Tranylcyprominsulfat
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- CAS-Nr.
- 13492-01-8
- Bezeichnung:
- Tranylcyprominsulfat
- Englisch Name:
- Tranylcypromine Hemisulfate
- Synonyma:
- parnate;tranylcyprominesulfate;tranylcyprominesulphate;phenylcycloprominesulfate;TRANYLCYPROMINE HEMISULFATE;TRANYLCYPROMINE HEMISULFATE SALT;Tranylcypromine Sulfate (125 mg);Tranylcypromine Sulfate (1672905);1-amino-2-phenylcyclopropanesulfate;trans,d,l-2-phenylcyclopropylaminesulfate
- CBNumber:
- CB2314310
- Summenformel:
- C9H13NO4S
- Molgewicht:
- 231.27
- MOL-Datei:
- 13492-01-8.mol
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Tranylcyprominsulfat Eigenschaften
- storage temp.
- 15-25°C
- Löslichkeit
- Soluble in water; very slightly soluble in ethanol (96%) and in ether .
- Aggregatzustand
- White solid.
- Farbe
- White
- Stabilität:
- Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 3 months.
- InChIKey
- BKPRVQDIOGQWTG-FKXFVUDVSA-N
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
T |
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| R-Sätze: |
23/24/25 |
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| S-Sätze: |
36/37/39-45 |
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| RIDADR |
UN 2811 6.1/PG 2 |
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| WGK Germany |
3 |
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| RTECS-Nr. |
GZ2625000 |
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| HazardClass |
6.1(b) |
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| PackingGroup |
III |
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| HS Code |
2921490002 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H300 |
Lebensgefahr bei Verschlucken. |
Akute Toxizität oral |
Kategorie 2 |
Achtung |
![GHS hazard pictograms]() src="/GHS06.jpg" width="20" height="20" /> |
P264, P270, P301+P310, P321, P330,P405, P501 |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P301+P310 |
BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
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Tranylcyprominsulfat Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R23/24/25:Giftig beim Einatmen, Verschlucken und Berührung mit der Haut.
S-Sätze Betriebsanweisung:
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
Chemische Eigenschaften
A white or almost white, crystalline powder.
Verwenden
Monoamine oxidase inhibitor; antidepressant.
Allgemeine Beschreibung
Tranylcypromine sulfate, (±)-trans-2-phenylcyclopropylaminesulfate (Parnate), was synthesized to be an amphetamineanalog (visualize the α-methyl of amphetaminecondensed onto the β-carbon atom).It does have someamphetamine-like properties, which may be why it has moreimmediate CNS-stimulant effects than agents that act byMAO inhibition alone. For MAO inhibition, there may betwo components to the action of this agent. One is thoughtto arise because tranylcypromine has structural features (thebasic nitrogen and the quasi-π character of the α- andβ-cyclopropane carbon atoms) that approximate the transitionstate in a route of metabolism of β-arylamines. As α-and β-hydrogen atoms are removed from the normal substrateof the enzyme, the quasi-π character develops over theα,β-carbon system. Duplication of the transition state permitsextremely strong, but reversible, attachment to the enzyme.Additionally, tranylcypromine is a mechanism-based inactivator.It is metabolized by MAO, with one electron of the nitrogenpair lost to flavin. This, in turn, produces homolyticfission of a carbon–carbon bond of cyclopropane, with oneelectron from the fission pairing with the remaining lone nitrogenelectron to generate an imine (protonated) and with theother residing on a methylene carbon. Thus, a free radical isformed that reacts to form a covalent bond with the enzymeor with reduced flavin to inactivate the enzyme.
Tranylcyprominsulfat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Tranylcyprominsulfat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 122)Lieferanten
13492-01-8(Tranylcyprominsulfat)Verwandte Suche:
- tranylcyprominesulfate
- tranylcyprominesulphate
- Tranylcypromine Sulfate (125 mg)
- (1R,2S)-rel-2-Phenylcyclopropanamine Sulfate
- TRANS-2-PHENYLCYCLOPROPYLAMINE HEMISULFATE
- TRANS-2-PHENYLCYCLOPROPYLAMINE HEMISULFATE SALT
- TRANYLCYPROMINE HEMISULFATE
- TRANYLCYPROMINE HEMISULFATE SALT
- (+-)-trans-2-phenylcyclopropylaminesulfate(2:1)
- 1-amino-2-phenylcyclopropanesulfate
- 2-phenyl-cyclopropanamintrans-(+-)-cyclopropanaminsulfate(2:1)
- 2-phenyl-cyclopropylaminsulfate,trans-(+-)-cyclopropylamin(2:1)
- parnate
- phenylcycloprominesulfate
- trans,d,l-2-phenylcyclopropylaminesulfate
- rel-(1R,2S)-2-phenylcyclopropan-1-amine hemisulfate
- trans-2-Phenylcyclopropylamine hemisulfate salt CAS 236-807-1
- Tranylcypromine Sulfate (1672905)
- rans-2-Phenylcyclopropylaminehemisulfatesal
- trans-2-Phenylcyclopropanamine hemisulfate
- (1R,2S)-rel-2-Phenylcyclopropanamine Disulfate
- 13492-01-8
- 2C9H11NH2SO4
- C9H11N12H2SO4
- Biochemicals and Reagents
- BioChemical
- Enzyme Inhibitors by Enzyme
- Enzymes, Inhibitors, and Substrates
- Enzyme Inhibitors
- Monoamine oxidase inhibitor
- L to O
