(1-Methylethyl)benzol Chemische Eigenschaften,Einsatz,Produktion Methoden
ERSCHEINUNGSBILD
FARBLOSE FLüSSIGKEIT MIT CHARAKTERISTISCHEM GERUCH.
PHYSIKALISCHE GEFAHREN
Fließen, Schütten o.ä. kann zu elektrostatischer Aufladung führen.
CHEMISCHE GEFAHREN
Reagiert sehr heftig mit Säuren und starken Oxidationsmitteln unter Feuer- und Explosionsgefahr. Bildung explosionsfähiger Peroxide.
ARBEITSPLATZGRENZWERTE
TLV: 50 ppm (als TWA); (ACGIH 2005).
MAK: 20 ppm 250 mg/m? Spitzenbegrenzung: überschreitungsfaktor II(4); Hautresorption; Schwangerschaft: Gruppe C; (DFG 2005).
AUFNAHMEWEGE
Aufnahme in den Körper durch Inhalation und über die Haut.
INHALATIONSGEFAHREN
Beim Verdampfen bei 20°C tritt langsam eine gesundheitsschädliche Kontamination der Luft ein.
WIRKUNGEN BEI KURZZEITEXPOSITION
WIRKUNGEN BEI KURZZEITEXPOSITION: Die Flüssigkeit reizt die Augen und die Haut. Verschlucken kann zur Aufnahme in der Lunge führen; Gefahr der Aspirationspneumonie. Möglich sind Auswirkungen auf das Zentralnervensystem. Exposition weit oberhalb der Arbeitsplatzgrenzwerte kann zu Bewusstlosigkeit führen.
WIRKUNGEN NACH WIEDERHOLTER ODER LANGZEITEXPOSITION
Wiederholter oder andauernder Hautkontakt kann Dermatitis hervorrufen.
LECKAGE
Ausgelaufene Flüssigkeit möglichst in abdichtbaren Behältern sammeln. Reste mit Sand oder inertem Absorptionsmittel aufnehmen und an einen sicheren Ort bringen. NICHT in die Umwelt gelangen lassen. Persönliche Schutzausrüstung: Atemschutzfilter für organische Gase und Dämpfe.
R-Sätze Betriebsanweisung:
R10:Entzündlich.
R37:Reizt die Atmungsorgane.
R51/53:Giftig für Wasserorganismen, kann in Gewässern längerfristig schädliche Wirkungen haben.
R65:Gesundheitsschädlich: kann beim Verschlucken Lungenschäden verursachen.
S-Sätze Betriebsanweisung:
S24:Berührung mit der Haut vermeiden.
S37:Geeignete Schutzhandschuhe tragen.
S61:Freisetzung in die Umwelt vermeiden. Besondere Anweisungen einholen/Sicherheitsdatenblatt zu Rate ziehen.
S62:Bei Verschlucken kein Erbrechen herbeiführen. Sofort ärztlichen Rat einholen und Verpackung oder dieses Etikett vorzeigen.
Aussehen Eigenschaften
C9H12; Isopropylbenzol, 2-Phenylpropan. Farblose Flüssigkeit mit aromatischem Geruch.
Gefahren für Mensch und Umwelt
Reizt die Atmungsorgane, Augen und die Haut. Wird auch über die Haut aufgenommen. Kann zu Schläfrigkeit, Erregung und Krämpfen bis zur Narkose führen.
Bildung von Peroxiden möglich. Entzündlich.
LD
50 (oral, Ratte) 1400 mg/kg.
Schutzmaßnahmen und Verhaltensregeln
Schutzhandschuhe als kurzzeitiger Spritzschutz.
Verhalten im Gefahrfall
Mit flüssigkeitsbindendem Material, z.B. Rench Rapid aufnehmen. Der Entsorgung zuführen. Nachreinigen.
Kohlendioxid, Pulver, Schaum.
Brennbar. Dämpfe schwerer als Luft. Mit Luft Bildung explosionsfähiger Gemische.
Erste Hilfe
Nach Hautkontakt: Mit reichlich Wasser abwaschen.
Nach Augenkontakt: Mit reichlich Wasser bei geöffnetem Lidspalt mindestens 15 Minuten ausspülen. Sofort Augenarzt hinzuziehen.
Nach Einatmen: Frischluft. Arzt hinzuziehen.
Nach Verschlucken: Reichlich Wasser trinken lassen. Erbrechen auslösen. Arzt hinzuziehen.
Nach Kleidungskontakt: Kontaminierte Kleidung entfernen.
Ersthelfer: siehe gesonderten Anschlag
Sachgerechte Entsorgung
Als halogenfreie, organische Lösemittelabfälle.
Beschreibung
Cumene is a common name for isopropylbenzene, an organic
compound. Cumene is a volatile colorless liquid at room
temperature with a characteristic sharp, penetrating, aromatic
odor. It is insoluble in water but is soluble in alcohol and many
other organic solvents. Cumene is structurally a member of the
alkyl aromatic family of hydrocarbons, which also includes
toluene (methylbenzene) and ethylbenzene.Cumene can be
found in crude oil, refined fuels, and is a part of processed highoctane
gasoline.
Cumene is manufactured by reacting benzene with
propylene at elevated temperature and pressure in the presence
of a catalyst. It is considered an environmental pollutant
because it is a natural component of petroleum and is present
in tobacco smoke. Cumene vapor can be absorbed by the respiratory tract. Sufficiently high levels of exposure to cumene
causes central nervous system (CNS) depression leading to
death, internal bleeding of numerous organs, as well as irritation
of the eyes and respiratory system, skin, and mucous
membranes. Cumene is a high production volume chemical.
Chemische Eigenschaften
cumene is oxidized to its hydroperoxide, which is used to produce propene oxide. The alcohol produced is subsequently converted back to cumene over a copper-chromium oxide catalyst to be reused in the process. The advantage of this process is that cumene is easier to hydroperoxidate (more stable).
Physikalische Eigenschaften
Colorless liquid with an aromatic odor. Experimentally determined detection and recognition odor
threshold concentrations were 40 μg/m
3 (8 ppb
v) and 230 μg/m
3 (47 ppb
v), respectively (Hellman
and Small, 1974). The taste threshold concentration in water is 60 ppb (Young et al., 1996).
Verwenden
Around 98% of cumene is used in the production of phenol
and its coproduct, acetone, using cumene hydroperoxide as
chemical intermediate. However, the demand for cumene is
largely dependent on the performance of phenol’s derivatives,
which have resulted in healthy growth rates in demand for
cumene. It is also used as a starting material in the production
of acetophenone, α-methylstyrene, diisopropylbenzene, and
dicumylperoxide. Cumene is used as a thinner for paints,
lacquers, and enamels. It is also used in the manufacture of
acetophenone, methylstyrene, and other chemicals commonly
found in home cleaning products. Minor uses of cumene
include as a constituent of some petroleum-based solvents,
such as naphtha; in gasoline blending diesel fuel and highoctane
aviation fuel; and as a raw material for peroxides and
oxidation catalysts such as polymerization catalysts for acrylic
and polyester-type resins. It is also a good solvent for fats and
resins and has been suggested as a replacement for benzene in
many of its industrial applications.
Allgemeine Beschreibung
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Air & Water Reaktionen
Flammable. Insoluble in water.
Reaktivität anzeigen
Mixing CUMENE in equal molar portions with any of the following substances in a closed container caused the temperature and pressure to increase: chlorosulfonic acid, nitric acid, oleum, NFPA 1991.
Hazard
Toxic by ingestion, inhalation, and skin
absorption; a narcotic. Moderate fire risk. Eye, skin,
and upper respiratory tract irritant, and central nervous system impairment. Possible carcinogen.
Health Hazard
Narcotic action with long-lasting effects; depressant to central nervous system. Acute (short-term) inhalation exposure to cumene may cause headaches, dizziness, drowsiness, slight incoordination, and unconsciousness in humans. Cumene has a potent central nervous system (CNS) depressant action characterized by a slow induction period and long duration of narcotic effects in animals. Cumene is a skin and eye irritant. No information is available on the chronic (long-term), reproductive, developmental, or carcinogenic effects of cumene in humans. Animal studies have reported increased liver, kidney, and adrenal weights from inhalation exposure to cumene. EPA has classified cumene as a Group D, not classifiable as to human carcinogenicity.
Brandgefahr
HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
Chemische Reaktivität
Reactivity with Water: No reaction; Reactivity with Common Materials: No reaction; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.
Sicherheitsprofil
Moderately toxic by
ingestion. Mdly toxic by inhalation and skincontact. Human systemic effects by
inhalation: an antipsychotic, unspecified
changes in the sense of smell and respiratory
system. An eye and skin irritant. Potential
narcotic action. Central nervous system
depressant. There is no apparent difference
between the toxicity of natural cumene and
that derived from petroleum. See also
BENZENE and TOLUENE. Flammable
liquid when exposed to heat or flame; can
react with oxidizing materials. Violent
reaction with HNO3, oleum, chlorosulfonic
acid. To fight fKe, use foam, CO2, dry
chemical.
mögliche Exposition
Cumene is used primarily in the manufacture acetone and phenol which are widely used as solvents for paints, laquers, and varnishes and to make plastics. Cumene is used in gasoline blending and as a high-octane gasoline component. It is also found as a component in tobacco smoke.
Carcinogenicity
Cumene was not a developmental toxicant
in either rats or rabbits after exposure to levels
(1200ppm and 2300ppm, respectively) associated
with maternal toxicity.9 Most genotoxic
tests with cumene have been negative.
The LD50 for penetration of rabbit skin
was 12.3 ml/kg after 14 days.4 Contact of the
liquid with the skin causes erythema and irritation.
11 Eye contamination may produce conjunctival
irritation.
It generally is agreed that cumene has no
damaging effect on the hematopoietic system,
despite its chemical similarity to benzene.5
Furthermore, cumene is not anticipated to be
a significant carcinogenic hazard because it is
metabolically similar to toluene, a substance
that showed no carcinogenic activity in 2-year
inhalation studies.
Versand/Shipping
UN1918 Cumene, Hazard Class: 3; Labels: 3-Flammable liquid
Inkompatibilitäten
Vapor may form explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, 942 Cumene fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Air contact forms cumene hydroperoxide. Attacks rubber. May accumulate static electrical charges, and may cause ignition of its vapors.
Waste disposal
Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. All federal, state, and local environmental regulations must be observed.
(1-Methylethyl)benzol Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
