Tetrabutylammonium hydrogen sulfate
- CAS No.
- 32503-27-8
- Chemical Name:
- Tetrabutylammonium hydrogen sulfate
- Synonyms
- TBAHS;TETRABUTYLAMMONIUM BISULFATE;IPC-TBA-HS;TETRABUTYLAMMONIUM HYDROGEN SULPHATE;hydrogen sulfate,tetrabutylazanium;ammonium hydrog;TETRA-N-BUTYLAMMONIUM HYDROGEN SULPHATE;Tetrabutylammonium Hydrogen Sulfate [Reagent for Ion-Pair Chromatography];fate;en suL
- CBNumber:
- CB0414623
- Molecular Formula:
- C16H37NO4S
- Molecular Weight:
- 339.53
- MDL Number:
- MFCD00011637
- MOL File:
- 32503-27-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Tetrabutylammonium bisulfate solution suitable for ion pair chromatography, LiChropur?, concentrate, ampule | 98479 | 6x1amp | $444 |
| Tetrabutylammonium bisulfate suitable for ion pair chromatography, LiChropur?, ≥99.0% | 86853 | 10g | $194 |
| Tetrabutylammonium bisulfate suitable for ion pair chromatography, LiChropur?, ≥99.0% | 86853 | 10x1g | $620 |
| Tetrabutylammonium bisulfate suitable for ion pair chromatography, LiChropur?, ≥99.0% | 86853 | 50g | $752 |
| Tetra-n-butylammonium hydrogen sulfate for synthesis | 8.18858 | 100g | $148 |
| More product size | |||
| Melting point | 171-174 °C |
|---|---|
| Boiling point | 213.3-593.92℃[at 101 325 Pa] |
| bulk density | 650kg/m3 |
| Density | 1.01 |
| vapor pressure | 0Pa at 25℃ |
| storage temp. | Store below +30°C. |
| solubility | H2O: soluble10% (w/v), clear, colorless |
| form | Solution |
| Specific Gravity | 1.01 |
| color | White to beige |
| PH | 1-2 (100g/l, H2O, 20℃) |
| Odor | Amine like |
| PH Range | 1 - 2 |
| Water Solubility | Soluble |
| Sensitive | Hygroscopic |
| λmax |
λ: 210 nm Amax: 0.06 λ: 220 nm Amax: 0.05 λ: 230 nm Amax: 0.03 λ: 260 nm Amax: 0.02 λ: 500 nm Amax: 0.02 |
| BRN | 3599663 |
| Stability | Stable, but moisture sensitive. Incompatible with strong oxidizing agents. |
| InChI | 1S/C16H36N.H2O4S/c1-5-9-13-17(14-10-6-2,15-11-7-3)16-12-8-4;1-5(2,3)4/h5-16H2,1-4H3;(H2,1,2,3,4)/q+1;/p-1 |
| InChIKey | SHFJWMWCIHQNCP-UHFFFAOYSA-M |
| SMILES | OS([O-])(=O)=O.CCCC[N+](CCCC)(CCCC)CCCC |
| LogP | 0.96 at 25℃ |
| CAS DataBase Reference | 32503-27-8(CAS DataBase Reference) |
| NIST Chemistry Reference | Tetrabutylammonium hydrogen sulfate(32503-27-8) |
| EPA Substance Registry System | Tetrabutylammonium sulfate (1:1) (32503-27-8) |
| UNSPSC Code | 12352107 |
| NACRES | NB.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H314-H412 | |||||||||
| Precautionary statements | P260-P273-P280-P301+P312-P303+P361+P353-P305+P351+P338 | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 36/37/38-22 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 8-10 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29239000 | |||||||||
| Storage Class | 8A - Combustible corrosive hazardous materials | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Chronic 3 Eye Dam. 1 Skin Corr. 1 |
|||||||||
| NFPA 704 |
|
Tetrabutylammonium hydrogen sulfate price More Price(77)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 98479 | Tetrabutylammonium bisulfate solution suitable for ion pair chromatography, LiChropur?, concentrate, ampule | 32503-27-8 | 6x1amp | $444 | 2026-04-30 | Buy |
| Sigma-Aldrich | 86853 | Tetrabutylammonium bisulfate suitable for ion pair chromatography, LiChropur?, ≥99.0% | 32503-27-8 | 10g | $194 | 2026-04-30 | Buy |
| Sigma-Aldrich | 86853 | Tetrabutylammonium bisulfate suitable for ion pair chromatography, LiChropur?, ≥99.0% | 32503-27-8 | 10x1g | $620 | 2026-04-30 | Buy |
| Sigma-Aldrich | 86853 | Tetrabutylammonium bisulfate suitable for ion pair chromatography, LiChropur?, ≥99.0% | 32503-27-8 | 50g | $752 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.18858 | Tetra-n-butylammonium hydrogen sulfate for synthesis | 32503-27-8 | 100g | $148 | 2026-04-30 | Buy |
Tetrabutylammonium hydrogen sulfate Chemical Properties,Uses,Production
Chemical Properties
It is a stable, hygroscopic, white powder.
Uses
A compound that displays antibacterial properties due to the presence of the quaternary amine and the counter ion. Tetrabutylammonium hydrogen sulfate is an ion pairing reagent that is used in liquid chromatography. It is frequently utilized in the analysis of pharmaceutical compounds and metabolites.
Uses
Phase transfer catalyst Tetra-n-butylammonium hydrogen sulfate shows antibacterial properties due to the presence of the quaternary amine and the counter ion. It serves as a phase-transfer catalyst, surface-active agent, solvent, intermediate, active ingredient for conditioners, antistatic agent, detergent sanitizers, softener for textiles and paper products, emulsifying agents and pigment dispersers. Tetrabutylammonium hydrogensulfate is used as a cocatalyst in the synthesis of propionic acid and the ketones by hydrocarboxylation of ethylene. It is also used as an efficient catalyst in the N-alkylation reactions of benzanilides, cyclization of beta-amino acids to beta-lactams, conversion of nitriles to amides, dehydrohalogenation of aryl 2-haloethyl ethers to give vinyl ethers and in the oxidation of alcohols.
Preparation
Tetrabutylammonium hydrogen sulfate can be prepared from tetrabutylammonium azide by treating it with potassium hydrogen sulfate and 10% aqueous sulfuric acid in aqueous medium or from tetrabutylammonium thiocyanate by treating it with relatively concentrated sulfuric acid (70%) at 75 °C.
General Description
Tetrabutylammonium hydrogensulfate, a quaternary ammonium salt, is a phase-transfer reagent. It It serves as solvent for the dissolution of ruthenium(II) complex fac-[Ru(CO)2(H2O)3(C(O)C2H5)][CF3SO3]. It participates as a cocatalyst in the reaction medium for the preparation of alternating polyketones and propionic acid.
Purification Methods
The sulfate crystallises from acetone. It has been used as a phase transfer catalyst.
References
[1] H. N. KARADE M. P K M Sathe. An efficient synthesis of 1, 8-dioxo-octahydroxanthenes using tetrabutylammonium hydrogen sulfate[J]. Arkivoc, 2007, 2007 1. DOI:10.3998/ARK.5550190.0008.D28.
[2] A. J. PARDEY. New media in homogeneous catalysis: wet sodium or tetrabutylammonium hydrogensulfate salts for reppe syntheses catalyzed by a ru(ii) carbonyl complex[J]. Journal of Coordination Chemistry, 2004, 57 1: 871-882. DOI:10.1080/00928970410001721998.
[3] A. J. PARDEY. Hydrocarboxylation and stepwise alternating oligomerization of carbon monoxide and ethylene catalyzed by cis-[Rh(CO)2(amine)2](PF6) complexes in a wet liquid tetrabutylammonium hydrogensulfate[J]. Polyhedron, 2004, 23 1: 1677-1683. DOI:10.1016/J.POLY.2004.03.023.
[4] NEETU TEWARI Rama P T Namrata Dwivedi. Tetrabutylammonium hydrogen sulfate catalyzed eco-friendly and efficient synthesis of glycosyl 1,4-dihydropyridines[J]. Tetrahedron Letters, 2004, 45 49: Pages 9011-9014. DOI:10.1016/j.tetlet.2004.10.057.
Tetrabutylammonium hydrogen sulfate Preparation Products And Raw materials
Raw materials
Preparation Products
1of3
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5235 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20124 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3692 | 58 |
| Hebei Longbang Technology Co., LTD | +86-18633929156 | admin@hblongbang.com | China | 972 | 58 |
| HebeiShuoshengImportandExportco.,Ltd | +86-18532138899 | L18532138899@163.com | China | 939 | 58 |
| HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | +86-15350851019; +8615350851019 | admin@86-ss.com | China | 999 | 58 |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 880 | 50 |
View Lastest Price from Tetrabutylammonium hydrogen sulfate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-06 | Tetrabutylammonium hydrogen sulfate
32503-27-8
|
US $110.00-70.00 / kg | 1kg | 99% | 5000 | HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | |
 |
2026-04-30 | Tetrabutylammonium hydrogen sulfate
32503-27-8
|
US $0.00 / KG | 25KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2026-03-20 | LACTALBUMIN HYDROLYSATE
32503-27-8
|
US $0.00-0.00 / kg | 1kg | 99% | 100 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-
- Tetrabutylammonium hydrogen sulfate
32503-27-8
- US $110.00-70.00 / kg
- 99%
- HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
-
- Tetrabutylammonium hydrogen sulfate
32503-27-8
- US $0.00 / KG
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- LACTALBUMIN HYDROLYSATE
32503-27-8
- US $0.00-0.00 / kg
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
