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Florfenicol Produkt Beschreibung

Florfenicol Struktur
73231-34-2
CAS-Nr.
73231-34-2
Englisch Name:
Florfenicol
Synonyma:
NUFLOR;AQUAFEN;Aquaflor;SCH-25298;FLUPROFEN;lorfenicol;Florfeniol;FLORFENICOL;FLORFENICOL HCL;Florfenicol ,99%
CBNumber:
CB9195978
Summenformel:
C12H14Cl2FNO4S
Molgewicht:
358.21
MOL-Datei:
73231-34-2.mol

Florfenicol Eigenschaften

Schmelzpunkt:
153 °C
Siedepunkt:
618℃
alpha 
26 +17.9° (DMF)
RTECS-Nr.
DB6034000
Flammpunkt:
>110°(230°F)
storage temp. 
0-6°C
Löslichkeit
Soluble in ethanol to 25mM and in DMSO to 100mM
Aggregatzustand
solid
Merck 
14,4109
CAS Datenbank
73231-34-2(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher Xi
R-Sätze: 36/37/38
S-Sätze: 26-36
WGK Germany  3
HS Code  29419090

Florfenicol Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-Sätze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

Chemische Eigenschaften

White Crystalline Powder

Verwenden

Fluorinated derivative of thiamphenicol. Inhibits bacterial protein synthesis by binding to ribosome 50S and 70S subunits. An antibacterial

Verwenden

Antibacterial;Protein synthesis inhibitor

Verwenden

Florfenicol is a fluorinated derivative of thiamphenicol. Florfenicol inhibits bacterial protein synthesis by binding to ribosome 50S and 70S subunits. Florfenicol is used as an antibacterial.

Verwenden

Florfenicol is synthesised from thiamphenicol by replacing the 3-hydroxy group with fluorine, first synthesised at Schering in 1980. By replacing the hydroxy group, it was rationalised that chloramphenicol resistance via chloramphenicol acetyltransferase could be eliminated. Florfenicol is a broad spectrum antibiotic with good activity against Gram negative and anaerobic bacteria. Florfenicol acts by binding to the 23S sub-unit of the 50S ribosome, inhibiting protein synthesis. Florfenicol has been extensively studied with over 400 literature citations.

Definition

ChEBI: A carboxamide that is the N-dichloroacetyl derivative of (1R,2S)-2-amino-3-fluoro-1-[4-(methanesulfonyl)phenyl]propan-1-ol. A synthetic veterinary antibiotic that is used for treatment of bovine respirat ry disease and foot rot; also used in aquaculture.

Veterinary Drugs and Treatments

The drug is approved for use in cattle only (in the USA) for the treatment of bovine respiratory disease (BRD) associated with Pasteurella haemolytica, Pasteurella multocida, and Haemophilus somnus.
Because florfenicol has activity against a wide range of microorganisms (e.g., Mycoplasma), it may be useful for treating other infections in cattle (or other species) as well, but specific data is limited.

Florfenicol Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Florfenicol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 288)Lieferanten
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 sales@capotchem.com China 19918 60
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3194 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21745 58
Shanghai Bojing Chemical Co.,Ltd.
+86-21-37122233
+86-21-37127788 Candy@bj-chem.com CHINA 493 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20672 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32447 55
Hubei XinRunde Chemical Co., Ltd.
+8615102730682; +8618874586545
02783214688 bruce@xrdchem.cn CHINA 535 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 1852 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 27142 58

73231-34-2()Verwandte Suche:


  • Acetamide, 2,2-dichloro-N-(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-4-(methylsulfonyl)phenylethyl-
  • 2,2-Dichloro-N-[(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide
  • Aquaflor
  • Aquafen, Nuflor, SCH-25298, [R-(R*,S*)]-2,2-Dichloro-N-[1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide
  • 2,2-Dichloro-N-(1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)ethyl)acetamide
  • 2,2-Dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamid
  • Benzenesulfonic acid, 4-(2-((dichloroacetyl)amino)-3-fluoro-1-hydroxypropyl)-, methyl ester, (R-(R*,S*))
  • [(R-(R*,S*)]-4-[2-[(Dichloroacetyl)amino]-3-fluoro-1-hydroxypropyl]benzensulfonic acid methyl ester
  • Florfenicol ,99%
  • 2,2-Dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)-2-propyl]acetamide D-(-)-threo-2-Dichloroacetamido-3-fluoro-1-(4-methylsulfonylphenyl)-1-propanol
  • (-)Florfenicol, Sch 25298
  • lorfenicol
  • FLORFENICOL HCL
  • 10% water-soluble Florfenicol
  • 30% water-soluble Florfenicol
  • 40% water-soluble Florfenicol
  • 70% water-soluble Florfenicol
  • (r-(r*,s*))-methyleste
  • 2,2-dichloro-n-(1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)ethyl
  • 4-(2-((dichloroacetyl)amino)-3-fluoro-1-hydroxypropyl)-benzenesulfonicaci
  • FLORFENICOL
  • AQUAFEN
  • 2,2-dichloro-n-[(1r,2s)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide
  • NUFLOR
  • [r-(r*, r*)]-n-[1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulforyl)phenyl)-ethyl]-2,2-dichloroacetamide
  • [R-(R*,S*)]-2,2-DICHLORO-N-[1-(FLUOROMETHYL)-2-HYDROXY-2-[4-(METHYLSULFONYL)PHENYL]ETHYL]ACETAMIDE
  • SCH-25298
  • Florfeniol
  • FLUPROFEN
  • Fluorothiamphenicol
  • Sch-25298, Aquafen
  • Florfenicol solution,1000ppm
  • 2,2-dichloroacetamide 2,2-Dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide [R-(R*,S*)]-2,2-Dichloro-N-[1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide Aquafen Nuflor
  • Florfenicol, 98%, veterinary antibiotic
  • Florfenicol in stock GMP Factory
  • 73231-34-2
  • 7323-34-2
  • C12H14Cl2FNO4S
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