SUCCINYL COENZYME A SODIUM SALT

SUCCINYL COENZYME A SODIUM SALT Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-Sätze Betriebsanweisung:

S22:Staub nicht einatmen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

Beschreibung

Succinyl-coenzyme A (succinyl-CoA) is an intermediate in the citric acid cycle. It is converted to succinate, which is a metabolic intermediate with various biological activities. Succinyl-CoA is required, with glycine, to form δ-aminolevulinic acid in the first step of porphyrin and heme synthesis. Succinyl-CoA deficiency, caused by vitamin B₁₂ deficiency can disrupt heme and energy production, leading to neuromotor dysfunction.

Verwenden

Succinyl coenzyme A sodium salt has been used:

• for the nonenzymatic succinylation of lysine in vitro,
• as a substrate for adipic acid biosynthesis in recombinant E. coli
• in isocitrate dehydrogenase (ICDH)?treatment for the succinylation of proteins
• as a substrate to study the specificity and kinetics of enzymes such as acetate:succinate CoA-transferase and 5-aminolevulinate synthase (ALA synthase)

läuterung methode

If it should be purified further, then it should be dissolved in H2O (0.05g/mL) adjusted to pH 1 with 2M H2SO4 and extracted several times with Et2O. Excess Et2O is removed from the aqueous layer by bubbling N2 through it and is stored frozen at pH 1. When required, the pH should be adjusted to 7 with dilute NaOH and used within 2 weeks (samples should be frozen). Succinyl coenzyme A is estimated by the hydroxamic acid method [Hersch & Jencks J Biol Chem 242 3468 1967]. It is more stable in acidic than in neutral aqueous solutions, but neutral solutions can be stored at –15o with negligible decomposition. [Jordan & Laghai-Newton Methods Enzymol 123 435 1986, Beilstein 26 III/IV 3666.]

SUCCINYL COENZYME A SODIUM SALT Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

SUCCINYL COENZYME A SODIUM SALT Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418684 +8618949823763	sales@tnjchem.com	China	25363	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
Shanghai Yingxin laboratory equipment Co., Ltd	021-021-59178156 15300768757	359382369@qq.com	China	10367	58
Chengdu HuaXia Chemical Reagent Co. Ltd	400-1166-196 13458535857	cdhxsj@163.com	China	13358	58
Shanghai Macklin Biochemical Co.,Ltd.	15221275939 15221275939	shenlinxing@macklin.cn	China	15878	55
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
Hubei Xinyang Medical Technology Co., Ltd	15347293736 15347293736	2853117764@qq.com	China	8854	58

108347-97-3()Verwandte Suche:

---

• SUCCINYL COENZYME A SODIUM SALT
• succinyl coenzyme A sodium
• coenzyme A succinyl derivative, trisodium salt
• Succinyl CoA, Li-salt
• Succinyl coenzyme A sodium salt >=85%
• Coenzyme A,S-(hydrogen butanedioate),sodium salt
• Coenzyme A, S-(hydrogenbutanedioate), sodium salt (9CI)
• 108347-97-3
• C25H38N7Na2O19P3S
• Metabolic Libraries
• Lipid Library
• Metabolomics
• BioChemical
• Aminolevulinate synthase, 5-Saturated fatty acids and derivatives
• Cofactors
• Enzymes, Inhibitors, and Substrates
• Esters
• Fatty acyl CoAsMetabolic Pathways
• Lipid Library
• LipidMetabolomics
• Metabolic Libraries
• Metabolites and Cofactors on the Metabolic Pathways Chart
• Substrates by Enzyme
• Acyl Transfer ReagentsEnzyme Substrates