alpha-Arbutin

alpha-Arbutin Struktur
84380-01-8
CAS-Nr.
84380-01-8
Englisch Name:
alpha-Arbutin
Synonyma:
Alpha Arbutin Powder;Α-ARBUTIN;α-Arbutin;a-Arbutin;4-hydroquinone-alpha-d-glucopyranoside;(2R,3S,4S,5R,6S)-2-(HYDROXYMETHYL)-6-(4-HYDROXYPHENOXY)TETRAHYDROPYRAN-3,4,5-TRIOL;(2R,3S,4S,5R,6R)-2-(Hydroxymethyl)-6-(4-hydroxyphenoxy)tetrahydro-2H-pyran-3,4,5-triol;LGB-AA;Alpha bear;alpha-arbutin
CBNumber:
CB3855311
Summenformel:
C12H16O7
Molgewicht:
272.25
MOL-Datei:
84380-01-8.mol

alpha-Arbutin Eigenschaften

Schmelzpunkt:
195-196°C
Siedepunkt:
561.6±50.0 °C(Predicted)
Dichte
1.556±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
Löslichkeit
DMSO (Slightly), Methanol (Slightly)
Aggregatzustand
Solid
pka
10.10±0.15(Predicted)
Farbe
White to Off-White
BRN 
89675
InChI
InChI=1/C12H16O7/c13-5-8-9(15)10(16)11(17)12(19-8)18-7-3-1-6(14)2-4-7/h1-4,8-17H,5H2/t8-,9-,10+,11-,12+/s3
InChIKey
BJRNKVDFDLYUGJ-ZIQFBCGOSA-N
SMILES
O(C1C=CC(O)=CC=1)[C@@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O |&1:8,9,10,12,14,r|
CAS Datenbank
84380-01-8(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
WGK Germany  3
HS Code  2938.90.0000
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitsschädlich bei Verschlucken. Akute Toxizität oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizität (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P270 Bei Gebrauch nicht essen, trinken oder rauchen.
P271 Nur im Freien oder in gut belüfteten Räumen verwenden.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P301+P312 BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.
P302+P352 BEI BERÜHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckmäßig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen.
P304+P340 BEI EINATMEN: Die Person an die frische Luft bringen und für ungehinderte Atmung sorgen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.
P330 Mund ausspülen.
P332+P313 Bei Hautreizung: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen.
P337+P313 Bei anhaltender Augenreizung: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen.
P362 Kontaminierte Kleidung ausziehen und vor erneutem Tragen waschen.

alpha-Arbutin Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Arbutin is naturally found in plant sources such as Bearberry, Cranberry and Mulberry, which essentially prevents the formation of melanin (the pigment that creates skin colour). The chemically synthesised version of this plant extract is known as Alpha Arbutin which is used as a topical skin brightening agent to treat sun spots, pigmentation and scars caused by sun damage and breakouts. It also has antioxidant properties, which protect the skin from potential sun damage. Along with Retinol, it is a fairly common ingredient in anti-ageing products to treat age spots, fine lines and wrinkles. alpha-Arbutin-1.jpg

Chemische Eigenschaften

alpha-Arbutin is White Solid

Verwenden

alpha-Arbutin is a component used in the skin-whitening cosmetics.

Definition

Alpha arbutin, also called Hydroquinone β-D-glucopyranoside, is a naturally occurring antioxidant and skin brightener that is naturally found in the bearberry plant. It reduces melanin formation, improving the appearance of age spots, freckles, melasma, and post-inflammatory pigmentation.

benefits

Ensures an even skin tone after only one month;Reduces the degree of skin tanning after UV exposure;Helps to minimize the appearance of liver spots.

Biologische Funktion

Alpha arbutin acts as a tyrosinase competitive inhibitor and also slows melanosome maturation (the organelles that synthesize and store melanin or pigment).3 This is significant because it works on two different mechanisms of pigmentation. Melanin is derived from the amino acid tyrosine and this conversion is regulated by the enzyme tyrosinase. Alpha arbutin is similar in structure to tyrosine, which fits into tyrosinase, needed for melanogenesis. This means that alpha arbutin is reversibly competing with tyrosine for a spot on the enzyme and not inhibiting cell viability, so therefore is not cytotoxic. By targeting tyrosinase, the rate-limiting enzyme in melanin formation, as well as slowing production of the organelles that produce melanin, alpha arbutin is a potent skin brightening agent.

Allgemeine Beschreibung

α-Arbutin is a glycosylated hydroquinone and an anomer of naturally occurring arbutin. It is a potent inhibitor of tyrosinase, a vital enzyme involved in epidermal melanin biosynthesis. α-Arbutin finds extensive application as a powerful skin-lightening agent in cosmetic industries.

Mechanism of action

Alpha arbutin is frequently marketed as a safer alternative to hydroquinone (a popular skin-lightening ingredient that has been banned in Europe and Australia). It has similar results in brightening skin but without the dangerous bleaching process. Instead, it reduces skin’s pigment production by suppressing the enzymes that stimulate melanin. This also slows down the process by which UV light causes pigmentation, so it both prevents and treats pigmentation issues.

Nebenwirkungen

Alpha arbutin is an active compound. Using too many active agents together can cause harshness to your skin.
For sensitive skin, using too much product containing alpha arbutin can cause a burning sensation on your face or skin.
Using moisturisers just after applying alpha arbutin cream or gel may not work well on your skin. It is a light compound which does not absorb well into the skin if topped over a moisturiser.
Alpha arbutin side effects occur when applied on cracked skin. It is suitable for topical use but when it comes in contact with an exposed wound, it causes unbearable irritation.

alpha-Arbutin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


alpha-Arbutin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 594)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Huzhou Haipu Chemical Co.,Ltd
+86-0572-+86-0572-2526078 +8613757061525
xatyang@acetylacetone.net China 16 58
Henan Bao Enluo International TradeCo.,LTD
+86-17331933971 +86-17331933971
deasea125996@gmail.com China 2503 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418679 +86-18949832763
info@tnjchem.com China 2989 55
ZhenYiBio Technology Inc
+8615309206328
alexxue@zhenyibio.com China 299 58
Hebei Endun Biological Technology Co. LTD
+86-8615932657220 +86-15932657220
sales05@hebeiendun.cn China 300 58
Sinoway Industrial co., ltd.
0592-5800732; +8613806035118
xie@china-sinoway.com China 992 58
LEAP CHEM CO., LTD.
+86-852-30606658
market18@leapchem.com China 24738 58
Hebei Mojin Biotechnology Co., Ltd
+8613288715578
sales@hbmojin.com China 12456 58
Hebei Yime New Material Technology Co., Ltd.
+86-66697723 +86-17703311139
admin@china-yime.com China 563 58
Anhui Yiao New Material Technology Co., Ltd
+86-199-55145978 +8619955145978
sales8@anhuiyiao.com China 253 58

84380-01-8()Verwandte Suche:


  • alpha-arbutin
  • Hydroquinone O-α-D-Glucopyranoside
  • 4-Hydroxyphenyl a-D-glucopyranoside
  • 4-hydroxyphenyl alpha-D-glucopyranoside
  • Alpha bear
  • α-arbutin 84380-01-8
  • (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol
  • LGB-AA
  • Alpha Arbutin 98%
  • 4-hydroxyphenyl-D-lucopyranoside
  • alpha-Arbutoside
  • α-D-Glucopyranoside, 4-hydroxyphenyl
  • a-D-Glucopyranoside, 4-hydroxyphenyl
  • Skin whitening alpha-arbutin
  • Alpha-Arbutin Skin Whitening Alpha Arbutin Powder
  • Arbutin /Alpha Arbutin
  • Alpha-Arbutin CAS 84380-01-8 4-Hydroquinone-Alpha-D-Glucopyranoside
  • alpha-ArbutinQ: What is alpha-Arbutin Q: What is the CAS Number of alpha-Arbutin
  • 4-hydroquinone-alpha-d-glucopyranoside
  • a-Arbutin
  • (2R,3S,4S,5R,6S)-2-(HYDROXYMETHYL)-6-(4-HYDROXYPHENOXY)TETRAHYDROPYRAN-3,4,5-TRIOL
  • (2R,3S,4S,5R,6R)-2-(Hydroxymethyl)-6-(4-hydroxyphenoxy)tetrahydro-2H-pyran-3,4,5-triol
  • Alpha Arbutin Powder
  • Α-ARBUTIN
  • α-Arbutin
  • Alpha-Arbutin For Skin Care
  • Manganese chloride 7773-01-5
  • alphTXB-Arbutin
  • 4-Hydroxyphenyl α-D-Glucopyranoside
  • 84380-01-8
  • C12H17O7
  • Plant extract
  • Aromatics
  • Carbohydrates & Derivatives
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • 84380-01-8
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