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ChemicalBook > Produktkatalog >Aktive pharmazeutische Wirkstoffe (APIs) >Flüssigkeits-, Elektrolyt- und Säure-Basen-Haushalt >Säure-Basen-Haushalt regulierende Arzneimittel >Trometamol

Trometamol Produkt Beschreibung

CAS-Nr.77-86-1
Bezeichnung:Trometamol
Englisch Name:Tris Base
Synonyma:
THAM;TRIS;Tham-E;Trizma;riladyl;thamset;TRISMAT;8VTE 1L;Pehanorm;Talatrol
CBNumber:CB8336488
Summenformel:C4H11NO3
Molgewicht:121.14
MOL-Datei:77-86-1.mol
Trometamol physikalisch-chemischer Eigenschaften
Schmelzpunkt:: 167-172 °C(lit.)
Siedepunkt:: 219-220 °C10 mm Hg(lit.)
Dichte: 1,353 g/cm3
Dampfdruck: 0.0267 hPa (20 °C)
Brechungsindex: 1.4170 (estimate)
Flammpunkt:: 219-220°C/10mm
storage temp. : 2-8°C
Löslichkeit: H2O: 4 M at 20 °C, clear, colorless
Aggregatzustand: crystalline
Farbe: white
PH: 10.5-12.0(4 m in water, 25 °C)
pka: 8.1(at 25℃)
Säure-Base-Indikators(pH-Indikatoren): 7 - 9
Wasserlöslichkeit: 550 g/L (25 ºC)
Sensitive : Hygroscopic
maximale Wellenlänge (λmax): λ: 260 nm Amax: 0.10
λ: 280 nm Amax: 0.08
Merck : 14,9772
BRN : 741883
Stabilität:: Stable. Incompatible with bases, strong oxidizing agents. Protect from moisture.
InChIKey: LENZDBCJOHFCAS-UHFFFAOYSA-N
CAS Datenbank: 77-86-1(CAS DataBase Reference)
NIST chemische Informationen: 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-(77-86-1)
EPA chemische Informationen: 1,3-Propanediol, 2-amino-2-(hydroxymethyl)- (77-86-1)
Sicherheit
Kennzeichnung gefährlicher: Xi
R-Sätze:: 36/37/38
S-Sätze:: 26-36-37/39-24/25-23
WGK Germany : 2
RTECS-Nr.: TY2900000
F : 3
TSCA : Yes
HazardClass : IRRITANT
HS Code : 29221980
Giftige Stoffe Daten: 77-86-1(Hazardous Substances Data)
Toxizität: LD50 orally in Rabbit: > 5000 mg/kg LD50 dermal Rat > 5000 mg/kg

Trometamol Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Chemische Eigenschaften
White, crystalline solid. PH (0.1M aqueous solution) 10.6, corrosive to copper, brass, aluminum. Solubility in water 80 g/100 cc (20C). Combustible.
Verwenden
tromethamine can help mask odor in a formulation. It is also used as a buffer, keeping product pH stable.
Verwenden
In the synthesis of surface-active agents, vulcanization accelerators, pharmaceuticals. As emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, leather dressings, textile specialties, polishes, cleaning Compounds, so-called soluble oils. Absorbent for acidic gases. Biological buffer.
Trademarks
Tham (Hospira).
Biologische Aktivität
Commonly used laboratory reagent
läuterung methode
TRIS can ordinarily be obtained in highly pure form suitable for use as an acidimetric standard. If only impure material is available, it should be crystallised from 20% EtOH, aqueous MeOH (m 171.1o) or isopropanol (m 172-173o). Dry it in a vacuum desiccator over P2O5 or CaCl2. Alternatively, it is dissolved in twice its weight of water at 55-60o, filtered, concentrated to half its volume and poured slowly, with stirring, into about twice its volume of EtOH. The crystals which separate on cooling to 3-4o are filtered off, washed with a little MeOH, air dried by suction, then finally ground and dried in a vacuum desiccator over P2O5. It has also been recrystallised from water, MeOH or aqueous MeOH, and vacuum dried at 80o for 2 days. [Beilstein 4 H 303, 4 III 857, 4 IV 1903.]
Trometamol Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Nitromethan Kaliumcarbonat Palladium Methanol 2-(Hydroxymethyl)-2-nitro-1,3-propandiol
Downstream Produkte
Trometamol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.      Global( 465)Lieferanten     
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
Yunbio Tech Co.,Ltd.
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Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
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Chemwill Asia Co.,Ltd.
86-21-51086038
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Capot Chemical Co.,Ltd.
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Henan DaKen Chemical CO.,LTD.
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Shanghai Bojing Chemical Co.,Ltd.
+86-21-37122233
+86-21-37127788Candy@bj-chem.com CHINA 495 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
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Shanghai Time Chemicals CO., Ltd.
+86-021-57951555
+86-021-57951555jack.li@time-chemicals.com CHINA 1367 55
Mainchem Co., Ltd.
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Zjartschem
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+86-571-87063838jocelynpan@zjarts.com CHINA 998 58
 
77-86-1(Trometamol)Verwandte Suche:
N,N-Dimethyl-phenylendiamin (p) ALTRENOGEST Lithiumbis(trimethylsilyl)amid 4,4'-Diamino-diphenyl-methan 2-(Hydroxymethyl)-2-nitro-1,3-propandiol Trometamol N-(Tri(hydroxymethyl)methyl)glycin Betain Glycin 2-METHYL-1,3-PROPANEDIOL Ethylidintrimethanol Propan-1,3-diol methylol cellulose 2-[Bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)propan-1,3-diol 2-Hydroxyethylmethacrylat 3-Aminopropan-1,2-diol BUFFER SOLUTION PH = 6,00 (20 °C) (POTASSIUM DIHYDROGEN PHOSPHATE/SODIUM HYDROXIDE) Hydroxymethyl
2-amino-2-(hydroxymethyl)-3-propanediol 2-Amino-2-hydroxymethylpropanediol 2-Amino-2-methylol-1,3-propanediol 3-Propanediol,2-amino-2-(hydroxymethyl)-1 Addex-Tham Amino-2-(hydroxymethyl)-1,3-propanediol Aminotrimethylolmethane Aminotris(hydroxymethyl)methane Apiroserum Tham Methanamine, 1,1,1-tris(hydroxymethyl)- Methylamine, 1,1,1-tris(hydroxymethyl)- minotri(hydroxymethyl)methane Pehanorm rigmo base riladyl 1,1,1-tris(hydroxymethyl)-methanamin 1,1,1-tris(hydroxymethyl)-methylamin 1,1,1-tris(hydroxymethyl)methylamine 1,3-Propanediol,2-amino-2-(hydroxymethyl)- Tris(hydroxymethyl)amino-methan tris(hydroxymethyl)aminomethane(tris) Tris(hydroxymethyl)methanamine Tris, free base tris[bufferingagent] Trisamin trisaminebuffer Trisaminol tris-hydroxymethyl-aminomethan Talatrol Tham-E thamset Tris amino molecular biology grade Tris amino ultra pure standard Tris buffertris-hydroxymethyl-aminomethan tris(bufferingagent) Trispuffer Tris-steril Trizma Trometamole Tromethamin Tromethamine (CTFA) Tromethanmin Tutofusin tris TRIS[HYDROXYMETHYL] AMINOETHANE TRIS BASE TRIS BUFFER TRIS BUFFER PH 7.5 TRIS BUFFER PH 8.0 TRIS BUFFER PH 8.8 TRIS BUFFER SUBSTANCE TRISAMINE TRIS AMINO TRIMETHYLOL AMINOMETHANE TROMETHANE TROMETHANOL TRIZMA BASE TRIZMA BUFFER TRIZMA(R) PRE-SET TYPE 7.2-FT
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