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ChemicalBook > Produktkatalog >Aktive pharmazeutische Wirkstoffe (APIs) >Kreislaufsystem Drogen >Angina pectoris-Arzneimittel >Nitrendipin

Nitrendipin Produkt Beschreibung

CAS-Nr.39562-70-4
Bezeichnung:Nitrendipin
Englisch Name:Nitrendipine
Synonyma:
Deiten;nidrel;Nitrepin;baye5009;baypress;Bylotensin;bayotensin;Nitrendipin;lmethylester;NITRENDIPINE
CBNumber:CB2395104
Summenformel:C18H20N2O6
Molgewicht:360.36
MOL-Datei:39562-70-4.mol
Nitrendipin physikalisch-chemischer Eigenschaften
Schmelzpunkt:: 1580C
Siedepunkt:: 492.4°C (rough estimate)
Dichte: 1.3595 (rough estimate)
Brechungsindex: 1.5700 (estimate)
storage temp. : Store at RT
Löslichkeit: methanol: 15 mg/mL
Aggregatzustand: powder
Farbe: yellow to green
Wasserlöslichkeit: Soluble in DMSO (17.5 mg/ml), methanol (15 mg/ml), ethyl acetate, and ethanol (25 mM). Insoluble in water.
CAS Datenbank: 39562-70-4(CAS DataBase Reference)
NIST chemische Informationen: Nitrendipine(39562-70-4)
Sicherheit
Kennzeichnung gefährlicher: Xn
R-Sätze:: 20/21/22
S-Sätze:: 36
WGK Germany : 1
RTECS-Nr.: US5653000
Toxizität: LD50 in mice, rats (mg/kg): 39, 12.6 i.v.; 2540, >10000 orally (Hoffmann)

Nitrendipin Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
S-Sätze Betriebsanweisung:
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
Nitrendipine is a vasodilating, dihydropyridine calcium antagonist. Its prolonged therapeutic effect in comparison to nifedipine makes it useful in the once to twice daily treatment of hypertension.
Chemische Eigenschaften
Crystalline Solid
Originator
Bayer (W. Germany)
Verwenden
Antihypertensive;Calcium channel blocker
Verwenden
Nitrendipine is a dihydropyridine calcium channel blocker. Nitrendipine is used in the treatment of primary (essential) hypertension to decrease blood pressure. Antihypertensive.
Definition
ChEBI: A dihydropyridine that is 1,4-dihydropyridine substituted by methyl groups at positions 2 and 6, a 3-nitrophenyl group at position 4, a ethoxycarbonyl group at position 3 and a methoxycarbonyl group at position 5. It is a calcium-channel blocker used in t e treatment of hypertension.
Trademarks
Baypress (Bayer);BAYOTENSIN.
Allgemeine Beschreibung
Nitrendipine, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinecarboxylic acid methyl ethylester (Baypress), is a second-generation dihydropyridinechannel blocker of the nifedipine type. It is more selectivefor vascular smooth muscle than for myocardial tissue andserves as an effective vasodilator. The drug is used in thetreatment of mild-to-moderate essential hypertension.
Biologische Aktivität
L-type calcium channel blocker.
Nitrendipin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Ethylacetoacetat Methyl-3-aminocrotonat Methylacetoacetat 3-Nitrobenzaldehyd
Downstream Produkte
Nitrendipin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.      Global( 251)Lieferanten     
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925Abel@chembj.com CHINA 3203 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21968 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693info@tianfuchem.com CHINA 20680 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733sales@mainchem.com CHINA 32457 55
Hubei XinRunde Chemical Co., Ltd.
+8615102730682; +8618874586545
02783214688bruce@xrdchem.cn CHINA 541 55
Xiamen AmoyChem Co., Ltd
+86 (0)592-605 1114
sales@amoychem.com CHINA 6374 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 24001 58
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254
peter@hubeijusheng.com CHINA 20095 58
Accela ChemBio Inc.
(+1)-858-699-3322
(+1)-858-876-1948info@accelachem.com United States 12233 58
QUALITY CONTROL CHEMICALS INC.
(323) 306-3136
(626) 453-0409orders@qcchemical.com United States 8409 58
 
39562-70-4(Nitrendipin)Verwandte Suche:
Mexiletin EPN Pyridin-3,5-dicarbonsure Nimodipin Nitrendipin 2-(Benzylmethylamino)ethylmethyl-1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)pyridin-3,5-dicarboxylat Niludipin 2-(Benzylmethylamino)ethylmethyl-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridin-3,5-dicarboxylatmonohydrochlorid
Group horizon 3-ethyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate Lercanidipine Impurity 13 Bylotensin Deiten 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, ethyl methyl ester (9CI) Nitrepin Nitrendipin 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylic acid methyl ethyl ester Ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 5-ethyl 3-methyl ester 4-(3-Nitrophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid 3-ethyl 5-methyl ester lmethylester nidrel ylmethylester ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(meta-nitrophenyl)-3,5-pyridinedicarboxylate 1,4-DIHYDRO-2,6-DIMETHYL-4-(3'-NITROPHENYL)-3,5-PYRIDINEDICARBOXYLIC ACID ETHYL METHYL ESTER 1,4-DIHYDRO-2,6-DIMETHYL-4-(3-NITROPHENYL)-3,5-PYRIDINEDICARBOXYLIC ACID ETHYL METHYL ESTER NITRENDIPINE >95% CA2+ CHANNEL BLOCKER, NITRENDIPINE EPN(CRM STANDARD) (NITROPHENYLPYRIDINE ANALOGUE) EPN(CRM STANDARD) NITRENDIPINE IMPURITY AETHYL METHYL-2,6-DIMETHYL-4-(3-NITROPHENYL) PYRIDINE-3,5-DICARBOXYLATE NITRENDIPINE MM(CRM STANDARD) 3-ethyl 5-Methyl (4R)-2,6-diMethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate Lercanidipine Ethyl Methyl Ester IMpurity (IMpurity 5) 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester Nitrendipine for peak identification (RS)-Methylethyl-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate 39562-70-4 C18H20N2O6 Calcium Channel Modulators Cell Biology Cell Signaling and Neuroscience BioChemical Ion Channels Inhibitors and Activators Voltage-gated Ion Channels NITRENDIPINE 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylicacidethy baye5009 bayotensin baypress ethylmethyl1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxy Pharmaceutical Intermediates & Fine Chemicals Pharmaceuticals Calcium channel Ion Channels API Pharmaceutical intermediate Pharmaceutical intermediates
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