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5-bromo-6-chloronicotinonitrile

CAS No.
71702-01-7
Chemical Name:
5-bromo-6-chloronicotinonitrile
Synonyms
5-bromo-6-chloronicotinonitrile;3-BroMo-2-chloro-5-cyanopyridine;5-Bromo-6-chloro-3-cyanopyridine;5-bromo-6-chloropyridine-3-carbonitrile;3-Pyridinecarbonitrile, 5-bromo-6-chloro-;5-Bromo-6-chloronicotinonitrile, 3-Bromo-2-chloro-5-cyanopyridine, 5-Bromo-6-chloropyridine-3-carbonitrile
CBNumber:
CB02122302
Molecular Formula:
C6H2BrClN2
Molecular Weight:
217.45
MDL Number:
MFCD11840998
MOL File:
71702-01-7.mol
Last updated:2025-07-24 18:13:49

5-bromo-6-chloronicotinonitrile Properties

Melting point 156-158°
Boiling point 265.6±35.0 °C(Predicted)
Density 1.85±0.1 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
pka -4.33±0.10(Predicted)
Appearance Off-white to light brown Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362+P364-P403+P233-P501c
RIDADR  UN2811
HazardClass  IRRITANT
HS Code  2933399990

5-bromo-6-chloronicotinonitrile price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC B415463 5-Bromo-6-chloronicotinonitrile 71702-01-7 10mg $45 2021-12-16 Buy
AK Scientific 8634AE 5-Bromo-6-chloronicotinonitrile 71702-01-7 1g $96 2021-12-16 Buy
Matrix Scientific 047390 5-Bromo-6-chloronicotinonitrile >95% 71702-01-7 500mg $25 2021-12-16 Buy
Matrix Scientific 047390 5-Bromo-6-chloronicotinonitrile >95% 71702-01-7 1g $38 2021-12-16 Buy
SynQuest Laboratories 3H37-D-0C 5-Bromo-6-chloronicotinonitrile 71702-01-7 500mg $576 2021-12-16 Buy
Product number Packaging Price Buy
B415463 10mg $45 Buy
8634AE 1g $96 Buy
047390 500mg $25 Buy
047390 1g $38 Buy
3H37-D-0C 500mg $576 Buy

5-bromo-6-chloronicotinonitrile Chemical Properties,Uses,Production

Synthesis

2-Amino-3-bromo-5-cyanopyridine

477871-32-2

5-bromo-6-chloronicotinonitrile

71702-01-7

Step 2; 5-Bromo-6-chloronicotinonitrile; To a solution of anhydrous CuCl2 (77 mg, 0.58 mmol) in acetonitrile (3 mL) was added tert-butyl cyanide (0.72 mmol). The reaction mixture was heated to 65 °C, followed by the addition of a suspension of acetonitrile (2 mL) of the above intermediate 6-amino-5-bromonicotinonitrile (96 mg, 0.48 mmol). The reaction mixture was stirred continuously for 3 hours. After completion of the reaction, the mixture was cooled to room temperature, poured into 3M HCl solution and extracted with ethyl acetate (EtOAc). The organic layer was dried with anhydrous Na2SO4 and subsequently concentrated under reduced pressure to remove the solvent. The product was purified by silica gel fast column chromatography (eluent: hexane/ethyl acetate, 2:1, v/v) to afford 5-bromo-6-chloronicotinonitrile (55 mg, 55% yield).1H-NMR (DMSO-d6, 300 MHz): δ 8.93 (s, 1H), 8.90 (s, 1H).

References

[1] Patent: WO2005/90337, 2005, A1. Location in patent: Page/Page column 43

477871-32-2
71702-01-7
Synthesis of 5-bromo-6-chloronicotinonitrile from 2-Amino-3-bromo-5-cyanopyridine

5-bromo-6-chloronicotinonitrile Preparation Products And Raw materials

5-bromo-6-chloronicotinonitrile Suppliers

Global( 86)Suppliers
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Accela ChemBio Inc.
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Amadis Chemical Company Limited
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View Lastest Price from 5-bromo-6-chloronicotinonitrile manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-bromo-6-chloronicotinonitrile pictures 2019-12-26 5-bromo-6-chloronicotinonitrile
71702-01-7
US $1.00 / KG 1KG 99% 200kg Career Henan Chemical Co

5-bromo-6-chloronicotinonitrile Spectrum

5-bromo-6-chloronicotinonitrile 3-BroMo-2-chloro-5-cyanopyridine 5-bromo-6-chloropyridine-3-carbonitrile 3-Pyridinecarbonitrile, 5-bromo-6-chloro- 5-Bromo-6-chloro-3-cyanopyridine 5-Bromo-6-chloronicotinonitrile, 3-Bromo-2-chloro-5-cyanopyridine, 5-Bromo-6-chloropyridine-3-carbonitrile 71702-01-7 71702-01-1