5,7-Dimethylisatin
- CAS No.
- 39603-24-2
- Chemical Name:
- 5,7-Dimethylisatin
- Synonyms
- AKOS BC-1645;5,7-Dimethylsatin;5,7-Dimethylisatin;TIMTEC-BB SBB005805;5,7-dimethylisatine;5,7-Dimethylisatin,95%;5,7-Dimethylisatin,96%;5,7-dimethyl-indole-3-dione;5,7-dimethyl-indole-2,3-dione;5,7-DIMETHYL-2,3-INDOLINEDIONE
- CBNumber:
- CB1100167
- Molecular Formula:
- C10H9NO2
- Molecular Weight:
- 175.18
- MDL Number:
- MFCD00047219
- MOL File:
- 39603-24-2.mol
- MSDS File:
- SDS
| Melting point | 245 °C |
|---|---|
| Boiling point | 306.47°C (rough estimate) |
| Density | 1.250 |
| refractive index | 1.5060 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 10.43±0.20(Predicted) |
| Appearance | Yellow to orange Solid |
| Water Solubility | Insoluble in water. |
| BRN | 143679 |
| CAS DataBase Reference | 39603-24-2(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H319-H412 | |||||||||
| Precautionary statements | P273-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Safety Statements | 24/25-22 | |||||||||
| RTECS | NL7930000 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29337900 | |||||||||
| NFPA 704 |
|
5,7-Dimethylisatin price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR322609 | 5,7-Dimethylisatin >98% | 39603-24-2 | 5g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR322609 | 5,7-Dimethylisatin >98% | 39603-24-2 | 25g | $63 | 2026-06-04 | Buy |
| Apolloscientific | OR322609 | 5,7-Dimethylisatin >98% | 39603-24-2 | 100g | $245 | 2026-06-04 | Buy |
| Apolloscientific | OR322609 | 5,7-Dimethylisatin >98% | 39603-24-2 | 500g | $1204 | 2026-06-04 | Buy |
| Matrix Scientific | 030119 | 5,7-Dimethyl-1H-indole-2,3-dione | 39603-24-2 | 500.00mg | $126 | 2026-05-18 | Buy |
5,7-Dimethylisatin Chemical Properties, Uses, Production
Chemical Properties
red to red-brown powder
Uses
5,7-Dimethylisatin is used to produce cyano-(5,7-dimethyl-2-oxo-1,2-dihydro-indol-3-ylidene)-acetic acid ethyl ester by knoevenagel condensation with cyanoacetic acid ethyl ester. It is an important raw material and intermediate used in organic synthesis, pharmaceuticals and agrochemicals.
Synthesis
7343-12-6
39603-24-2
The general procedure for the synthesis of 5,7-dimethylindoline-2,3-dione using (E)-N-(2,4-dimethylphenyl)-2-(hydroxyimino)acetamide as starting material was as follows: concentrated sulfuric acid (20 mL) was added to a 100 mL flask with vigorous stirring at 50°C, and N-2-(hydroxyimino)acetamide derivatives (7.0 g) were added in batches. The reaction temperature was maintained between 50°C and 75°C, followed by the addition of sulfide. After the addition was completed, the reaction mixture was warmed to 80°C and stirring was continued for 30 minutes. After completion of the reaction, the mixture was cooled to room temperature and slowly poured into ice (250 g). The precipitated solid was collected and dried in air to give the crude product. The crude product was dissolved in 5% dilute sodium hydroxide solution (100 mL) and acidified with 4N hydrochloric acid (20 mL). The precipitated solid was filtered and dried thoroughly to give the purified target compound 5,7-dimethylindoline-2,3-dione.
References
[1] Journal of Chemical Research, Miniprint, 1998, # 7, p. 1425 - 1434
[2] Medicinal Chemistry, 2016, vol. 12, # 5, p. 489 - 498
[3] Journal of Organic Chemistry, 1952, vol. 17, p. 149,153
[4] Proceedings of the Royal Society of London, Series B: Biological Sciences, 1958, vol. 148, p. 481,488
[5] Gazzetta Chimica Italiana, 1955, vol. 85, p. 840,841
5,7-Dimethylisatin Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44566 | 61 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 15343 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10265 | 58 |
View Latest Price from 5,7-Dimethylisatin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-20 | 5,7-DIMETHYLISATIN
39603-24-2
|
$100.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2021-08-12 | 5,7-DIMETHYLISATIN
39603-24-2
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2019-12-25 | 5,7-DIMETHYLISATIN
39603-24-2
|
$1.00 | 1KG | 99% | 200kg | Career Henan Chemical Co |
-
- 5,7-DIMETHYLISATIN
39603-24-2
- $100.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 5,7-DIMETHYLISATIN
39603-24-2
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 5,7-DIMETHYLISATIN
39603-24-2
- $1.00
- 99%
- Career Henan Chemical Co
