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Lup-20(29)-en-28-olsure, 3-Hydroxy-, (3β)- Produkt Beschreibung

Betulinic acid  Struktur
472-15-1
CAS-Nr.
472-15-1
Bezeichnung:
Lup-20(29)-en-28-olsure, 3-Hydroxy-, (3β)-
Englisch Name:
Betulinic acid
Synonyma:
MAIRIN;ALS-357;Platanol;Betulinic;Ccris 6748;Nsc 113090;Nsc 677578;Gratiolone;Melaleucin;BETULIC ACID
CBNumber:
CB4667160
Summenformel:
C30H48O3
Molgewicht:
456.7
MOL-Datei:
472-15-1.mol

Lup-20(29)-en-28-olsure, 3-Hydroxy-, (3β)- Eigenschaften

Schmelzpunkt:
295-298 °C (dec.)(lit.)
alpha 
D25 +7.5° (c = 0.37 in pyridine)
Brechungsindex
7.8 ° (C=0.9, Pyridine)
storage temp. 
Store at +4°C
Aggregatzustand
neat
Optische Aktivität
[α]20/D +7.8°, c = 0.9 in pyridine
Merck 
14,1190
InChIKey
QGJZLNKBHJESQX-FZFNOLFKSA-N
CAS Datenbank
472-15-1(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher Xi
S-Sätze: 24/25
WGK Germany  3
HS Code  29181985

Lup-20(29)-en-28-olsure, 3-Hydroxy-, (3β)- Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften

colorless Needles

Verwenden

antineoplastic

Verwenden

Betulinic Acid is a natural pentacyclic triterpenoid. Betulinic Acid displays anti-inflammatory and anti-HIV activity. Betulinic Acid selectively induces apoptosis in tumor cells by directly activati ng the mitochondrial pathway of apoptosis through a p53- and CD95-independent mechanism. Betulinic Acid also exhibits TGR5 agonist activity

Definition

ChEBI: A pentacyclic triterpenoid that is lupane having a double bond at position 20(29) as well as 3beta-hydroxy and 28-carboxy substituents. It is found in the bark and other plant parts of several species of plants including Syzygium cla iflorum. It exhibits anti-HIV, antimalarial, antineoplastic and anti-inflammatory properties.

Biologische Aktivität

Natural triterpenoid that displays anti-HIV and antitumor activity. Induces the production of reactive oxygen species (ROS) and activates NF- κ B. Exhibits TRG5 agonist activity (EC 50 = 1.04 μ M).

Anticancer Research

This compound is a pentacyclic triterpene obtained from Betula and Zizyphus species,which shows selective cytotoxicity against human melanoma cells (Shoeb2006). It generates reactive oxygen species, activates MAPK cascade, inhibitstopoisomerase I, inhibits angiogenesis, modulates pro-growth transcriptionalactivators, modulates the activity of aminopeptidase-N, and thereby inducesapoptosis in cancer cells (Desai et al. 2008; Fulda 2008).

Lup-20(29)-en-28-olsure, 3-Hydroxy-, (3β)- Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Lup-20(29)-en-28-olsure, 3-Hydroxy-, (3β)- Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 247)Lieferanten
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
NanJing Spring & Autumn Biological Engineering CO., LTD.
13815411950
0086-25-83337318 sale03@cqherb.com CHINA 354 58
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 sales@capotchem.com China 19918 60
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3194 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21714 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20672 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32447 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30002 58
Chengdu Biopurify Phytochemicals Ltd.
18080483897
maggie@biopurify.com CHINA 2258 58
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768
sales@dolonchem.com CHINA 2972 58

472-15-1(Lup-20(29)-en-28-olsure, 3-Hydroxy-, (3β)-)Verwandte Suche:


  • 3-B-HYDROXY-LUPA-20(30)-ENE 28-OIC ACID
  • BETULINIC ACID
  • BETULIC ACID
  • MAIRIN
  • LUP-20(29)-EN-28-OIC ACID, 3-HYDROXY-, (3B)-
  • Lup-20(29)-en-28-oic acid, 3-hydroxy-, (3beta)-
  • BETULINIC ACID, TECH., 90%
  • BETULICACID: LUP-20(29)-EN-28-OICACID, 3-HYDROXY-, (3B)-,
  • Betulinic
  • 3β-hydroxy-20(29)-lupaene-28-oic acid
  • BETULINIC ACID(P)
  • Lup-20(29)-en-28-oic acid, 3-hydroxy-, (3β)-
  • BETULINIC ACID hplc
  • BETULINIC ACID WITH HPLC
  • Betulinic Acid(98%)
  • Ccris 6748
  • Einecs 207-448-8
  • Lup-20(29)-en-28-oic acid, 3beta-hydroxy- (8ci)
  • Nsc 113090
  • Nsc 677578
  • (+)-(3β)-3-Hydroxylup-20(29)-en-28-oicacid
  • Lupatic Acid
  • ALS-357
  • Gratiolone
  • Melaleucin
  • Platanol
  • Platanolic acid
  • 3β-hydroxy-lup-20(29)-ene-28-oicacid
  • 3BETA-HYDROXY-20(29)-LUPENE-28-OIC ACID
  • 3BETA-HYDROXY-20(29)-LUPAENE-28-OIC ACID
  • 3B-HYDROXY-20(29)-LUPENE-28-OIC ACID
  • (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-hydroxy-5a,5b,8,8,11a-pentaMethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylic acid
  • Betulinic acid technical grade, 90%
  • Birch bark extract/β-Amyrin/betulinic acid
  • Top Quality Betulinic Acid 98% HPLC 472-15-1
  • Betulinic acid 472-15-1
  • 472-15-1
  • 471-15-1
  • Chemopreventive Agents
  • Cancer Research
  • BioChemical
  • Anti-proliferative Agents
  • -
  • Pentacyclic Triterpenes
  • Tri-Terpenoids
  • sy
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • Antineoplastic
  • natural product
  • Inhibitors
  • Triterpenoids
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