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1-Naphthol

1-Naphthol
1-Naphthol structure
CAS No.
90-15-3
Chemical Name:
1-Naphthol
Synonyms
nakotrb;zobaern;furro er;AR,99.0%;Nako TRB;-Napthol;ursolern;Zoba ERN;NSC 9586;1-naphtol
CBNumber:
CB0279325
Molecular Formula:
C10H8O
Formula Weight:
144.17
MOL File:
90-15-3.mol

1-Naphthol Properties

Melting point:
94-96 °C(lit.)
Boiling point:
278-280 °C(lit.)
Density 
1.224
vapor density 
4.5 (120 °C, vs air)
vapor pressure 
1 mm Hg ( 94 °C)
refractive index 
1.6224
Flash point:
125 °C
storage temp. 
Store below +30°C.
solubility 
Soluble in benzene, chloroform, ether and ethanol.
pka
9.34(at 25℃)
form 
Crystalline Flakes
color 
white to off-white
Odor
Slight phenolic odor
explosive limit
5%
Water Solubility 
436.7mg/L(25 ºC)
λmax
324nm(MeOH)(lit.)
Sensitive 
Air & Light Sensitive
Merck 
14,6383
BRN 
1817321
Stability:
Stable, but air and light sensitive - store under inert gas. Incompatible with strong bases, strong oxidizing agents.
InChIKey
KJCVRFUGPWSIIH-UHFFFAOYSA-N
CAS DataBase Reference
90-15-3(CAS DataBase Reference)
EWG's Food Scores
4-8
FDA UNII
2A71EAQ389
NIST Chemistry Reference
1-Naphthalenol(90-15-3)
EPA Substance Registry System
1-Naphthol (90-15-3)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS05,GHS06,GHS09,GHS07
Signal word  Danger
Hazard statements  H302-H311-H315-H318-H335-H411-H312
Precautionary statements  P261-P304+P340-P305+P351+P338-P405-P501a-P273-P280-P302+P352+P312-P305+P351+P338+P310-P391-P501
Hazard Codes  Xn,N
Risk Statements  21/22-37/38-41-51/53
Safety Statements  22-26-37/39-2-61
RIDADR  UN 2811 6.1/PG 3
WGK Germany  1
RTECS  QL2800000
8-23
Autoignition Temperature 510 °C
TSCA  Yes
HazardClass  6.1
PackingGroup  III
HS Code  29071510
Toxicity LD50 orally in Rabbit: 1870 mg/kg LD50 dermal Rabbit 880 mg/kg
NFPA 704
1
2 0

1-Naphthol price More Price(48)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 31097 1-Naphthol PESTANAL , analytical standard 90-15-3 1g $34.9 2021-12-16 Buy
Sigma-Aldrich 8.22289 1-Naphthol for synthesis 90-15-3 250 g $35.24 2021-12-16 Buy
Sigma-Aldrich 1.06223 1-Naphthol GR for analysis 90-15-3 50 g $91.57 2021-12-16 Buy
Sigma-Aldrich 8.22289 1-Naphthol for synthesis 90-15-3 1 kg $115.62 2021-12-16 Buy
Sigma-Aldrich 33420 1-Naphthol puriss. p.a., Reag. Ph. Eur., ≥99% (GC) 90-15-3 100g-r $129 2021-12-16 Buy

1-Naphthol Chemical Properties,Uses,Production

Description

1-Naphthol, or α-naphthol, is a fluorescent organic compound with the formula C10H7OH. It is a white solid. It is an isomer of 2-naphthol differing by the location of the hydroxyl group on the naphthalene ring. The naphthols are naphthalene homologues of phenol, with the hydroxyl group being more reactive than in the phenols. Both isomers are soluble in simple alcohols, ethers, and chloroform. They are precursors to a variety of useful compounds. Naphthols (both 1 and 2 isomers) are used as biomarkers for livestock and humans exposed to polycyclic aromatic hydrocarbons.
α-naphtol, combined with epichlorhydrine and sodium hydroxide to form alpha-naphtyl glycidyl ether, caused sensitization in one of three workers in a chemical plant.

Chemical Properties

Pale grey to brown solid

Uses

1-Naphthol is used as a precursor in the manufacturing of various azo dyes and pharmaceuticals such as nadolol. It is used as biomarkers. It is used in analytical chemistry as Molisch’s reagent (1-naphthol dissolved in ethanol) for checking the presence of carbohydrates. It plays an essential role with sodium hypobromite to detect the presence of arginine in proteins, which is called as Sakaguchi test.

Uses

1-Naphthol is used as a precursor in the manufacturing of various azo dyes and pharmaceuticals such as nadolol. It is used as biomarkers. It is used in analytical chemistry as Molisch?s reagent (1-naphthol dissolved in ethanol) for checking the presence of carbohydrates. It plays an essential role with sodium hypobromite to detect the presence of arginine in proteins, which is called as Sakaguchi test.

Application

1-Naphthol is a hydroxyl-aromatic compound. It has been used as a prooxidant to analyze its ability to induce hemolysis in a zebrafish G6PD (glucose-6-phosphate dehydrogenase) deficiency model.

Definition

ChEBI: A naphthol carrying a hydroxy group at position 1.

Synthesis Reference(s)

Synthetic Communications, 21, p. 379, 1991 DOI: 10.1080/00397919108016759
Journal of the American Chemical Society, 107, p. 493, 1985 DOI: 10.1021/ja00288a037

General Description

1-Naphthol, a metabolite of carbaryl and naphthanlene. It is formed by spontaneous reaction from (1R, 2S)-Naphthalene epoxide followed to form 1, 4-Dihydroxynaphthalene.

Hazard

Toxic by ingestion and skin absorption.

Contact allergens

Alpha-naphthol can be used in dye manufacture and is classified as a hair dye. Combined with epichlorhydrin and NaOH to form alpha-naphthyl glycidyl ether, it caused sensitization in one of three workers in a chemical plant.

Safety Profile

Poison by ingestion and intraperitoneal routes. Moderately toxic by skin contact. An experimental teratogen. Experimental reproductive effects. A severe eye and skin irritant. Mutation data reported. Ingestion of large amounts can cause nephritis, vomiting, diarrhea, circulatory collapse, anemia, convulsions, and death. Can cause kidney irritation and injury to cornea and lens of the eye. Combustible when exposed to heat or flame. When heated to decomposition it emits acrid smoke and irritating fumes.

Purification Methods

Sublime 1-naphthol, then crystallise it from aqueous MeOH (charcoal), aqueous 25% or 50% EtOH, *C6H6, cyclohexane, heptane, CCl4 or H2O. Dry it over P2O5 in vacuo. The 4-nitrobenzoate has m 143o (from EtOH). [Shizuka et al. J Am Chem Soc 107 7816 1985, Beilstein 8 H 596, 6 IV 4208.]

1-Naphthol Preparation Products And Raw materials

Raw materials

Preparation Products


1-Naphthol Suppliers

Global( 521)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Mascot I.E.Co .,Ltd.
+8613584504415 +86-0519-85010339
info@mascot-ie.com China 327 58
Capot Chemical Co.,Ltd.
+86(0)13336195806 +86-571-85586718
+86-571-85864795 sales@capotchem.com China 20012 60
Henan DaKen Chemical CO.,LTD.
+86-371-66670886
info@dakenchem.com China 15427 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com China 22607 55
Hangzhou FandaChem Co.,Ltd.
008615858145714
+86-571-56059825 fandachem@gmail.com CHINA 9010 55
Guangzhou PI PI Biotech Inc
+8618371201331
020-81716319 sales@pipitech.com;87478684@qq.com China 3283 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-0371-55982848
sales@coreychem.com China 29954 58
NINGBO INNO PHARMCHEM CO., LTD.
13867897135
sales@nbinno.com CHINA 925 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 linda@hubeijusheng.com CHINA 28229 58

View Lastest Price from 1-Naphthol manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2022-01-14 1-Naphthol
90-15-3
US $0.00 / Kg/Bag 1KG 99% 2000mt/year Jinan Finer Chemical Co., Ltd
2021-11-30 1-Naphthol
90-15-3
US $16.00 / KG 25Kg/Drum 99% 1000T Baoji Guokang Bio-Technology Co., Ltd.
2021-08-14 1-Naphthol
90-15-3
US $16.00 / KG 1g 99.9% 500000kgs Shijiazhuang tongyang Import and Export Co., LTD

1-Naphthol Spectrum


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