CHOLIC-2,2,4,4-D4 ACID
- CAS No.
- 116380-66-6
- Chemical Name:
- CHOLIC-2,2,4,4-D4 ACID
- Synonyms
- Cholic-d4 Acid;2H4]-Cholic Acid;Cholic acid-2,2,4,4-d;Cholic Acid -[d4] (Solution);Cholic Acid-d4 MaxSpec? Standard;5β-cholanic acid-3α,7α,12α-triol-2,2,4,4-d4;CHOLIC ACID (2,2,4,4-D4, 98%) 100 UG/ML IN METHANOL
- CBNumber:
- CB0334837
- Molecular Formula:
- C24H36D4O5
- Molecular Weight:
- 412.6
- MDL Number:
- MFCD00209701
- MOL File:
- 116380-66-6.mol
- MSDS File:
- SDS
| Melting point | 200-201°C (lit.) |
|---|---|
| storage temp. | Store at -20°C |
| solubility | DMF: 30 mg/ml,DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml,DMSO: 20 mg/ml,Ethanol: 20 mg/ml |
| form | Solid |
| color | White to Off-White |
| FDA UNII | 88X15G5Z03 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H370 | |||||||||
| Precautionary statements | P210-P233-P240-P241-P242-P243-P260-P264-P270-P280-P303+P361+P353-P307+P311-P321-P370+P378-P403+P235-P405-P501 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
CHOLIC-2,2,4,4-D4 ACID price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 614149 | Cholic acid-2,2,4,4-d 98 atom % D, 98% (CP) | 116380-66-6 | 500mg | $1670 | 2024-03-01 | Buy |
| Cayman Chemical | 20849 | Cholic Acid-d4 ≥95% | 116380-66-6 | 1mg | $81 | 2024-03-01 | Buy |
| Cayman Chemical | 20849 | Cholic Acid-d4 ≥95% | 116380-66-6 | 5mg | $120 | 2024-03-01 | Buy |
| Cayman Chemical | 20849 | Cholic Acid-d4 ≥95% | 116380-66-6 | 10mg | $223 | 2024-03-01 | Buy |
| TRC | C432603 | CholicAcid-d4 | 116380-66-6 | 50mg | $470 | 2021-12-16 | Buy |
CHOLIC-2,2,4,4-D4 ACID Chemical Properties,Uses,Production
Description
Cholic acid-d4 is intended for use as an internal standard for the quantification of cholic acid by GC- or LC-MS. Cholic acid is a primary bile acid. It is formed from cholesterol via a multistep process catalyzed by the cytochrome P450 (CYP) isoforms CYP7A1, CYP8B1, and CYP27A1. Cholic acid is conjugated to glycine or taurine by bile acid-CoA:amino acid N-acyltransferase (BAAT) to produce glycocholic acid (GCA; ) and taurocholic acid (TCA; ), respectively, in the liver, and is transformed into the secondary bile acid deoxycholic acid (DCA; ) by intestinal microbiota. It induces C. difficile colony formation in an agar dilution assay when used at a concentration of 0.1% w/v. Dietary administration of cholic acid (0.4% w/w) increases serum cholesterol levels, biliary phospholipid secretion, and fecal DCA levels in rats.
Uses
Cholic Acid-d4 is a labelled analog of Cholic acid (C432600) which is a choleretic produced by, and isolated from liver cells.
Definition
ChEBI: Cholic acid-2,2,4,4-d4 is a bile acid.
CHOLIC-2,2,4,4-D4 ACID Preparation Products And Raw materials
Raw materials
Preparation Products
CHOLIC-2,2,4,4-D4 ACID Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Shanghai Beiwanta Biotechnology Co., Ltd. | 021-67187366 19901745723 | info@bwtlab.com | China | 9240 | 58 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 18521732826; | market@aladdin-e.com | China | 25015 | 65 |
| Clearsynth Labs Limited | +91-22-26355700 | info@clearsynth.com | India | 9685 | 58 |
| TianJin Alta Scientific Co., Ltd. | 022-65378550-8551 | contact@altascientific.com | China | 2773 | 58 |
| ChemStrong Scientific Co.,Ltd | 0755-66853366 13670046396 | sales@chem-strong.com | China | 17982 | 56 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Artis Biotech Co. Ltd. | 19138486554 18582380095 | sales@artisbio.com | China | 3066 | 58 |
| Wuhan Netcom Electronic Commerce Limited | 18064670521 | 2355935187@ycphar.com | China | 4887 | 58 |