Butenafine hydrochloride

Butenafine hydrochloride Struktur
101827-46-7
CAS-Nr.
101827-46-7
Englisch Name:
Butenafine hydrochloride
Synonyma:
BUTENAFINE HCL;kp-363;MentaX;Volley;Scorba;Meridam;Butenafine HCI;Butenafine Hydro;Butenafine hydrochL;Butenafine hydrochlo
CBNumber:
CB8256177
Summenformel:
C23H27N.ClH
Molgewicht:
353.93
MOL-Datei:
101827-46-7.mol

Butenafine hydrochloride Eigenschaften

Schmelzpunkt:
210-214°C
storage temp. 
room temp
Löslichkeit
DMSO: ≥10mg/mL
Aggregatzustand
powder
Farbe
white to off-white
Merck 
14,1518
InChI
InChI=1S/C23H27N.ClH/c1-23(2,3)21-14-12-18(13-15-21)16-24(4)17-20-10-7-9-19-8-5-6-11-22(19)20;/h5-15H,16-17H2,1-4H3;1H
InChIKey
LJBSAUIFGPSHCN-UHFFFAOYSA-N
SMILES
C12C=CC=CC=1C=CC=C2CN(C)CC1=CC=C(C(C)(C)C)C=C1.Cl
CAS Datenbank
101827-46-7(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Kennzeichnung gefährlicher Xn
R-Sätze: 21
S-Sätze: 44
WGK Germany  nwg
RTECS-Nr. QJ8585000
HS Code  29214990
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H312 Gesundheitsschädlich bei Hautkontakt. Akute Toxizität dermal Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P280,P302+P352, P312, P322, P363,P501
Sicherheit
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.

Butenafine hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Butenafine hydrochloride is a new benzylamine antifungal which appears to block the squalene epoxidation step of sterol synthesis in fungi. Active against a broad spectrum of fungi, butenafine hydrochloride is more effective in a guinea-pig model of tinea pedis than clotrimazole, naftifine and tolnaftate. Its efficacy is partially attributed to its long retention time in the skin.

Chemische Eigenschaften

White Solid

Verwenden

Butenafine hydrochloride has been used as a standard in high-performance liquid chromatography (HPLC) method to determine butenafine hydrochloride in butenafine-loaded nanosponges.

Definition

ChEBI: The hydrochloride salt of butenafine. An inhibitor of squalene epoxidase, an enzyme responsible for the creation of sterols needed in fungal cell membranes, it is used for treatment of dermatological fungal infections.

Allgemeine Beschreibung

Butenafine hydrochloride is chemically known as N-4-tertbutylbenzyl-N-methyl-1-naphthalenemethylamine hydrochloride. Butenafine, a benzylamine derivative, is a new generation antimycotic compound. It is easily soluble in methanol, ethanol, dichloromethane, and chloroform, but not in water. The allyl radical in butenafine hydrochloride is substituted by a butylbenzyl group.

Nebenwirkungen

Side Effects:
Blistering, burning, crusting, dryness, or flaking of the skin where the medicine is applied. itching, scaling, severe redness, soreness, or swelling of the skin where the medicine is applied.

Butenafine hydrochloride Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Butenafine hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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101827-46-7()Verwandte Suche:


  • kp-363
  • n-((4-(1,1-dimethylethyl)phenyl)methyl)-n-methyl-1-naphthalenemethanaminehyd
  • n-((4-(1,1-dimethylethyl)phenyl)methyl)-n-methyl-1-naphthalenemethanaminhy
  • n-(4-tert-butylbenzyl)-n-methyl-1-naphthalenemethylamine hydrochloride
  • BUTENAFINE HYDROCHLORIDE
  • Butenafine hydrochloide
  • N-(4-t-Butylbenzyl)-N-Methyl-1-naphthalenemethylamine hydrochloride
  • 4-tert-Butylbenzylmethyl 1-naphtylmethylamine·hydrochloride
  • Meridam
  • Volley
  • MentaX
  • N-[[4-(1,1-Dimethylethyl)phenyl]methyl]-N-methyl-1-naphthalenemethanamine hydrochloride
  • Scorba
  • Butenafine hydrochlo
  • (4-tert-butylphenyl)-N-methyl-N-(naphthalen-1-ylmethyl)methanamine hydrochloride
  • N-(p-tert-butylbenzyl)-N-methyl-1-naphthalenemethylamine hydrochloride
  • N-(4-(tert-Butyl)benzyl)-N-methyl-1-(naphthalen-1-yl)methanamine hydrochloride
  • 1-(4-tert-butylphenyl)-N-methyl-N-(1-naphthalenylmethyl)methanamine hydrochloride
  • Butenafine Hydro
  • Butenafine Hydrochloride >
  • KP363 (Hydrochloride)
  • Butenafine hydrochL
  • Butenafine hydrochloride USP/EP/BP
  • Butenafin hydrochloride
  • naphthalenemethanaminehyd
  • Top Quality Butenafine Hydrochloride Powder Price CAS?101827-46-7
  • Quality Butenafine Hydrochloride 101827-46-7 Butenafine with Fast&Safe Delivery
  • Butenafine HydrochlorideQ: What is Butenafine Hydrochloride Q: What is the CAS Number of Butenafine Hydrochloride Q: What is the storage condition of Butenafine Hydrochloride Q: What are the applications of Butenafine Hydrochloride
  • TIANFUCHEM--101827-46-7--Butenafine hydrochloride in stock
  • BUTENAFINE HCL
  • Butanoicacid,4-[[(1,7-dimethylethoxy)carbonyl]methylamino]-
  • Butenafine HCI
  • Butenafine Hydrochloride, ≥ 98.0%
  • 101827-46-7
  • 101827-46-1
  • 101827-47-7
  • C23H27NHCl
  • C23H28NCl
  • C23H28ClN
  • C23H27NHClC23H28ClN
  • C23H27NClH
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  • Biochemistry
  • Butenafine
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