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Prostaglandin E1 Impurity 4

CAS No.
21003-46-3
Chemical Name:
Prostaglandin E1 Impurity 4
Synonyms
8-Iso-PGE1;OVINONIC ACID;(-)-8-epi-PGE1;8-Epiprostaglandin E1;8-epi-Prostaglandin E1;8-ISO PROSTAGLANDIN E1;Alprostadil EP Impurity F;GMVPRGQOIOIIMI-JCPCGATGSA-N;Prostaglandin (Alprostadil) EP Impurity F;9-oxo-11α,15S-dihydroxy-(8β)-prost-13E-en-1-oic acid
CBNumber:
CB0246123
Molecular Formula:
C20H34O5
Molecular Weight:
354.48
MDL Number:
MFCD00065736
MOL File:
21003-46-3.mol
MSDS File:
SDS
Last updated:2023-05-21 10:59:17

Prostaglandin E1 Impurity 4 Properties

Melting point 77-79 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3))
Boiling point 529.3±50.0 °C(Predicted)
Density 1.131±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: >100 mg/ml (from PGE1); DMSO: >50 mg/ml (from PGE1); Ethanol: >50 mg/ml (from PGE1); PBS pH 7.2: >1.6 mg/ml (from PGE1)
form A light yellow crystalline solid
pka 4.77±0.10(Predicted)
FDA UNII 84W5RE239W

Prostaglandin E1 Impurity 4 price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 13360 8-iso Prostaglandin E1 ≥98% 21003-46-3 500μg $51 2024-03-01 Buy
Cayman Chemical 13360 8-iso Prostaglandin E1 ≥98% 21003-46-3 1mg $87 2024-03-01 Buy
Cayman Chemical 13360 8-iso Prostaglandin E1 ≥98% 21003-46-3 5mg $354 2024-03-01 Buy
Cayman Chemical 13360 8-iso Prostaglandin E1 ≥98% 21003-46-3 10mg $606 2024-03-01 Buy
TRC I918350 8-IsoprostaglandinE1 21003-46-3 25mg $1125 2021-12-16 Buy
Product number Packaging Price Buy
13360 500μg $51 Buy
13360 1mg $87 Buy
13360 5mg $354 Buy
13360 10mg $606 Buy
I918350 25mg $1125 Buy

Prostaglandin E1 Impurity 4 Chemical Properties,Uses,Production

Description

Isoprostanes are a family of prostanoid molecules of non-cyclooxygenase origin. 8-iso Prostaglandin E1 (8-iso PGE1) is an isoprostane which is found in human semen at levels of 7 μg/ml. It is a pulmonary vasoconstrictor in anesthetized dogs with a potency similar to PGF.

Uses

8-Isoprostaglandin E1 has vasodilatory and electrophysiological actions porcine coronary artery. It also inhibits acetylcholine release from parasympathetic nerves innervating guinea-pig trachea mediation by prostanoid EP3 receptors.

Uses

Isoprostanes are a family of prostanoid molecules of non-cyclooxygenase origin. 8-iso Prostaglandin E1 (8-iso PGE1) is an isoprostane which is found in human semen at levels of 7 μg/ml. It is a pulmonary vasoconstrictor in anesthetized dogs with a potency similar to PGF2α.[Cayman Chemical]

Definition

ChEBI: 8-Isoprostaglandin E1 is a prostanoid.

Prostaglandin E1 Impurity 4 Preparation Products And Raw materials

Raw materials

Preparation Products

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OVINONIC ACID 9-Oxo-11aloha,15S-dihydroxy-(8beta)-prost-13E-en-1-oic acid 7-[(1S,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoic acid (-)-8-epi-PGE1 (8β,13E,15S)-11α,15-Dihydroxy-9-oxoprost-13-en-1-oic acid 8-Epiprostaglandin E1 8-epi-Prostaglandin E1 8-Iso-PGE1 9-OXO-11ALPHA,15S-DIHYDROXY-(8BETA)-PROST-13E-EN-1-OIC ACID 8-ISO PROSTAGLANDIN E1 GMVPRGQOIOIIMI-JCPCGATGSA-N 9-oxo-11α,15S-dihydroxy-(8β)-prost-13E-en-1-oic acid Prost-13-en-1-oic acid, 11,15-dihydroxy-9-oxo-, (8β,11α,13E,15S)- Alprostadil EP Impurity F f.7-[(1S,2R,3R)-3-hydroxy-2-[(1e,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoicacid(8-epiprostaglandine1), Prostaglandin (Alprostadil) EP Impurity F Prost-13-en-1-oic acid, 11,15-dihydroxy-9-oxo-, (8β,11α,13E,15S)- 21003-46-3