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rhapontigenin

rhapontigenin Structure
rhapontigenin structure
CAS No.
500-65-2
Chemical Name:
rhapontigenin
Synonyms
Protigenin;rhapontigenin;3-benzenediol;Rhapontigenin >rhapontigenin USP/EP/BP;-5-(3-Hydroxy-4-methoxystyryl);COc2ccc(/C=C/c1cc(O)cc(O)c1)cc2O;(E)-4'-Methoxy-3,3',5-stilbenetriol;3,3',5-Trihydroxy-4'-methoxy-trans-stilbene;5-[(1E)-2-(3-hydroxy-4-methoxyphenyl)ethenyl]-1
CBNumber:
CB01309681
Molecular Formula:
C15H14O4
Molecular Weight:
258.27
MDL Number:
MFCD00017718
MOL File:
500-65-2.mol
MSDS File:
SDS
Last updated:2023-06-08 17:06:34
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rhapontigenin Properties

Melting point 189.0 to 193.0 °C
Boiling point 503.6±38.0 °C(Predicted)
Density 1.345±0.06 g/cm3(Predicted)
storage temp. 4°C, protect from light
solubility ≤30mg/ml in ethanol;30mg/ml in DMSO;30mg/ml in dimethyl formamide
form powder to crystal
pka 9.17±0.10(Predicted)
color White to Light yellow
CAS DataBase Reference 500-65-2
FDA UNII 22BG4NNH6W

SAFETY

Risk and Safety Statements

HS Code  2914.50.3000

rhapontigenin price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical R0089 Rhapontigenin >98.0%(GC) 500-65-2 100mg $310 2024-03-01 Buy
Cayman Chemical 13293 Rhapontigenin ≥98% 500-65-2 1mg $89 2024-03-01 Buy
Cayman Chemical 13293 Rhapontigenin ≥98% 500-65-2 5mg $395 2024-03-01 Buy
Cayman Chemical 13293 Rhapontigenin ≥98% 500-65-2 10mg $700 2024-03-01 Buy
Cayman Chemical 13293 Rhapontigenin ≥98% 500-65-2 25mg $1528 2024-03-01 Buy
Product number Packaging Price Buy
R0089 100mg $310 Buy
13293 1mg $89 Buy
13293 5mg $395 Buy
13293 10mg $700 Buy
13293 25mg $1528 Buy

rhapontigenin Chemical Properties,Uses,Production

Description

Rhapontigenin is a natural analog of resveratrol and an inhibitor of CYP1A1.

Description

Rhapontigenin is a natural analog of resveratrol with antioxidant and anti-cancer activity. It is a mechanism-based, selective inactivator of cytochrome P450 1A1 (IC50 = 400 nM), an aryl hydrocarbon hydroxylase which activates polycyclic aromatic hydrocarbons that act as procarcinogens. At higher concentrations, rhapontigenin inhibits the proliferation of HepG2 and HL-60R cancer cell lines (IC50 = 48 μM).

Uses

Rhapontigenin is a natural analog of resveratrol and an inhibitor of CYP1A1.

Uses

Rhapontigenin is a natural analog of resveratrol with antioxidant and anti-cancer activity. It is a mechanism-based, selective inactivator of cytochrome P450 1A1 (IC50 = 400 nM), an aryl hydrocarbon hydroxylase which activates polycyclic aromatic hydrocarbons that act as procarcinogens. At higher concentrations, rhapontigenin inhibits the proliferation of HepG2 and HL-60R cancer cell lines (IC50 = 48 μM).[Cayman Chemical]

Definition

ChEBI: Rhapontigenin is a stilbenoid.

References

[1]. chun yj, ryu sy, jeong tc, et al. mechanism-based inhibition of human cytochrome p450 1a1 by rhapontigenin. drug metab dispos. 2001 apr;29(4 pt 1):389-93.
[2]. roberti m1, pizzirani d, simoni d, et al. synthesis and biological evaluation of resveratrol and analogues as apoptosis-inducing agents. j med chem. 2003 jul 31;46(16):3546-54.
[3]. roupe ka1, helms gl, halls sc, et al. preparative enzymatic synthesis and hplc analysis of rhapontigenin: applications to metabolism, pharmacokinetics and anti-cancer studies. j pharm pharm sci. 2005 aug 22;8(3):374-86.

rhapontigenin Preparation Products And Raw materials

Raw materials

Preparation Products

rhapontigenin Suppliers

Global( 157)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Zheyan Biotech Co., Ltd. 		18017610038 zheyansh@163.com CHINA 3620 58
Chengdu Greenpure Biopharma CO.,Ltd 		18283602253 jancyzheng@gcgreenpure.com China 952 58
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Zhejiang ZETian Fine Chemicals Co. LTD 		18957127338 stella@zetchem.com China 2141 58
Chengdu GLP biotechnology Co Ltd 		028-87075086 13350802083 scglp@glp-china.com CHINA 1824 58
Chengdu Biopurify Phytochemicals Ltd. 		+8618080483897 sales@biopurify.com China 3424 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28180 58
Chongqing Chemdad Co., Ltd 		+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Shanghai Standard Technology Co., Ltd. 		18502101150 ft-sales@nature-standard.com CHINA 1923 58
Neostar United (Changzhou) Industrial Co., Ltd. 		+86-519-519-85557386 marketing1@neostarunited.com China 8349 58
Supplier Advantage
Shanghai Zheyan Biotech Co., Ltd. 		58
Chengdu Greenpure Biopharma CO.,Ltd 		58
career henan chemical co 		58
Zhejiang ZETian Fine Chemicals Co. LTD 		58
Chengdu GLP biotechnology Co Ltd 		58
Chengdu Biopurify Phytochemicals Ltd. 		58
Hubei Jusheng Technology Co.,Ltd. 		58
Chongqing Chemdad Co., Ltd 		58
Shanghai Standard Technology Co., Ltd. 		58
Neostar United (Changzhou) Industrial Co., Ltd. 		58

View Lastest Price from rhapontigenin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Rhapontigenin pictures 2024-03-28 Rhapontigenin
500-65-2
 US $0.00 / kg 25kg 98% Inquiry PNP Biotech Co. Ltd
Rhapontigenin pictures 2023-02-24 Rhapontigenin
500-65-2
 US $0.00 / mg 5mg ≥98%(HPLC) 10 g Shanghai Standard Technology Co., Ltd.
Rhapontigenin pictures 2021-07-02 Rhapontigenin
500-65-2
 US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
  • Rhapontigenin pictures
  • Rhapontigenin
    500-65-2
  • US $0.00 / mg
  • ≥98%(HPLC)
  • Shanghai Standard Technology Co., Ltd.
  • Rhapontigenin pictures
  • Rhapontigenin
    500-65-2
  • US $15.00-10.00 / KG
  • 99%+ HPLC
  • Zhuozhou Wenxi import and Export Co., Ltd

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rhapontigenin (E)-5-[2-(3-Hydroxy-4-methoxyphenyl)ethenyl]-1,3-benzenediol 3,3',5-Trihydroxy-4'-methoxy-trans-stilbene trans-1-(3,5-Dihydroxyphenyl)-2-(3-hydroxy-4-methoxyphenyl)ethylene (E)-4'-Methoxy-3,3',5-stilbenetriol (E)-5-(3-Hydroxy-4-Methoxystyryl)benzene-1,3-diol -5-(3-Hydroxy-4-methoxystyryl) 3-benzenediol 5-[(1E)-2-(3-hydroxy-4-methoxyphenyl)ethenyl]-1 5-[(1E)-2-(3-HYDROXY-4-METHOXYPHENYL)ETHENYL]-1;3-BENZENEDIOL 5-[2-(3-hydroxy-4-methoxyphenyl)ethenyl]benzene-1,3-diol Rhapontigenin > Protigenin 1,3-Benzenediol,5-[(1E)-2-(3-hydroxy-4-methoxyphenyl)ethenyl]- 3,3',5-Trihydroxy-4'-methoxy-trans-stilbene trans-1-(3,5-Dihydroxyphenyl)-2-(3-hydroxy-4-methoxyphenyl)ethylene rhapontigenin USP/EP/BP COc2ccc(/C=C/c1cc(O)cc(O)c1)cc2O 500-65-2