ChemicalBook >> CAS DataBase List >>Carbetocin

Carbetocin

CAS No.
37025-55-1
Chemical Name:
Carbetocin
Synonyms
Carbetocin Acetate;Pabal;DeaMino-2-O-Methyltyrosine-1-carbaoxytocin;d(COMOT);Depotocin;Carbansin;Duratocin;Lonactene;CARBETOCIN;Carbetoxin
CBNumber:
CB9175745
Molecular Formula:
C45H69N11O12S
Molecular Weight:
988.17
MDL Number:
MFCD01076600
MOL File:
37025-55-1.mol
Last updated:2024-04-17 18:50:11

Carbetocin Properties

Melting point 140 - 160°C
Boiling point 1477.9±65.0 °C(Predicted)
alpha D -69.0° (c = 0.25 in 1M acetic acid)
Density 1.218±0.06 g/cm3(Predicted)
storage temp. -15°C
solubility DMSO (Slightly), Methanol (Slightly)
form powder
pka 13.07±0.70(Predicted)
color white to beige
Water Solubility Soluble to 29.65 mg/ml in water
Stability Hygroscopic
InChIKey NSTRIRCPWQHTIA-FOILTOEQNA-N
FDA UNII 88TWF8015Y
NCI Drug Dictionary carbetocin
ATC code H01BB03

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Danger
Hazard statements  H312+H332
WGK Germany  3

Carbetocin price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML0748 Carbetocin acetate ≥93% (HPLC) 37025-55-1 5mg $108 2024-03-01 Buy
Sigma-Aldrich SML0748 Carbetocin acetate ≥93% (HPLC) 37025-55-1 25mg $425 2024-03-01 Buy
Tocris 4852 Carbetocin 37025-55-1 10 $173 2021-12-16 Buy
Usbiological 506367 Carbetocin 37025-55-1 5mg $296 2021-12-16 Buy
TRC C175925 Carbetocin 37025-55-1 50mg $375 2021-12-16 Buy
Product number Packaging Price Buy
SML0748 5mg $108 Buy
SML0748 25mg $425 Buy
4852 10 $173 Buy
506367 5mg $296 Buy
C175925 50mg $375 Buy

Carbetocin Chemical Properties,Uses,Production

Description

Carbetocin is an alternative synthetic oxytocin-receptor agonist available in Canada, the United Kingdom, and other countries,but not the United States. A large multinational randomized noninferiority trial (N=29,645) found that carbetocin was noninferior to oxytocin for prevention of postpartum hemorrhage and need for additional uterotonic agents after vaginal delivery. Carbetocin has a longer duration of action than oxytocin, eliminating the need for prolonged infusion.

Uses

Carbetocin is an obstetric drug used to control postpartum hemorrhaging.
A new synthetic analog of oxytocin, carbetocin, is long acting and also has a rapid onset of action. It is an oxytocin receptor agonist and also stimulates milk let down due to its action on oxytocin receptors of myoepithelial cells.

Definition

ChEBI: Oxytocin in which the hydrogen on the phenolic hydroxy group is substituted by methyl, the amino group on the cysteine residue is substituted by hydrogen, and the sulfur of the cysteine residue is replaced by a methylene group. A synthetic carba-analogue o oxytocin, it is used to control bleeding after giving birth. Like oxytocin, it causes contraction of the uterus.

Biochem/physiol Actions

Carbetocin is a potent agonist of the oxytocin receptor, with improved in vivo stability over oxytocin.

storage

Store at -20°C

Carbetocin Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 296)Suppliers
Supplier Tel Email Country ProdList Advantage
AFINE CHEMICALS LIMITED
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Hubei Harvest Chemical CO.,Ltd
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Nantong Guangyuan Chemicl Co,Ltd
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hebei hongtan Biotechnology Co., Ltd
+86-86-1913198-3935 +8617331935328 sales03@chemcn.cn China 951 58
Shaanxi TNJONE Pharmaceutical Co., Ltd
+8618740459177 sarah@tnjone.com China 893 58
Alpha Biopharmaceuticals Co., Ltd
+86-411-39042497 +8613921981412 sales@alphabiopharm.com China 886 58

View Lastest Price from Carbetocin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Carbetocin pictures 2024-04-26 Carbetocin
37025-55-1
US $30.00 / box 1box 98% 2000kg hebei hongtan Biotechnology Co., Ltd
Carbetocin Acetate pictures 2024-04-18 Carbetocin Acetate
37025-55-1
US $0.00 / g 50g 99% 100kg Shaanxi TNJONE Pharmaceutical Co., Ltd
Carbetocin Acetate pictures 2024-04-15 Carbetocin Acetate
37025-55-1
US $1.00 / mg 100mg 98.0% 5ton/month ANHUI SHENGZHIKAI BIOTECHNOLOGY CO.,LTD
  • Carbetocin pictures
  • Carbetocin
    37025-55-1
  • US $30.00 / box
  • 98%
  • hebei hongtan Biotechnology Co., Ltd

Carbetocin Spectrum

Butyryl-Tyr(Me)-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2(Disulfide bond) N-(4-Mercapto-1-oxobutyl)-O-methyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-leucyl-glycinamidecyclic (1-5)-thioether acetate CARBAOXYTOCIN Carbetocin, (Butyryl1,Tyr(Me)2)-1-Carbaoxytocin BUTYRYL-TYR(ME)-ILE-GLN-ASN-CYS-PRO-LEU-GLY-NH2, (SULFIDE BOND BETWEEN BUTYRYL-4-YL AND CYS) BUTYRYL-TYR(ME)-ILE-GLN-ASN-CYS-PRO-LEU-GLY-NH2 TRIFLUOROACETATE SALT (BUTYRYL1,TYR(ME)2)-1-CARBAOXYTOCIN TRIFLUOROACETATE SALT (BUTYRYL1,TYR(ME)2)-OXYTOCIN (BUTYRYL1,TYR(ME)2)-OXYTOCIN TRIFLUOROACETATE SALT CARBETOCIN CARBETOCIN TRIFLUOROACETATE SALT (2-O-METHYLTYROSINE)-DE-AMINO-1-CARBAOXYTOCIN M.W. 988.17 C45H69N11O12S 1-Butanoic acid-2-(O-methyl-L-tyrosine)-1-carbaoxytocin 2-Deamino-L-Abu(1)-O-methyl-L-Tyr-L-Ile-L-Gln-L-Asn-L-Cys(1)-L-Pro-L-Leu-Gly-NH2 Depotocin (Butyryl1,Tyr(Me)2)-1-Carbaoxytocin, (Butyryl1,Tyr(Me)2)-Oxytocin Butyryl-Tyr(Me)-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 1-CARBAOXYTOCIN, 1-BUTANOIC ACID-2-(O-METHYL-L-TYROSINE)- Carbansin Carbetocinum Carbetocin Acetate, Carbetocino, Carbetocinum Glycinamide, N-(4-mercapto-1-oxobutyl)-O-methyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-leucyl-, cyclic (1→5)-thioether CARBETOCIN USP/EP/BP CarbetocinQ: What is Carbetocin Q: What is the CAS Number of Carbetocin Q: What is the storage condition of Carbetocin Q: What are the applications of Carbetocin High purity CAS 37025-55-1 CARBETOCIN Carbetocino Carbaoxytocin acetate salt 37025-55-1(Carbetocin acetate) Duratocin DURATOCIN;PABAL;LONACTENE;37025-55-1(CARBETOCIN ACETATE); Lonactene Carbetoxin Carbetocin Acetate DeaMino-2-O-Methyltyrosine-1-carbaoxytocin d(COMOT) Pabal 1-Carbaoxytocin,1-butanoic acid-2-(O-methyl-L-tyrosine)- (9CI) 37025-55-1 C45H69N11O12s Other APIs Peptide Vasopressin and Oxytocin receptor Intermediates & Fine Chemicals Pharmaceuticals