Xylazine Hydrochloride

Xylazine Hydrochloride Properties

Melting point	150-164?C (dec.)
storage temp.	2-8°C
solubility	≥12.84 mg/mL in DMSO; ≥24.1 mg/mL in EtOH; ≥24.15 mg/mL in H2O
color	White to Almost white
Water Solubility	Soluble in water
Merck	14,10080
BRN	6448471
InChI	InChI=1S/C12H16N2S.ClH/c1-9-5-3-6-10(2)11(9)14-12-13-7-4-8-15-12;/h3,5-6H,4,7-8H2,1-2H3,(H,13,14);1H
InChIKey	QYEFBJRXKKSABU-UHFFFAOYSA-N
SMILES	N(C1SCCCN=1)C1C(=CC=CC=1C)C.Cl
CAS DataBase Reference	23076-35-9(CAS DataBase Reference)
FDA UNII	NGC3S0882S

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS06

Signal word

Danger

Hazard statements

H301-H315-H319-H335

Precautionary statements

P261-P264-P270-P301+P310-P302+P352-P305+P351+P338

Hazard Codes

T

Risk Statements

25-36/37/38

Safety Statements

26-36/37/39-45

RIDADR

2811

WGK Germany

-

RTECS

XJ0776350

HazardClass

6.1(b)

PackingGroup

III

HS Code

29349990

Toxicity

dog,LD50,intramuscular,47mg/kg (47mg/kg),Clinical Toxicology. Vol. 15, Pg. 281, 1979.

NFPA 704

	0
2		0

Xylazine Hydrochloride price More Price(41)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	PHR3264	Xylazine Hydrochloride pharmaceutical secondary standard, certified reference material	23076-35-9	500MG	$173	2024-03-01	Buy
Sigma-Aldrich	46995	Xylazine hydrochloride VETRANAL , analytical standard	23076-35-9	100mg	$60.1	2024-03-01	Buy
Sigma-Aldrich	1720429	Xylazine hydrochloride United States Pharmacopeia (USP) Reference Standard	23076-35-9	200mg	$436	2024-03-01	Buy
TCI Chemical	X0059	Xylazine Hydrochloride >98.0%(HPLC)(T)	23076-35-9	5g	$100	2024-03-01	Buy
TCI Chemical	X0059	Xylazine Hydrochloride >98.0%(HPLC)(T)	23076-35-9	25g	$302	2024-03-01	Buy

Product number	Packaging	Price	Buy
PHR3264	500MG	$173	Buy
46995	100mg	$60.1	Buy
1720429	200mg	$436	Buy
X0059	5g	$100	Buy
X0059	25g	$302	Buy

Xylazine Hydrochloride Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

Xylazine Hydrochloride is an alpha-2 agonist with sedative, analgesic, and muscle relaxant properties. It is approved for use in dogs,cats,horses,deer,and elk. This agent causes vomiting in a large percentage of cats and in some dogs. Xylazine is antagonized by yohimbine. It produces effective analgesia in horses and is often used for treating the pain associated with colic and for sedation for minor procedures.It is also used in combination with ketamine for short-term feld procedures in horses,such as castration and suturing of extensive wounds，because this combination usually produces 15 to 20 minutes of recumbency. Extralabel use of xylazine for cesarean sections in cattle and other surgical procedures is common. Xylazine Hydrochloride is used in cats and dogs as a tranquilizer and in combination with other injectable agents for surgical procedures.

Definition

ChEBI: Xylazine hydrochloride is the hydrochloride salt of xylazine. It is used as a sedative, analgesic, and muscle relaxant in veterinary medicine. It has a role as an alpha-adrenergic agonist, an analgesic, an emetic, a muscle relaxant and a sedative. It contains a xylazine(1+).

brand name

Rompun (Bayer Animal Health).

Biological Activity

Xylazine Hydrochloride is a strong agonist of α2-adrenoceptor [1].xylazine hcl has been reported to stimulate the proliferation of rat thymocytes in vivo (at doses of 2.5 mg/kg and 5 mg/kg) and in vitro (at concentration of 5 mm) [2]. in the analgesic testing, xylazine has shown a significant prolongation of the analgesic effects in the presence of naloxine in 40 and 50 mins. in addition, xylazine has also shown the inhibitory effect in the mouse vas deferens bioassay with the ic50 value of 18nm. furthermore, xylazine has displayed a potent specific [3h]-dihydromorphine binding inhibition with the ic50 value of 8μm in opiate receptor binding test [1].

Biochem/physiol Actions

Xylazine is used as a sedative in goats as it is safe, active and a cheap drug. It is a centrally acting drug, which exhibits muscle relaxant and analgesic properties.

Side effects

Respiratory depression, low blood pressure, slowed heart rate, hypothermia, pupil constriction and, sometimes, high blood sugar levels.
The pupil constriction and respiratory depression are particularly of concern, as these are very common and widely understood effects of an opioid overdose.
Severe, necrotic skin ulcerations are the most striking side effect of xylazine. Notably, while these skin ulcerations may appear at the site of injection, they may appear at a completely different site on the body altogether. Soft tissue infections are often associated with IV drug use of more conventional illicit substances such as opioids, but these are almost always located at the injection site.

Veterinary Drugs and Treatments

Xylazine Hydrochloride is approved for use in dogs, cats, horses, deer, and elk. It is indicated in dogs, cats, and horses to produce a state of sedation with a shorter period of analgesia, and as a preanesthetic before local or general anesthesia. Because of the emetic action of xylazine in cats, it is occasionally used to induce vomiting after ingesting toxins.

References

[1] s. browning, d.lawrence1, a.livingston & b.morris. interaction of drugs active at opiate receptors and drugs active at α2-adrenoceptors on various test systems
[2] colić m1, cupić v, pavicić l, vucević d, varagić vm. xylazine, an alpha 2-adrenergic agonist, modulates proliferation of rat thymocytes in vivo and in vitro. methods find exp clin pharmacol. 2000 sep;22(7):557-62.

Xylazine Hydrochloride Preparation Products And Raw materials

Raw materials

2,6-Dimethylaniline Triethylamine Carbon disulfide 3-Aminopropanol

Preparation Products

Xylazine Hydrochloride Suppliers

Global( 271)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Aosiris new Material Technology Co., LTD	+8615139564871	wrjmoon2000@163.com	China	354	58
Shanghai UCHEM Inc.	+862156762820 +86-13564624040	sales@myuchem.com	China	6711	58
Shandong Hanjiang Chemical Co., Ltd	+86-0533-2066820 +8618369939125	hanson@sdhanjiang.com	China	1527	58
Wuhan Boyuan Import & Export Co., LTD	+8615175982296	Mike@whby-chem.com	China	974	58
Xiamen Wonderful Bio Technology Co., Ltd.	+8613043004613	Sara@xmwonderfulbio.com	China	305	58
Shaanxi Franta Biotechnology Co., Ltd	+86-13082019107 +86-13082019107	admin@flanderff.com	China	229	58
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9352	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418679 +86-18949832763	info@tnjchem.com	China	2989	55
Shanxi Naipu Import and Export Co.,Ltd	+86-13734021967 +8613734021967	kaia@neputrading.com	China	1011	58

Supplier	Advantage
Shanghai Aosiris new Material Technology Co., LTD	58
Shanghai UCHEM Inc.	58
Shandong Hanjiang Chemical Co., Ltd	58
Wuhan Boyuan Import & Export Co., LTD	58
Xiamen Wonderful Bio Technology Co., Ltd.	58
Shaanxi Franta Biotechnology Co., Ltd	58
Hangzhou FandaChem Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
Hefei TNJ Chemical Industry Co.,Ltd.	55
Shanxi Naipu Import and Export Co.,Ltd	58

View Lastest Price from Xylazine Hydrochloride manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-15	Xylazine hydrochloride 23076-35-9	US $1.00 / g	10g	99	5ton/month	ANHUI SHENGZHIKAI BIOTECHNOLOGY CO.,LTD
2024-04-12	Xylazine Hydrochloride 23076-35-9	US $3.00-1.00 / kg	1kg	99.9%	10 tons	Shanghai Aosiris new Material Technology Co., LTD
2024-04-12	Xylazine hydrochloride 23076-35-9	US $0.00 / kg	1kg	0.99	10T	Shandong Hanjiang Chemical Co., Ltd

Xylazine hydrochloride
23076-35-9
US $1.00 / g
99
ANHUI SHENGZHIKAI BIOTECHNOLOGY CO.,LTD

Xylazine Hydrochloride
23076-35-9
US $3.00-1.00 / kg
99.9%
Shanghai Aosiris new Material Technology Co., LTD

Xylazine hydrochloride
23076-35-9
US $0.00 / kg
0.99
Shandong Hanjiang Chemical Co., Ltd

Xylazine Hydrochloride Spectrum

Xylazine Hydrochloride(23076-35-9)MS Xylazine Hydrochloride(23076-35-9)¹HNMR Xylazine Hydrochloride(23076-35-9)IR1 Xylazine Hydrochloride(23076-35-9)IR2

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2-[2,6-DIMETHYLPHENYLAMINO]-4H-5,6-DIHYDROTHIAZINE HYDROCHLORIDE 2-[(2,6-DIMETHYLPHENYL)AMINO]-5,6-DIHYDRO-4H-1,3-THIAZINE HYDROCHLORIDE XYLAZINE HYDROCHLORIDE VETRANAL, 100 MG XYLAZINE HYDROCHLORIDE, USP STANDARD XYLAZINE HYDROCHLORIDE, EP STANDARD XYLAZINE HYDROCHLORIDE, MM(CRM STANDARD) XYLAZINE HYDROCHLORIDE, IMP. A (EP): 2,6-DIMETHYLANILINE MM(CRM STANDARD) Rompun[R] Xylazine Hydrochloride (200 mg) celactal rompun xylazinechloride 4H-1,3-Thiazin-2-amine, N-(2,6-dimethylphenyl)-5,6-dihydro-, monohydrochloride XYLAZINEHYDROCHLORIDE,USP N-(2,6-Dimethylphenyl)5,6-dihydro-4H-1,4-thiazine-2-amine hydrochloride (Xylazine) 2-(2,6-Dimethylphenylamino)-5,6-dihydro-4H-thiazine hydrochloride (5,6-Dihydro-4H-1,3-thiazin-2-yl)(2,6-dimethylphenyl)amine Hydrochloride Xylazine hydrochloride,2-(2,6-Dimethylphenylamino)-5,6-dihydro-4H-thiazine hydrochloride (5,6-Dihydro-4H-1,3-thiazin-2-yl)(2,6-dimethylphenyl)amine Hydrochloride 2-[(2,6-Dimethylphenyl)amino]-5,6-dihydro-4H-1,3-thiazine Hydrochloride N-(2,6-DiMethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-aMine · HCl, (5,6-Dihydro-4H-[1,3]thiazin-2-yl)-(2,6-diMethyl-phenyl)-aMine · HCl N-(2,6-diMethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-aMine hydrochloride 4H-1,3-Thiazin-2-amine, N-(2,6-dimethylphenyl)-5,6-dihydro-, hydrochloride (1:1) (5,6-DIHYDRO-4H-[1,3]THIAZIN-2-YL)-(2,6-DIMETHYLPHENYL)-AMINE HCL (5,6-DIHYDRO-4H-1,3-THIAZIN-2-YL)(2,6-DIMETHYLPHENYL)AMINE HYDROCHLORIDE N-(2,6-DIMETHYLPHENYL)-5,6-DIHYDRO-4H-1,3-THIAZIN-2-AMINE HCL XYLAZINE HYDROCHLORIDE 2-(2,6-dimethylphenylamino)-4h-5,6-dihydro-1,3-thiazinehydrochloride 3-thiazin-2-amine,n-(2,6-dimethylphenyl)-5,6-dihydro-4h-monoydrochloride 3-thiazine,5,6-dihydro-2-(2,6-xylidino)-4h-monohydrochloride 5,6-dihydro-2-(2,6-xylidino)-4h-1,3-thiazinemonohydrochloride bay1470hydrochloride bay-va1470 Xylazine hydrochloride CRS Xylazine Hydrochloride Standard High quality Xylazine/Xylazine Hydrochloride High purity Xylazine Hydrochloride Toluene thiazide hydrochloride Hydrochloride Powder Xylazine Hydrochloride Basic information Xylazine HCL powder Xylazine hydrochloride white powder 99% Xylazine Hydrochloride USP/EP/BP xylazine crystal Horse tranquilizer 23076-35-9 xylazine hcl 23076-35-9 xylazine hcl Xylazine HCl (BAY 1470 HCl) Xylazine HydrochlorideQ: What is Xylazine Hydrochloride Q: What is the CAS Number of Xylazine Hydrochloride Q: What is the storage condition of Xylazine Hydrochloride Q: What are the applications of Xylazine Hydrochloride N-(2,6-Dimethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine hydrochloride (1:1) High Purity CAS 23076 35 9 Xylazine Hydrochloride 99% White Powder Xylazine Hydrochloride CAS 23076-35-9 with good price Xylazine Hydrochloride (1720429) 4H-1,3-Thiazin-2-amine 2,6-bis(1-methylethyl)benzene-1,4-dione 245-417-0 HYDROGEN XYLAZINE CHLORIDE Xylazine hydrochlorid 2-(2,6-DIMETHYLPHENYLAMINO)-5,6-DIHYDRO-4H-THIAZINE HYDROCHLORIDE XYLAZINE HCL XYLAZIN HYDROCHLORIDE