BETAZOLE HYDROCHLORIDE
- CAS No.
- 138-92-1
- Chemical Name:
- BETAZOLE HYDROCHLORIDE
- Synonyms
- histalog;Histimin;gastramine;Histalog (TN);betazolehydrochloride;betazoledihydrochloride;2-(3-Pyrazolyl)ethylamin;ametazoledihydrochloride;Betazole hydrochloride (JAN);BETAZOLE HYDROCHLORIDE (200 MG)
- CBNumber:
- CB0501633
- Molecular Formula:
- C5H11Cl2N3
- Molecular Weight:
- 184.06694
- MDL Number:
- MFCD01693704
- MOL File:
- 138-92-1.mol
| Melting point | 224-226° |
|---|---|
| storage temp. | Store at -20°C |
| solubility | DMSO: 37 mg/mL (201.01 mM);Ethanol: 18 mg/mL (97.79 mM) |
| Water Solubility | Water: 37 mg/mL (201.01 mM) |
| EWG's Food Scores | 1 |
| FDA UNII | 66ABP6C83F |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
| HS Code | 2933199090 |
BETAZOLE HYDROCHLORIDE price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B276680 | BetazoleDihydrochloride | 138-92-1 | 2.5mg | $160 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FP126823 | Betazole dihydrochloride | 138-92-1 | 250mg | $172.5 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FP126823 | Betazole dihydrochloride | 138-92-1 | 2g | $867 | 2021-12-16 | Buy |
| Apolloscientific | OR471576 | 2-(3-Pyrazolyl)ethanaminedihydrochloride | 138-92-1 | 5g | $1827 | 2021-12-16 | Buy |
| Matrix Scientific | 077451 | [2-(1H-Pyrazol-3-yl)ethyl]amine dihydrochloride | 138-92-1 | 5g | $2310 | 2021-12-16 | Buy |
BETAZOLE HYDROCHLORIDE Chemical Properties,Uses,Production
Originator
Histalog,Lilly,US,1953
Uses
Betazole Hydrochloride is a histamine H2 receptor agonist that is used as a gastric stimulant for the investigation of gastric secretion activity.
Definition
ChEBI: The dihydrochloride salt of betazole.
Manufacturing Process
A solution of 55 grams (1.1 mol) of hydrazine hydrate in 100 ml of methanol was cooled in a water bath and stirred while a solution of 48 grams (0.50 mol) of pure γ-pyrone in 100 ml of methanol was added over a period of about 15 minutes. After the addition was complete, the solution was allowed to stand at room temperature for about 1 hour, and was placed in a 1 liter hydrogenation bomb. 25 ml of liquid ammonia were added cautiously with stirring, followed by about 15 cc of Raney nickel catalyst. The bomb was charged with hydrogen to 1,800 pounds pressure, heated to 90°C and agitated. The quantity of hydrogen required to convert the hydrazone into the desired aminoethylpyrazole was taken up in about 3 hours. The bomb was cooled and opened, and the contents filtered. The filtrate was evaporated under reduced pressure to remove the methanol and the residual liquid was distilled under reduced pressure, whereby there were obtained 44.5 grams (81% yield) of 3-β-aminoethylpyrazole boiling at 118°-123°C at a pressure of 0.5 mm of Hg.
brand name
Histalog (Lilly).
Therapeutic Function
Diagnostic aid (gastric secretion)
BETAZOLE HYDROCHLORIDE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21149 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 9320 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42057 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | sales@accelachem.com | China | 11660 | 64 |
| Sinopharm Chemical Reagent Co,Ltd. | 86-21-63210123 | sj_scrc@sinopharm.com | China | 9823 | 79 |
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