Carbetocin

Carbetocin Struktur
37025-55-1
CAS-Nr.
37025-55-1
Bezeichnung:
Carbetocin
Englisch Name:
Carbetocin
Synonyma:
Carbetocin Acetate;Pabal;DeaMino-2-O-Methyltyrosine-1-carbaoxytocin;d(COMOT);Depotocin;Carbansin;Duratocin;Lonactene;CARBETOCIN;Carbetoxin
CBNumber:
CB9175745
Summenformel:
C45H69N11O12S
Molgewicht:
988.17
MOL-Datei:
37025-55-1.mol

Carbetocin Eigenschaften

Schmelzpunkt:
140 - 160°C
Siedepunkt:
1477.9±65.0 °C(Predicted)
alpha 
D -69.0° (c = 0.25 in 1M acetic acid)
Dichte
1.218±0.06 g/cm3(Predicted)
storage temp. 
-15°C
Löslichkeit
DMSO (Slightly), Methanol (Slightly)
Aggregatzustand
powder
pka
13.07±0.70(Predicted)
Farbe
white to beige
Wasserlöslichkeit
Soluble to 29.65 mg/ml in water
Stabilität:
Hygroscopic
InChIKey
NSTRIRCPWQHTIA-FOILTOEQNA-N

Sicherheit

WGK Germany  3

Carbetocin Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Carbetocin is an obstetric drug used to control postpartum hemorrhaging.
A new synthetic analog of oxytocin, carbetocin, is long acting and also has a rapid onset of action. It is an oxytocin receptor agonist and also stimulates milk let down due to its action on oxytocin receptors of myoepithelial cells.

Definition

ChEBI: Oxytocin in which the hydrogen on the phenolic hydroxy group is substituted by methyl, the amino group on the cysteine residue is substituted by hydrogen, and the sulfur of the cysteine residue is replaced by a methylene group. A synthetic carba-analogue o oxytocin, it is used to control bleeding after giving birth. Like oxytocin, it causes contraction of the uterus.

Biochem/physiol Actions

Carbetocin is a potent agonist of the oxytocin receptor, with improved in vivo stability over oxytocin.

Nebenwirkungen

One of the most commonly reported side effects of Carbetocin is hypotension, or low blood pressure. Another frequently observed side effect is nausea, often accompanied by vomiting. It can also cause headache.

Carbetocin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Carbetocin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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37025-55-1(Carbetocin)Verwandte Suche:


  • Butyryl-Tyr(Me)-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2(Disulfide bond)
  • N-(4-Mercapto-1-oxobutyl)-O-methyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-leucyl-glycinamidecyclic (1-5)-thioether acetate
  • CARBAOXYTOCIN
  • Carbetocin, (Butyryl1,Tyr(Me)2)-1-Carbaoxytocin
  • BUTYRYL-TYR(ME)-ILE-GLN-ASN-CYS-PRO-LEU-GLY-NH2, (SULFIDE BOND BETWEEN BUTYRYL-4-YL AND CYS)
  • BUTYRYL-TYR(ME)-ILE-GLN-ASN-CYS-PRO-LEU-GLY-NH2 TRIFLUOROACETATE SALT
  • (BUTYRYL1,TYR(ME)2)-1-CARBAOXYTOCIN TRIFLUOROACETATE SALT
  • (BUTYRYL1,TYR(ME)2)-OXYTOCIN
  • (BUTYRYL1,TYR(ME)2)-OXYTOCIN TRIFLUOROACETATE SALT
  • CARBETOCIN
  • CARBETOCIN TRIFLUOROACETATE SALT
  • (2-O-METHYLTYROSINE)-DE-AMINO-1-CARBAOXYTOCIN
  • M.W. 988.17 C45H69N11O12S
  • 1-Butanoic acid-2-(O-methyl-L-tyrosine)-1-carbaoxytocin
  • 2-Deamino-L-Abu(1)-O-methyl-L-Tyr-L-Ile-L-Gln-L-Asn-L-Cys(1)-L-Pro-L-Leu-Gly-NH2
  • Depotocin
  • (Butyryl1,Tyr(Me)2)-1-Carbaoxytocin, (Butyryl1,Tyr(Me)2)-Oxytocin
  • Butyryl-Tyr(Me)-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2
  • 1-CARBAOXYTOCIN, 1-BUTANOIC ACID-2-(O-METHYL-L-TYROSINE)-
  • Carbansin
  • Carbetocinum
  • Carbetocin Acetate, Carbetocino, Carbetocinum
  • Glycinamide, N-(4-mercapto-1-oxobutyl)-O-methyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-leucyl-, cyclic (1→5)-thioether
  • CARBETOCIN USP/EP/BP
  • CarbetocinQ: What is Carbetocin Q: What is the CAS Number of Carbetocin Q: What is the storage condition of Carbetocin Q: What are the applications of Carbetocin
  • High purity CAS 37025-55-1 CARBETOCIN
  • Carbetocino
  • Carbaoxytocin acetate salt
  • 37025-55-1(Carbetocin acetate)
  • Duratocin
  • DURATOCIN;PABAL;LONACTENE;37025-55-1(CARBETOCIN ACETATE);
  • Lonactene
  • Carbetoxin
  • Carbetocin Acetate
  • DeaMino-2-O-Methyltyrosine-1-carbaoxytocin
  • d(COMOT)
  • Pabal
  • 1-Carbaoxytocin,1-butanoic acid-2-(O-methyl-L-tyrosine)- (9CI)
  • Cabexin oxytocin
  • 37025-55-1
  • C45H69N11O12s
  • Other APIs
  • Peptide
  • Vasopressin and Oxytocin receptor
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
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