Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>(S)-(-)-2-Methyl-2-propanesulfinamide

(S)-(-)-2-Methyl-2-propanesulfinamide

(S)-(-)-2-Methyl-2-propanesulfinamide Structure
(S)-(-)-2-Methyl-2-propanesulfinamide structure
CAS No.
343338-28-3
Chemical Name:
(S)-(-)-2-Methyl-2-propanesulfinamide
Synonyms
(S)-2-METHYLPROPANE-2-SULFINAMIDE;TERT-BUTYL SULFINAMIDE;(S)-(-)-T-BUTYLSULFINAMIDE;S-BSN;finamide;Suprabasin;S-tert-butylsulfonamide;S- tert butyl sulfenaMide;Brilanestrant Impurity 10;(S)-(-)-TERT-BUTYLSULFINAMIDE
CBNumber:
CB0209955
Molecular Formula:
C4H11NOS
Molecular Weight:
121.2
MDL Number:
MFCD05861480
MOL File:
343338-28-3.mol
MSDS File:
SDS
Last updated:2024-10-25 16:21:11
Request For Quotation

(S)-(-)-2-Methyl-2-propanesulfinamide Properties

Melting point 97-101 °C(lit.)
alpha -4.5 º (c=1, CHCl3)
Boiling point 220.0±23.0 °C(Predicted)
Density 1.124
storage temp. 2-8°C
solubility Chloroform (Slightly), Methanol (Slightly)
pka 10.11±0.50(Predicted)
form Crystalline Powder
color White
optical activity [α]20/D 4.5°, c = 1 in chloroform
Stability store cold
InChI InChI=1/C4H11NOS/c1-4(2,3)7(5)6/h5H2,1-3H3/t7-/s3
InChIKey CESUXLKAADQNTB-SSDOTTSWSA-N
SMILES CC(C)([S@@](N)=O)C |&1:3,r|
CAS DataBase Reference 343338-28-3(CAS DataBase Reference)
FDA UNII I85YC2ZA8O

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280-P305+P351+P338-P304+P340-P405-P501A
Hazard Codes  Xi,Xn,F
Risk Statements  11-19-36/37-40
Safety Statements  16-26-36/37-24/25
WGK Germany  3
Hazard Note  Irritant/Keep Cold
TSCA  No
HS Code  29309090
NFPA 704
1
1 0

(S)-(-)-2-Methyl-2-propanesulfinamide price More Price(52)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 513210 (S)-(?)-2-Methyl-2-propanesulfinamide 97% 343338-28-3 1g $50.82 2024-03-01 Buy
Sigma-Aldrich 513210 (S)-(?)-2-Methyl-2-propanesulfinamide 97% 343338-28-3 5g $228 2024-03-01 Buy
TCI Chemical B2908 (S)-(-)-tert-Butylsulfinamide >98.0%(GC) 343338-28-3 1g $50 2024-03-01 Buy
TCI Chemical B2908 (S)-(-)-tert-Butylsulfinamide >98.0%(GC) 343338-28-3 5g $175 2024-03-01 Buy
Alfa Aesar H27115 (S)-(-)-2-Methyl-2-propanesulfinamide, 97% 343338-28-3 1g $76.65 2024-03-01 Buy
Product number Packaging Price Buy
513210 1g $50.82 Buy
513210 5g $228 Buy
B2908 1g $50 Buy
B2908 5g $175 Buy
H27115 1g $76.65 Buy

(S)-(-)-2-Methyl-2-propanesulfinamide Chemical Properties,Uses,Production

Description

Acid labile protecting groups are important in organic synthesis. The tert‐butyl group is commonly used for protection of a large variety of functional groups, e.g., acids, alcohols, phenols, and sulfonamides. Among them, s-tert-butyl sulfonamide is a chiral ligand used in pharmaceutical compositions. P, n-sulfoxide imine ligands were synthesized by condensation of s-tert-butylsulfonamide with aldehydes and ketones, and they can be used for asymmetric hydrogenation of olefins under iridium catalysis.

Physical properties

white to light yellow crystal powder

Uses

(S)-(-)-2-Methyl-2-propanesulfinamide may be used to develop benzofuran-based farnesyltransferase inhibitors as anti-cancer agents. It may also be used to prepare (20E)-N-[t-butyl-(S)-sulfinyl]-3β-(t-butyldimethylsilyloxy)-pregn-5-en-20-imine, an intermediate for the preparation of androgen receptor antagonists.

Uses

(S)-(-)-2-Methyl-2-propanesulfinamide is used in Suzuki reaction. It is also employed as a reagent for synthesizing chiral amines. It acts as a chiral auxiliary used in an asymmetric synthesis of trifluoroethylamines by conversion of trifluoroacetaldehyde to a chiral imine. It is also involved in the transformation of P,N-sulfinyl imine ligands through condensation with aldehydes and ketones, which can undergo iridium-catalyzed asymmetric hydrogenation of olefins. Further, it serves as a reagent for the preparation of chemicals and pharmaceutical intermediates.

(S)-(-)-2-Methyl-2-propanesulfinamide synthesis

60011-16-7
343338-28-3
Synthesis of (S)-(-)-2-Methyl-2-propanesulfinamide from (S)-tert-Butanethiosulfinate

(S)-(-)-2-Methyl-2-propanesulfinamide Preparation Products And Raw materials

Raw materials

Preparation Products

(S,E)-N-(2-(tert-butyldimethylsilyloxy)ethylidene)-2-methylpropane-2-sulfinamide 2-Propanesulfinamide, N-(4-chlorobutylidene)-2-methyl-, [N(E),S(S)]- (2S,3R,SS)-2-(tert-butylsulfinamido)-3-methylpent-4-enoic acid

(S)-(-)-2-Methyl-2-propanesulfinamide Suppliers

Global( 457)Suppliers
Supplier Tel Email Country ProdList Advantage
Blocksynth Pharmaceutical Technology Co.,Ltd 		0086-19817745290; +8619817745290 bd@blocksynth.com China 5657 58
Win-Win chemical CO., Limited
+86-0086-577-64498589 +86-15355981851 sales@win-winchemical.com China 14349 58
Changzhou uniringchem Co., Ltd.
+undefined13585446801 sales@uniringchem.com China 68 58
Hebei Yanxi Chemical Co., Ltd. 		+8617531190177 peter@yan-xi.com China 5858 58
Shanghai UCHEM Inc. 		+862156762820 +86-13564624040 sales@myuchem.com China 7442 58
Hebei Chuanghai Biotechnology Co,.LTD 		+86-13131129325 sales1@chuanghaibio.com China 5893 58
Hebei Weibang Biotechnology Co., Ltd 		+8617732866630 bess@weibangbio.com China 18155 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29791 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 18754 58
Beijing Cooperate Pharmaceutical Co.,Ltd 		010-60279497 sales01@cooperate-pharm.com CHINA 1803 55
Supplier Advantage
Blocksynth Pharmaceutical Technology Co.,Ltd 		58
Win-Win chemical CO., Limited
58
Changzhou uniringchem Co., Ltd.
58
Hebei Yanxi Chemical Co., Ltd. 		58
Shanghai UCHEM Inc. 		58
Hebei Chuanghai Biotechnology Co,.LTD 		58
Hebei Weibang Biotechnology Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
Beijing Cooperate Pharmaceutical Co.,Ltd 		55

Related articles

View Lastest Price from (S)-(-)-2-Methyl-2-propanesulfinamide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(S)-(-)-2-Methyl-2-propanesulfinamide pictures 2024-11-01 (S)-(-)-2-Methyl-2-propanesulfinamide
343338-28-3
 US $10.00-90.00 / g 5g 0.98 25kg Shanghai UCHEM Inc.
(S)-(-)-2-Methyl-2-propanesulfinamide pictures 2024-10-25 (S)-(-)-2-Methyl-2-propanesulfinamide
343338-28-3
 US $0.00 / KG 1KG 99% 500000kg Hebei Weibang Biotechnology Co., Ltd
2-methylpropane-2-sulfinamide pictures 2024-10-25 2-methylpropane-2-sulfinamide
343338-28-3
 US $0.00-0.00 / kg 1kg 99% 100tons Hebei Yanxi Chemical Co., Ltd.

(S)-(-)-2-Methyl-2-propanesulfinamide Spectrum

(S)-(-)-2-Methyl-2-propanesulfinamide(343338-28-3)1HNMR(S)-(-)-2-Methyl-2-propanesulfinamide(343338-28-3)FT-IR

343338-28-3((S)-(-)-2-Methyl-2-propanesulfinamide)Related Search:

N-BENZYLQUININIUM CHLORIDE TERT-BUTYLSULFONAMIDE (R)-(+)-2-METHYL-2-PROPANESULFINAMIDE,(R)-2-METHYL-2-PROPANESULFINAMIDE Trimethoprim tert-Butanol
Silver sulfate Boric acid (R)-(+)-4-Isopropyl-2-oxazolidinone (R)-(-)-4-Phenyl-2-oxazolidinone (4S)-(-)-4-Isopropyl-2-oxazolidinone
(R)-4-Benzyl-2-oxazolidinone (S)-4-Benzyl-2-oxazolidinone (S)-(+)-4-Phenyl-2-oxazolidinone Di-tert-butylphosphine Tri-tert-butylphosphine
Thionyl chloride Triisopropyl borate N-ISOPROPYL-2-NITROBENZENESULPHONAMIDE

1of4

2-METHYL-2-PROPANE-SULFINAMIDE(S-ISOMER) (S)-tert-Butylsulfinamide, (>98.0% ee), 97+% (S)-(-)-2-METHYL-2-PROPANESULPHINAMIDE (S)-(-)-2-METHYL-PROPANE-2-SULFINIC ACID AMIDE (S)-(-)-TERT-BUTYLSULFINAMIDE (S)-(-)-TERT-BUTYL SULPHINAMIDE (S)-(-)-T-BUTYLMETHYLSULFINAMIDE (S)-(-)-2-Methylpropane-2-sulphinamide 98% [S(S)]-2-Methyl-2-propanesulfinaMide 2-PropanesulfinaMide, 2-Methyl-, [S(S)]- S-BSN S- tert butyl sulfenaMide (S)-tert-Butylsulfinamide (S)-(-)-2-Methyl-2-propanesulfinamide (S)-(?)-2-Methyl-2-propanesulfinamide solution ANTI-SBSN (N-TERM) antibody produced in rabbit Suprabasin (S)-(-)-tert-Butylsulfinamide (S)-(-)-2-Methyl-2-propanesulfinamide 97% Amino(tert-butyl)sulfaniumolate (S)-(-)-2-Methyl-2-propanesulfimide (S)-2-Methyl-2-propanesulfinamide,99%e.e. (S)-(-)-t-Butylmethylsulfinamide,min.97% (S)-(-)-tert-Butyl sulphinamide 98% (S)-(-)-t-Butyl sulfinamide, 98% ee (S)-TERT-BUTANESULFINAMIDE / (S)-(-)-2-METHYL-2-PROPANESULFINAMIDE (S)-(-)-2-METHYL-2-PROPANESULFINAMIDE,98.5+% (S)-TERT-BUTYLSULFINAMIDE,97+% (>98.0% EE) (S)-(-)-t-Butylmethylsulfinamide, min. 97% (S)-tert-Butylsulfinamide, (>98.0% ee) (S)-(-)-2-Methyl-2-propanesulfinamide (S)-(-)-t-Butylsulfinamide, min. 97% (S)-TERT-BUTANESULFINAMIDE / (S)-(-)-2-METHYL-2-P S-tert-butylsulfonamide (S)-Tert butane sulfonamide 98% (S)-(-)-2-Methyl-2-propanesulfinaMide(S)-(-)-2-Methyl-2-propanesulfinaMide finamide (S)-(-)-tert-Butylsulfinamide > (S)-(-)-tert-Butylsulfinamide, 98%, for synthesis (S)-(-)-2-Methyl-2-propanesulfinamide USP/EP/BP (S)-2-METHYLPROPANE-2-SULFINAMIDE (S)-(-)-T-BUTYLSULFINAMIDE TERT-BUTYL SULFINAMIDE Brilanestrant Impurity 10 343338-28-3 343338-27-8 3423338-28-3 343338-28-2 C3H11CNOS C4H9CH3SONH2 C4H11NOS Organic Building Blocks Sulfur-Based Sulfur Compounds Sulfonamides/Sulfinamides Building Blocks Asymmetric Synthesis Chiral Auxiliaries Asymmetric Synthesis