Tectorigenin
- CAS No.
- 548-77-6
- Chemical Name:
- Tectorigenin
- Synonyms
- Tectrigenin;Tectorigenine;4',5,7-Trihydroxy-6-methoxyisoflavone;5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxychromone;5,7-Dihydroxy-3-(4-hydroxy-phenyl)-6-methoxy-chromen-4-one;5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one;6-Methoxy-5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one;5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-;Tectorigenin 5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one
- CBNumber:
- CB11040716
- Molecular Formula:
- C16H12O6
- Molecular Weight:
- 300.26
- MDL Number:
- MFCD00597094
- MOL File:
- 548-77-6.mol
- MSDS File:
- SDS
| Melting point | 225-226° |
|---|---|
| Boiling point | 361.5°C (rough estimate) |
| Density | 1.512 |
| refractive index | 1.4600 (estimate) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | DMSO : 150 mg/mL (499.57 mM; Need ultrasonic and warming) |
| form | powder to crystal |
| pka | 6.49±0.20(Predicted) |
| color | White to Orange to Green |
| BRN | 305601 |
| InChI | InChI=1S/C16H12O6/c1-21-16-11(18)6-12-13(15(16)20)14(19)10(7-22-12)8-2-4-9(17)5-3-8/h2-7,17-18,20H,1H3 |
| InChIKey | OBBCRPUNCUPUOS-UHFFFAOYSA-N |
| SMILES | C1OC2=CC(O)=C(OC)C(O)=C2C(=O)C=1C1=CC=C(O)C=C1 |
| CAS DataBase Reference | 548-77-6 |
| FDA UNII | 855130H9CO |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312-P330-P501 |
| WGK Germany | 3 |
| RTECS | NR2400000 |
| HS Code | 2932.99.6100 |
Tectorigenin price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | T3729 | Tectorigenin | 548-77-6 | 10MG | $138 | 2024-03-01 | Buy |
| TCI Chemical | T3729 | Tectorigenin | 548-77-6 | 50MG | $412 | 2024-03-01 | Buy |
| Biosynth Carbosynth | FT73920 | Tectorigenin | 548-77-6 | 100mg | $500 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | PXT0001061 | 4',5,7-TRIHYDROXY-6-METHOXYISOFLAVONE 95.00% | 548-77-6 | 5MG | $504.63 | 2021-12-16 | Buy |
| Matrix Scientific | 100270 | 5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one 95+% | 548-77-6 | 250mg | $742 | 2021-12-16 | Buy |
Tectorigenin Chemical Properties,Uses,Production
Description
Tectorigenin is an isoflavone that exists in numerous plant resources, and it is especially abundant in Belamcandae Rhizoma and Puerariae flos, which both have the effects of clearing away heat, removing toxic substances, relieving sore throat, and reducing swelling. As one of the most important active ingredients, the pharmacological effects of tectorigenin have been demonstrated by an increasing number of investigators. Due to its extensive pharmacological activities, including anticancer, antioxidation, hepatoprotection, anti-inflammation, etc., tectorigenin has received a large amount of attention[1].
Occurrence
Tectorigenin, a methoxy isoflavone with three hydroxyl groups, is chemically noted as 5,7-dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one. As a bioactive compound, tectorigenin is found in several plant species, most notably in the rhizomes of Belamcanda chinensis (L.) DC., a traditional Chinese medicine (TCM) named Belamcandae Rhizoma. The Iris family is the major source of tectorigenin, and many Iridaceous plants, such as Iris spuria L. (Calizona), Iris tectorum Maxim, Iris japonica Thunb., Iris dichotoma Pall., Iris germanica L., Iris unguicularis Poiret, Iris loczyi Kan., Iris kashmiriana Baker, Iris crocea Jacq. ex R. C. Foster, Iris ensata Thunb., Iris germanica L., Iris hungarica Waldst. et Kit., Iris confusa Sealy, and Iris pseudacorus L. contain abundant tectorigenin, so tectorigenin is also known as iris flavone. Tectorigenin also exists in some leguminous plants, such as the flowers of Pueraria lobata (Willd.) Ohwi, Pueraria thomsonii Benth., and Pueraria thunbergiana Benth. are also TCM called Puerariae Flos. Tectorigenin was isolated from the leaves of Dalbergia odorifera T. Chen, the heartwood of Dalbergia parviflora Roxb., and the roots of Euchresta formosana (Hayata) Ohwi as well. Moreover, some plants in other families also contain tectorigenin, including Codonopsis pilosula (Franch.) Nannf. (Campanulaceae), Morus alba L. (Moraceae), Viola hondoensis W. Becker et H. Boissieu. (Violaceae), and Eleocharis dulcis (Burm. f.) Trin. ex Hensch. (Cyperaceae)[1].
Uses
Tectorigenin is identified as an α-glucosidase inhibitors. Potent lactate dehydrogenase (LDH) inhibitor.
Definition
ChEBI: A methoxyisoflavone that is isoflavone substituted by a methoxy group at position 6 and hydroxy groups at positions 5, 7 and 4' respectively.
Synthesis Reference(s)
Synthetic Communications, 38, p. 525, 2008 DOI: 10.1080/00397910701796725
References
[1] Juan Rong. “Tectorigenin: A Review of Its Sources, Pharmacology, Toxicity, and Pharmacokinetics.” Molecules 28 15 (2023).
Tectorigenin Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3772 | 58 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29888 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | sales@dolonchem.com | CHINA | 2972 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 | info@konochemical.com | China | 2995 | 58 |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | sales@pioneerbiotech.com | China | 3000 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
View Lastest Price from Tectorigenin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-08-12 | Tectorigenin
548-77-6
|
US $220.00 / g | 1g | 98% HPLC | 50kg | Chengdu Biopurify Phytochemicals Ltd. | |
 |
2023-02-24 | Tectorigenin
548-77-6
|
US $0.00 / mg | 5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | |
 |
2019-07-06 | Tectorigenin
548-77-6
|
US $1.00 / kg | 1g | 99% | 100KG | Career Henan Chemical Co |
-
- Tectorigenin
548-77-6
- US $220.00 / g
- 98% HPLC
- Chengdu Biopurify Phytochemicals Ltd.
-
- Tectorigenin
548-77-6
- US $0.00 / mg
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
-
- Tectorigenin
548-77-6
- US $1.00 / kg
- 99%
- Career Henan Chemical Co