)-Boroleucine (1S 2S 3R 5S)-(+)-2 3-pinanediol ester trifluoroacetate.
- (R)-1-Amino-3-methylbutylboronic acid pinanediol ester trifluoroacetate
- (R)-BoroLeu-(+)-Pinanedioltrifluoroacetate salt
- (aR,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-trimethyl-alpha-(2-methylpropyl)-4,6-methano-1,3,2-benzodiox
