Lacidipine
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- CAS-Nr.
- 103890-78-4
- Englisch Name:
- Lacidipine
- Synonyma:
- β-GPA;MOTENS;SN-305;LACIREX;LACIPIL;GX-1048;CALDINE;Lacidipin;GR-43659X;LACIDIPINE
- CBNumber:
- CB5296310
- Summenformel:
- C26H33NO6
- Molgewicht:
- 455.54
- MOL-Datei:
- 103890-78-4.mol
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Lacidipine Eigenschaften
- Schmelzpunkt:
- 174-175°C
- Siedepunkt:
- 558.4±50.0 °C(Predicted)
- Dichte
- 1.127±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- Löslichkeit
- DMSO: soluble20mg/mL, clear
- pka
- 3.00±0.70(Predicted)
- Aggregatzustand
- powder
- Farbe
- white to beige
- Merck
- 14,5331
- InChIKey
- GKQPCPXONLDCMU-CCEZHUSRSA-N
- CAS Datenbank
- 103890-78-4(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
Xn |
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| R-Sätze: |
22 |
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| WGK Germany |
3 |
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| RTECS-Nr. |
US7970200 |
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| Toxizität |
mouse,LD50,intraperitoneal,80200ug/kg (80.2mg/kg),SKIN AND APPENDAGES (SKIN): HAIR: OTHERSENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYEBEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY),Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 22, Pg. 335, 1994. |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P501 |
Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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Lacidipine Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Lacidipine is a new second-generation dihydropyridine calcium antagonist introduced
as a once a day treatment for mild to moderate hypertension. It is reported to have high
selectivity for vascular smooth muscle and also a long duration of action. The use of
lacidipine as an antiatherosclerotic agent is currently under investigation.
Chemische Eigenschaften
White-to-Off-White Crystalline Solid
Lacidipine Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Lacidipine Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 353)Lieferanten
103890-78-4()Verwandte Suche:
- 3,5-pyridinedicarboxylicacid,1,4-dihydro-2,6-dimethyl-4-(2-(3-(1,1-dimethylet
- diethylester,(e)-hoxy)-3-oxo-1-propenyl)phenyl)
- MOTENS
- 3,5-Diethyl 4-{2-[(1E)-3-(tert-butoxy)-3-oxoprop-1-en-1-yl]phenyl}-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
- CID 5311217
- Lacidipine，Lacipil
- 4-[2-[(1E)-3-(1,1-dimethylethoxy)-3-oxo-1-propen-1-yl]phenyl]-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid 3,5-diethyl ester
- GX-1048,GR-43659X,SN-305
- LACIPIL
- LACIREX
- LACIDIPINE
- LACIDIPINE-D9
- Lacidipin
- LACIDIPINE, IMPURITY STANDARD BP STANDARD
- LACIDIPINE, BP STANDARD
- LACIDIPINE ASSAY STANDARD BP(CRM STANDARD)
- LACIDIPINE BP STANDARD(CRM STANDARD)
- LACIDIPINE IMPURITY STANDARD BP STANDARD(CRM STANDARD)
- LACIDIPINE IMPURITY STANDARD BP(CRM STANDARD)
- LacidipineC26H33N06
- GX-1048
- GR-43659X
- CALDINE
- (E)-4-[2-[3-(1,1-DIMETHYLETHOXY)-3-OXO-1-PROPENYL]PHENYL]-1,4-DIHYDRO-2,6-DIMETHYL-3,5-PYRIDINEDICARBOXYLIC ACID DIETHYL ESTER
- (E)-4-[2-[3-(1,1-Dimethylethoxy)-3-oxo-1-propenyl]phenyl]-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic Acid Diethyl Ester, GR-43659X, GX-1048, Caldine, Lacipil, Lacirex, Motens
- trans Lacidipine
- Lacidipine (Lacipil, Motens)
- 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-(3-(1,1-dimethylethoxy)-3-oxo-1- propenyl)phenyl)-, diethyl ester, (E)-
- Diethyl 2,6-dimethyl-4-[2-[(E)-3-[(2-methylpropan-2-yl)oxy]-3-oxoprop-1-enyl]phenyl]-1,4-dihydropyridine-3,5-dicarboxylate
- 4-[2-[(1E)-3-(1,1-Dimethylethoxy)-3-oxo-1-propenyl]phenyl]-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid diethyl ester
- 4-[2-[(E)-3-(1,1-Dimethylethoxy)-3-oxo-1-propenyl]phenyl]-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid diethyl ester
- SN-305
- Lacidipine Solution, 100ppm
- Lacidipine Solution, 1000ppm
- LACIPIL;MOTENS
- 2,6-dimethyl-4-[2-[(E)-3-[(2-methylpropan-2-yl)oxy]-3-oxoprop-1-enyl]phenyl]-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester
- 3,5-Pyridinedicarboxylic acid, 4-[2-[(1E)-3-(1,1-dimethylethoxy)-3-oxo-1-propen-1-yl]phenyl]-1,4-dihydro-2,6-dimethyl-, 3,5-diethyl ester
- Lacidipine USP/EP/BP
- (E)-Diethyl 4-(2-(3-(tert-butoxy)-3-oxoprop-1-en-1-yl)phenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
- Lacidipine (GX-1048, GR-43659X, SN-305, Lacipil, Motens)
- LacidipineQ: What is
Lacidipine Q: What is the CAS Number of
Lacidipine Q: What is the storage condition of
Lacidipine Q: What are the applications of
Lacidipine
- β-GPA
- Lacidipine flat
- Lacipil, Motens, Lacidipine
- iethyl2,6-dimethyl-4-[2-[(E)-3-[(2-methylpropan-2-yl)oxy]-3-oxoprop-1-enyl]phenyl]-1,4-dihydropyridine-3,5-dicarboxylate
- Lacidipine
Diethyl 4-{o-[(E)-2-tert-butoxycarbonylethenyl]phenyl}-2,6-
dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
- 103890-78-4
- C26H33NO6
- C26H24NO6D9
- Calcium channel
- Dihydropyridine
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Active Pharmaceutical Ingredients
- Dihydropyridine Class Chemicals
- API
- Lacipil, Motens
