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CHYMOSTATIN

CHYMOSTATIN Struktur
9076-44-2
CAS-Nr.
9076-44-2
Englisch Name:
CHYMOSTATIN
Synonyma:
AIDS-028443;CHYMOSTATIN;CHYMOSTATIN USP/EP/BP;ChyMostatin research grade;ACRYLAMIDE PROTEOMICS GRADE;Chymostatin from Microbial Source;chymostatin, mixture of components A;N-[-N-ALPHA-CARBONYL-CPD-X-PHE-AL]-PHE;Chymostatin - CAS 9076-44-2 - Calbiochem;CHYMOSTATIN, MIXTURE OF COMPONENTS A, B AND C
CBNumber:
CB4161466
Summenformel:
C92H121N21O18
Molgewicht:
1809.08
MOL-Datei:
9076-44-2.mol
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CHYMOSTATIN Eigenschaften

Schmelzpunkt:
205 °C
storage temp. 
-20°C
Löslichkeit
DMSO: 10 mM Stock solutions stable for months at −20 °C.
Aggregatzustand
White to slightly yellow solid or powder
Farbe
White or off-white
Stabilität:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

Sicherheit

Kennzeichnung gefährlicher Xi
R-Sätze: 36/37/38
S-Sätze: 22-24/25-36-26
WGK Germany  3
RTECS-Nr. GC3047700
F  10-21

CHYMOSTATIN Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-Sätze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.

Beschreibung

Chymostatin is a bioactive peptide of microbial origin that acts as a protease inhibitor with selectivity for chymotryptase-like serine proteases. It potently inhibits chymotrypsin and chymase (Ki = 9.36 and 13.1 nM, respectively) while less effectively blocking the activity of cathepsins, papain, and leukocyte elastase. It is without effect on trypsin, thrombin, plasmin, pepsin, and kallikrein.

Verwenden

Chymostatin is a specific inhibitor of α-, β-, γ-, and δ-chymotrypsin.

Allgemeine Beschreibung

Chymostatin is a mixture of three components, A, B, and C. The component A being N-[((S)-1-carboxy-2-phenylethyl)-carbamoyl]-α-[2-iminohexahydro-4(S)-pyrimidyl]-L-glycyl-L-leucyl-phenylalaninal. The other two components B and C differ in that the L-leucyl residue is substituted by L-valine and L-isoleucine, respectively.

CHYMOSTATIN Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

CHYMOSTATIN Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 136)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Alpha Biopharmaceuticals Co., Ltd 		+86-411-39042497 +8613921981412
 sales@alphabiopharm.com China 886 58
Hubei xin bonus chemical co. LTD 		86-13657291602
linda@hubeijusheng.com CHINA 22968 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427
 sales@conier.com China 49390 58
career henan chemical co 		+86-0371-86658258 15093356674;
 factory@coreychem.com China 29826 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250
 1026@dideu.com China 29220 58
Shanghai Acmec Biochemical Technology Co., Ltd. 		+undefined18621343501
 product@acmec-e.com China 33349 58
Aladdin Scientific 		+1-833-552-7181
sales@aladdinsci.com United States 57511 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131981 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788
 jkinfo@jkchemical.com China 96815 76
Alabiochem Tech.Co., Ltd. 0512-58900862 400-0707518
 sales@alabiochem.com China 995 59

9076-44-2()Verwandte Suche:

Trypsin Inhibitor Aluminiumtris(2,4-pentandionato-O,O') Methylisocyanacetat (Pentan-2,4-dionato-O,O')silber Ethylisocyanacetat (p-Toluolsulfonyl)methylisocyanid Benzylisocyanid 2-Methylpropylisocyanid N-Butylisocyanid (Ethylenbis(nitrilomethylidyn)-2,2'-diphenolato)cobalt(II) 1,1,3,3-Tetramethylbutylisocyanat Kupfer(II)-4-oxopent-2-en-2-olat Phenylselenol Tris(2,2,6,6-tetramethylheptan-3,5-dionato-O,O')europium Chymotrypsin L-2-(2-Amino-1,4,5,6-tetrahydro-4-pyrimidinyl)-N-[[(α-carboxyphenethyl)amino]carbonyl]glycyl-N-(α-formylphenethyl)-L-isoleucinamid, stereoisomer L-2-(2-Amino-1,4,5,6-tetrahydro-4-pyridyl)-N-[[(1-carboxyphenethyl)amino]carbonyl]glycyl-N-(1-formylphenethyl)-L-valinamid, Stereoisomer L-2-(2-Amino-1,4,5,6-tetrahydro-4-pyrimidinyl)-N-[[(α-carboxyphenethyl)amino]carbonyl]glycyl-N-(α-formylphenethyl)-L-leucinamid, stereoisomer
  • (S)-1-CARBOXY-2-PHENYLETHYL]-CARBAMOYL-ALPHA-[2-AMIDOHEXAHYDRO-4(S)-PYRIMIDYL]-(S)-GLYCYL-[A = LEU; B = VAL; OR C = ILE]-PHENYLALANINAL
  • (S)-1-CARBOXY-2-PHENYLETHYL)-CARBAMOYL-ALPHA-[2-IMINOHEXAHYDRO-4(S)-PYRIMIDYL]-(S)-GLYCYL-X-PHENYLALANINAL
  • [(S)-1-CARBOXY-2-PHENYLETHYL]-CARBAMOYL-ALPHA-[2-IMINOHEXAHYDRO-4(S)-PYRIMIDYL]-(S)-GLY-X-PHE-AL
  • N-[-N-ALPHA-CARBONYL-CPD-X-PHE-AL]-PHE
  • CHYMOSTATIN
  • AIDS-028443
  • ChyMostatin research grade
  • ACRYLAMIDE PROTEOMICS GRADE
  • Chymostatin from Microbial Source
  • chymostatin, mixture of components A
  • CHYMOSTATIN, MIXTURE OF COMPONENTS A, B AND C
  • n-(nα-carbonyl-cpd-x-phe-al)-phe (cpd = capreomycidine) (capreomycidine = [s,s]-α-(2-iminohexahydro-4-pyrimidyl)glycine)
  • (2S)-2-[[(1S)-1-(2-Amino-3,4,5,6-tetrahydropyrimidin-4-yl)-2-[[(2S)-4-methyl-1-oxo-1-[[(2S)-1-oxo-3-phenylpropan-2-yl]amino]pentan-2-yl]amino]-2-oxoethyl]carbamoylamino]-3-phenylpropanoic acid
  • Chymostatin - CAS 9076-44-2 - Calbiochem
  • N-[-Nα-carbonyl-[S,S]-α-(2-iminohexahydro-4-pyrimidyl)glycine-Val-Phe-al]-Phe
  • CHYMOSTATIN USP/EP/BP
  • N-(Nα-Carbonyl-Cpd-X-Phe-al)-Phe (Cpd = capreomycidine) (capreomycidine = [S,S]-α-(2-Iminohexahydro-4-pyrimidyl)glycine)
  • 9076-44-2
  • C31H41N7O6
  • C30H39N7O6
  • C31H41O6N7
  • A to C
  • Cathepsin B
  • BioChemical
  • Biochemicals and Reagents
  • Enzyme Inhibitors
  • Enzymes, Inhibitors, and Substrates
  • Enzyme Inhibitors by Enzyme
  • Enzyme Inhibitors by Type
  • Substrate Analogs
  • peptides
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