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Fibrinogene Produkt Beschreibung

HUMAN FIBRINOGEN Struktur
9001-32-5
CAS-Nr.
9001-32-5
Bezeichnung:
Fibrinogene
Englisch Name:
HUMAN FIBRINOGEN
Synonyma:
C00393;factor i;factor 1;Parenogen;FIBRINOGEN;fibrinogens;Fibrinogen HUMAN FIBRINOGEN;FIBRINOGEN TYPE I;BOVINE FIBRINOGEN
CBNumber:
CB4683502
Summenformel:
C6H14O6
Molgewicht:
182.17176
MOL-Datei:
9001-32-5.mol

Fibrinogene Eigenschaften

storage temp. 
-20°C
Löslichkeit
0.9% NaCl: soluble
Aggregatzustand
powder
Farbe
white
EPA chemische Informationen
Fibrinogens (9001-32-5)

Sicherheit

Kennzeichnung gefährlicher B
WGK Germany  3
10-21
TSCA  Yes

Fibrinogene Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften

White or grayish amorphous substance.

Verwenden

Diagnostic aid (vascular patency); radioactive agent.

Definition

A sterile fraction of normal human blood plasma, dried from the frozen state. In solution, it has the property of being converted into insoluble fibrin when thrombin is added. It is an essential factor in the blood-clotting mechanism.

läuterung methode

A likely impurity is plasminogen. It is purified by glycine precipitation [Mosesson & Sherry Biochemistry 5 2829 1966] to obtain fractions 1-2, then further purified [Blomb.ck & Blomb.ck Arkiv Kemi 10 415 1956] and contaminating plasminogen is removed by passage through a lysine-Sepharose column. Such preparations are at least 95% clottable as determined by Mosesson and Sherry's method (above ref.) in which the OD280 is measured before and after clotting with 5 Units/mL of thrombin (> 3000U/mg). All fibrinogen preparations are treated with calf intestinal alkaline phosphatase to convert any fibrinogen peptide-AP to fibrinogen peptide-A by removing serine-bound phosphate. Solutions are then lyophilised and stored at -20o. [Higgins & Shafer J Biol Chem 256 12013 1981.] It is sparingly soluble in H2O. Aqueous solutions are viscous with isoelectric point at pH 5.5. It is readily denatured by heating above 56o or by chemical agents, e.g. salicylaldehyde, naphthoquinone sulfonates, ninhydrin or alloxan. [Edsall et al. J Am Chem Soc 69 2731 1947, Purification: Cama et al. Naturwissenschaften 48 574 1961, Lorand & Middlebrook Science 118 515 1953, cf. Fuller in Methods Enzymol 163 474 1988.] For plasminogen-deficient fibrinogen from blood plasma, the anticoagulated blood is centrifuged and the plasma is frozen and washed with saline solution. It is treated with charcoal, freeze-thawed and dialysed versus Tris/NaCl buffer. [Maxwell & Nikel Biochemical Preparations 12 16 1968.]

Fibrinogene Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Fibrinogene Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 126)Lieferanten
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Amadis Chemical Company Limited
0086-571-89925085
0086-571-89925065 sales@amadischem.com China 132148 58
Shanghai Baoman Biotechnology Co., Ltd. 021-62130998
baomanbio@163.com China 60 55

9001-32-5(Fibrinogene)Verwandte Suche:


  • Fibrinogen from Bovine, fraction I
  • Fibrinogen from bovine plasma,Factor I
  • Fibrinogen froM huMan
  • human fibrinogen dried
  • Parenogen
  • FIBRINOGEN, HUMAN PLASMA
  • FIBRINOGEN, MOUSE PLASMA
  • FIBRINOGEN, PIG PLASMA
  • FIBRINOGEN, PLASMINOGEN-DEPLETED, HUMAN
  • FIBRINOGEN, PLASMINOGEN-DEPLETED, HUMAN PLASMA
  • FIBRINOGEN, RAT PLASMA
  • FIBRINOGEN, DOG PLASMA
  • FIBRINOGEN FRACTION 1
  • FIBRINOGEN, FRACTION 1, BOVINE
  • FIBRINOGEN, CAT PLASMA
  • FIBRINOGEN, SALMON
  • FIBRINOGEN, SHEEP PLASMA
  • FIBRINOGEN TYPE I
  • FIBRINOGEN TYPE III
  • FIBRINOGEN TYPE I-S, BOVINE
  • FIBRINOGEN TYPE IV, BOVINE
  • COAGULATION FACTOR I
  • COAGULATION FACTOR I, BOVINE
  • COAGULATION FACTOR I, HUMAN
  • BOVINE FIBRINOGEN
  • Blood coagulation factor I
  • FIBRINOGEN (BOVINE) (FRACTION 1)
  • FIBRINOGEN FROM PIG PLASMA
  • FIBRINOGEN, HUMAN (FRACTION I) FROM*HUMA N PLASMA
  • FIBRINOGEN, HUMAN TYPE III FROM HUMAN*PL ASMA
  • FIBRINOGEN TYPE IV: FROM BOVINE PLASMA
  • FIBRINOGEN (FRACTION I) FROM CAT PLASMA
  • FIBRINOGEN FROM SHEEP PLASMA
  • FIBRINOGEN FROM GUINEA PIG PLASMA
  • FIBRINOGEN AUS HUMANPLASMA*
  • FIBRINOGEN FROM RAT PLASMA
  • FIBRINOGEN FROM BABOON PLASMA
  • FIBRINOGEN FROM BOVINE PLASMA
  • FIBRINOGEN FROM DOG PLASMA
  • FIBRINOGEN FROM MOUSE PLASMA
  • FIBRINOGEN, HUMAN TYPE I FROM HUMAN*PLAS MA
  • FIBRINOGEN TYPE I-S: FROM BOVINE PLASMA
  • fibrinogens
  • Fibrinogen 
  • from Bovine, fraction I
  • FIBRINOGEN
  • FIBRINOGEN, BOVINE
  • FIBRINOGEN(BOVINE),FRACTION I
  • FIBRINOGEN, BOVINE PLASMA
  • FIBRINOGEN, HUMAN
  • Fibrinogen,Bovine95%Clottable
  • Fibrinogen,Human65%Clottable
  • Fibrinogen,Rat60%Clottable
  • Fibrinogen,Horse60%Clottable
  • Fibrinogen,Dog60%Clottable
  • Fibrinogen,Pig60%Clottable
  • Fibrinogen,Bovine75%Clottable
  • factor i
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