Pramipexole dihydrochloride monohydrate
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- CAS-Nr.
- 191217-81-9
- Englisch Name:
- Pramipexole dihydrochloride monohydrate
- Synonyma:
- Pramipexole dihydrochloride monohydrate;Mirapex;Pramipexole for system suitability CRS;Pra-API;Pramipexole;Unii-3D867np06j;Pramipexole powder;PPX dihydrochloride;Pramipexole HCl hydrate;Pramipexole monohydrate
- CBNumber:
- CB6969615
- Summenformel:
- C10H20ClN3OS
- Molgewicht:
- 265.8
- MOL-Datei:
- 191217-81-9.mol
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Pramipexole dihydrochloride monohydrate Eigenschaften
- Schmelzpunkt:
- 290 °C(dec.)
- storage temp.
- 2-8°C
- Löslichkeit
- Freely soluble in water, soluble in methanol, sparingly soluble or slightly soluble in ethanol (96 per cent), practically insoluble in methylene chloride.
- Farbe
- White to Almost white
- Merck
- 14,7705
- BCS Class
- 1
- InChI
- InChI=1/C10H17N3S.ClH.H2O/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8;;/h7,12H,2-6H2,1H3,(H2,11,13);1H;1H2/t7-;;/s3
- InChIKey
- ZTZQAWQFTIVKMU-DCFBZVEJNA-N
- SMILES
- NC1SC2C[C@@H](NCCC)CCC=2N=1.Cl.O |&1:5,r|
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| WGK Germany |
3 |
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| RTECS-Nr. |
DL3375000 |
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| HS Code |
2934200000 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H336 |
Kann Schläfrigkeit und Benommenheit verursachen. |
Spezifische Zielorgan-Toxizität (einmalige Exposition) |
Kategorie 3 (Schläfrigkeit und Benommenheit) |
Warnung |
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P261, P271, P304+P340, P312,P403+P233, P405, P501 |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P271 |
Nur im Freien oder in gut belüfteten Räumen verwenden. |
| P301+P312 |
BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
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Pramipexole dihydrochloride monohydrate Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Pramipexole dihydrochloride monohydrate is an activator of D2DR, D3DR and D4DR. Pramipexole has been found to have neuroprotective effects independent of its dopamine receptor agonism. It reduces mitochondrial reactive oxygen species (ROS) production and inhibits the activation of apoptotic pathways.
Chemische Eigenschaften
White or almost white, crystalline powder.
Verwenden
Pramipexole is a drug used to treat the symptoms of Parkinson's Disease (PD) and a antidepressant. It is a non-ergot dopamine agonist drug that is efficacious in treating various Parkinson's symptoms such as tremor, rigidity, and bradykinesia (slow movement)
Definition
ChEBI: A hydrate that is the monohydrate of the dihydrochloride salt of pramiprexole.
Allgemeine Beschreibung
Pramipexole Dihydrochloride is a non-ergot dopamine agonist widely used for the treatment of early and advanced Parkinson′s disease (PD). It is also used to treat restless legs syndrome.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Pramipexole dihydrochloride monohydrate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Pramipexole dihydrochloride monohydrate Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 423)Lieferanten
191217-81-9()Verwandte Suche:
- (S)-2-Amino-6-(propylamino)-4,5,6,7-tetrahydrobenzothiazol2HClH2Otetrahydrobenzothiazol
- Mirapex,Sifrol,Mirapexin
- (6S)-N'-Propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine hydrate dihydrochloride
- (S)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole dihydrochloride monohydrate
- Pramipexole
- 2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N6-propyl-, dihydrochloride, monohydrate, (6S)-
- Pramipexole HCl hydrate
- Unii-3D867np06j
- PraMipexole dihydrochloride Monohy
- Pramipexole Dihydrochloride Monohydrate (200 mg)
- 2,6-BenzothiazolediaMine,4,5,6,7-tetrahydro-N6-propyl-,hydrochloride,hydrate(1:2:1),(6S)-
- PraMipexole dihydrochloride Monohyrate
- PraMipexole dihydrochloride hydrate
- (6S)- 4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazolediamine,hydrochloride,hydrate (1:2:1)
- PPX dihydrochloride
- Pramipexole 2HCl Hydrate
- Pramipexole (hydrochloride hydrate)
- Pra-API
- Pramipexole hydrochloride（Dihydrochloride monohydrate）
- Pramipexole dihydrochloride monohydrate CRS
- PramipexoleDihydrochlorideMonohydrate>
- Pramipexole Dihydrochloride Monohyd
- 99.9%, Pramipexole Dihydrochloride Monohydrate?
- Pramipexole Dihydrochloride Monohydrate
DISCONTINUED, offer P700755 or P700750
- Pramipexole dihydrochloride 1-hydrate
- (6S)-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole
-2,6-diamine hydrate dihydrochloride
- Pramipexole monohydrate
- Pramipexole powder
- Pramipexole for system suitability (Y0001187)
- Pramipexole Dihydrochloride MonohydrateQ: What is
Pramipexole Dihydrochloride Monohydrate Q: What is the CAS Number of
Pramipexole Dihydrochloride Monohydrate Q: What is the storage condition of
Pramipexole Dihydrochloride Monohydrate
- Pramipexole Dihydrochloride Monohydrate (1553859)
- Mirapex
- Pramipexole dihydrochloride monohydrate
- Pramipexole for system suitability CRS
- Pramipexole hydrochloride monohydrate
- (S)-N6-Propyl-4,5,6,7-tetrahydrobenzodthiazol-2,6-diamine dihydrochloride hydrate
- 191217-81-9
- 91217-81-9
- C10H17N3S2HClH2O
- C10H17N3S2ClHH2O
- Inhibitors
- Pramipexole
- 191217-81-9
