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HUMAN FIBRINOGEN

HUMAN FIBRINOGEN
HUMAN FIBRINOGEN structure
CAS No.
9001-32-5
Chemical Name:
HUMAN FIBRINOGEN
Synonyms
C00393;factor i;factor 1;Parenogen;FIBRINOGEN;fibrinogens;Fibrinogen HUMAN FIBRINOGEN;FIBRINOGEN TYPE I;BOVINE FIBRINOGEN
CBNumber:
CB4683502
Molecular Formula:
C6H14O6
Formula Weight:
182.17176
MOL File:
9001-32-5.mol

HUMAN FIBRINOGEN Properties

storage temp. 
-20°C
solubility 
0.9% NaCl: soluble
form 
powder
color 
white
FDA UNII
N94833051K
NCI Dictionary of Cancer Terms
fibrinogen
ATC code
B02BB01
EPA Substance Registry System
Fibrinogens (9001-32-5)
SAFETY
  • Risk and Safety Statements
Hazard Codes  B
WGK Germany  3
10-21
TSCA  Yes

HUMAN FIBRINOGEN price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 341576-M Fibrinogen, Human Plasma Fibrinogen, CAS 9001-32-5, is a soluble plasma glycoprotein that is synthesized in the hepatic parenchymal cells. Contains >90% clottable protein. 9001-32-5 100 mg $72.4 2021-03-22 Buy
Sigma-Aldrich 341573 Fibrinogen, Bovine Plasma Fibrinogen, CAS 9001-32-5, is a soluble plasma glycoprotein that is synthesized in the hepatic parenchymal cells. Contains mpre than 95% clottable protein. 9001-32-5 1 g $191.47 2021-03-22 Buy
Sigma-Aldrich 341573 Fibrinogen, Bovine Plasma 9001-32-5 1gm $199 2020-08-18 Buy
Sigma-Aldrich 341576-M Fibrinogen, Human Plasma Fibrinogen, CAS 9001-32-5, is a soluble plasma glycoprotein that is synthesized in the hepatic parenchymal cells. Contains >90% clottable protein. 9001-32-5 1 g $281.2 2021-03-22 Buy
Sigma-Aldrich 341576-M Fibrinogen, Human Plasma 9001-32-5 1gm-m $304 2020-08-18 Buy

HUMAN FIBRINOGEN Chemical Properties,Uses,Production

Chemical Properties

White or grayish amorphous substance.

Uses

Diagnostic aid (vascular patency); radioactive agent.

Definition

A sterile fraction of normal human blood plasma, dried from the frozen state. In solution, it has the property of being converted into insoluble fibrin when thrombin is added. It is an essential factor in the blood-clotting mechanism.

Purification Methods

A likely impurity is plasminogen. It is purified by glycine precipitation [Mosesson & Sherry Biochemistry 5 2829 1966] to obtain fractions 1-2, then further purified [Blomb.ck & Blomb.ck Arkiv Kemi 10 415 1956] and contaminating plasminogen is removed by passage through a lysine-Sepharose column. Such preparations are at least 95% clottable as determined by Mosesson and Sherry's method (above ref.) in which the OD280 is measured before and after clotting with 5 Units/mL of thrombin (> 3000U/mg). All fibrinogen preparations are treated with calf intestinal alkaline phosphatase to convert any fibrinogen peptide-AP to fibrinogen peptide-A by removing serine-bound phosphate. Solutions are then lyophilised and stored at -20o. [Higgins & Shafer J Biol Chem 256 12013 1981.] It is sparingly soluble in H2O. Aqueous solutions are viscous with isoelectric point at pH 5.5. It is readily denatured by heating above 56o or by chemical agents, e.g. salicylaldehyde, naphthoquinone sulfonates, ninhydrin or alloxan. [Edsall et al. J Am Chem Soc 69 2731 1947, Purification: Cama et al. Naturwissenschaften 48 574 1961, Lorand & Middlebrook Science 118 515 1953, cf. Fuller in Methods Enzymol 163 474 1988.] For plasminogen-deficient fibrinogen from blood plasma, the anticoagulated blood is centrifuged and the plasma is frozen and washed with saline solution. It is treated with charcoal, freeze-thawed and dialysed versus Tris/NaCl buffer. [Maxwell & Nikel Biochemical Preparations 12 16 1968.]

HUMAN FIBRINOGEN Preparation Products And Raw materials

Raw materials

Preparation Products


HUMAN FIBRINOGEN Suppliers

Global( 129)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 29954 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 37282 58
CONIER CHEM AND PHARMA LIMITED
86-18523575427
sales@conier.com CHINA 47498 58
Creative Enzymes
1-631-619-7922
1-631-938-8127 info@creative-enzymes.com United States 8748 58
Hubei Ipure Biology Co., Ltd
+8618062405514
18062427325 ada@ipurechemical.com;ada@ipurechemical.com China 10352 58
HONG KONG IPURE BIOLOGY CO.,LIMITED
18062405514 86 18062405514
ada@ipurechemical.com CHINA 3475 58
Dideu Industries Group Limited
029-88380327
Service@dideu.com CHINA 30014 58
Henan Alfa Chemical Co., Ltd
+8619139973225
adam@alfa-chemical.com;sales4@alfachem.cn China 11868 58
Amadis Chemical Company Limited
0086-571-89925085
0086-571-89925065 sales@amadischem.com China 132148 58

View Lastest Price from HUMAN FIBRINOGEN manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-08-06 HUMAN FIBRINOGEN USP/EP/BP
9001-32-5
US $1.10 / g 1g 99.9% 100 Tons min Dideu Industries Group Limited
2019-07-12 HUMAN FIBRINOGEN
9001-32-5
US $1.00 / KG 1KG 99% 25kg career henan chemical co

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