3,3'-Dihydroxy-4,4'-methylendi-2-naphthoesure

3,3'-Dihydroxy-4,4'-methylendi-2-naphthoesure Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R48:Gefahr ernster Gesundheitsschäden bei längerer Exposition.
R41:Gefahr ernster Augenschäden.
R37/38:Reizt die Atmungsorgane und die Haut.
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.

S-Sätze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S22:Staub nicht einatmen.

Chemische Eigenschaften

Pamoic acid is yellow to yellow-green crystalline powder

Verwenden

Pamoic acid is used in preparation of repository derivatives of medicinal agents, used in pharmacology to increase the solubility of a drug in water.

Allgemeine Beschreibung

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Biologische Aktivität

(1)Pamoic acid can inhibit Cas9 endonuclease activity. It effectively blocks bacterial or mammalian genome editing mediated by SpyCas9, SauCas9 or BE4 base editors at multiple endogenous gene loci. In addition, pamoic acid displays substrate competitive and PAM binding site occupancy mechanisms that selectively inhibit linear DNA cleavage compared to Cas9 cleavage of superhelical DNA. Importantly, pamoic acid pharmacologically modulates Cas9-mediated genome editing in mice.
(2)GPR35 activation by Pamoic acid may increase the phosphorylation of ERK1/2, which in turn initiates an anti-inflammatory signal by suppressing NF-κB-dependent inflammatory genes.

Sicherheitsprofil

Poison by intraperitoneal route. An eye irritant. When heated to decomposition it emits acrid smoke and irritating fumes.

3,3'-Dihydroxy-4,4'-methylendi-2-naphthoesure Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

3,3'-Dihydroxy-4,4'-methylendi-2-naphthoesure Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971	deasea125996@gmail.com	China	2472	58
Taizhou Creating Bio-pharm co., ltd.	0576-88827176; +8613586099526	post@creatingbiopharm.com	China	223	58
Shaanxi Xianhe Biotech Co., Ltd	+86-17709210191; +8617709210191	Jerry@xhobio.com	China	883	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21612	55
Shanghai Time Chemicals CO., Ltd.	+86-021-57951555 +8617317452075	jack.li@time-chemicals.com	China	1803	55
Chembon Pharmaceutical Co., Ltd.	+86-28-8425-2981		CHINA	722	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29846	58
Jinan Chenghui-Shuangda Chemical Co.,Ltd	+86-531-58897082	ericqiao@jnchsd.com	CHINA	158	58

130-85-8(3,3'-Dihydroxy-4,4'-methylendi-2-naphthoesure)Verwandte Suche:

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• PAMOIC ACID
• EMBIONIC ACID
• 2-Naphthalenecarboxylic acid, 4,4-methylenebis3-hydroxy-
• 1,1'-methylene-bis(2-hydroxy-3-naphthoic acid)
• PAMOIC ACID pure
• 1,1μ-Methylene-bis(2-hydroxy-3-naphthoic acid), 4,4μ-Methylenebis(3-hydroxy-2-naphthoic acid), Embonic acid
• Bis(2-hydroxy-3-carboxy-1-naphthyl)methane
• Pamoic Acid (250 mg)
• PamoicAcid98%
• 4,4'-Methylenebis[3-hydroxy-
• PaMoic aci
• PaMoic acid >=97.0% (T)
• PalMer acid
• 3,3-dihydroxy-4,4-methylenedi(2-naphthoic acid)
• Embonic acid~4,4-Methylenebis(3-hydroxy-2-naphthoic acid)
• PAMOIC ACID FREE ACID
• 2,2'-DIHYDROXY-1,1'-DINAPHTHYLMETHANE 3,3'-DICARBOXYLIC ACID
• 4-[(3-CARBOXY-2-HYDROXY-NAPHTHALEN-1-YL)METHYL]-3-HYDROXY-NAPHTHALENE-2-CARBOXYLIC ACID
• 4,4'-METHYLENE BIS-(3-HYDROXY-2-NAPTHOIC ACID)
• 4-4'-METHYLENE-BIS-[2-HYDROXY-3-NAPHTHOIC ACID]
• 4,4'-METHYLENEBIS(3-HYDROXY-2-NAPHTHALENECARBOXYLIC ACID)
• 4,4-METHYLENEBIS[3-HYDROXY-2-NAPHTHALENECARBOXYLIC ACID]
• 4,4-METHYLENEBIS(3-HYDROXY-2-NAPHTHOIC ACID)
• 4,4’-methylenebis(3-hydroxy-2-naphthalenecarboxylicaci
• 4,4’-methylenebis(3-hydroxy-2-naphthoicaci
• 4,4’-methylenebis[3-hydroxy-2-naphthalenecarboxylicaci
• 4-[(3-carboxylato-2-hydroxy-1-naphthalenyl)methyl]-3-hydroxy-2-naphthalenecarboxylate
• Pamic acid
• PamoicAcid>
• Pamoic acid, 99%,
• Pamoic Acid (1493000)
• EMBONIC ACID
• Pamoic
• Embonic acid, Pamoic acid
• 4-[(3-carboxy-2-hydroxy-1-naphthyl)methyl]-3-hydroxy-naphthalene-2-carboxylic acid
• 4,4'-Methylenebis(3-hydroxy-2-naphthoic acid)
• 2-Naphthalenecarboxylic acid, 4,4'-methylenebis[3-hydroxy-
• 3,3'-dihydroxy-4,4'-methylenedi(2-naphthoic acid)
• Pamuric acid
• 130-85-8
• C23H16O6
• Organic Building Blocks
• C13 to C42+
• Carboxylic Acids
• Carbonyl Compounds
• Building Blocks
• Antiparasitic Agents
• Bioactive Small Molecules
• Biochemicals and Reagents
• Building Blocks
• C13 to C42+
• Carbonyl Compounds
• Carboxylic Acids
• Cell Biology
• Chemical Synthesis
• Fatty Acids and conjugates
• Fatty Acyls
• Lipids