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Tectorigenin

CAS No.
548-77-6
Chemical Name:
Tectorigenin
Synonyms
Tectrigenin;Tectorigenine;4',5,7-Trihydroxy-6-methoxyisoflavone;5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxychromone;5,7-Dihydroxy-3-(4-hydroxy-phenyl)-6-methoxy-chromen-4-one;5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one;6-Methoxy-5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one;5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-;Tectorigenin 5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one
CBNumber:
CB11040716
Molecular Formula:
C16H12O6
Molecular Weight:
300.26
MDL Number:
MFCD00597094
MOL File:
548-77-6.mol
MSDS File:
SDS
Last updated:2024-08-14 10:54:21

Tectorigenin Properties

Melting point 225-226°
Boiling point 361.5°C (rough estimate)
Density 1.512
refractive index 1.4600 (estimate)
storage temp. Sealed in dry,2-8°C
solubility DMSO : 150 mg/mL (499.57 mM; Need ultrasonic and warming)
form powder to crystal
pka 6.49±0.20(Predicted)
color White to Orange to Green
BRN 305601
InChI InChI=1S/C16H12O6/c1-21-16-11(18)6-12-13(15(16)20)14(19)10(7-22-12)8-2-4-9(17)5-3-8/h2-7,17-18,20H,1H3
InChIKey OBBCRPUNCUPUOS-UHFFFAOYSA-N
SMILES C1OC2=CC(O)=C(OC)C(O)=C2C(=O)C=1C1=CC=C(O)C=C1
CAS DataBase Reference 548-77-6
FDA UNII 855130H9CO

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
WGK Germany  3
RTECS  NR2400000
HS Code  2932.99.6100

Tectorigenin price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical T3729 Tectorigenin 548-77-6 10MG $138 2024-03-01 Buy
TCI Chemical T3729 Tectorigenin 548-77-6 50MG $412 2024-03-01 Buy
Biosynth Carbosynth FT73920 Tectorigenin 548-77-6 100mg $500 2021-12-16 Buy
American Custom Chemicals Corporation PXT0001061 4',5,7-TRIHYDROXY-6-METHOXYISOFLAVONE 95.00% 548-77-6 5MG $504.63 2021-12-16 Buy
Matrix Scientific 100270 5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one 95+% 548-77-6 250mg $742 2021-12-16 Buy
Product number Packaging Price Buy
T3729 10MG $138 Buy
T3729 50MG $412 Buy
FT73920 100mg $500 Buy
PXT0001061 5MG $504.63 Buy
100270 250mg $742 Buy

Tectorigenin Chemical Properties,Uses,Production

Description

Tectorigenin is an isoflavone that exists in numerous plant resources, and it is especially abundant in Belamcandae Rhizoma and Puerariae flos, which both have the effects of clearing away heat, removing toxic substances, relieving sore throat, and reducing swelling. As one of the most important active ingredients, the pharmacological effects of tectorigenin have been demonstrated by an increasing number of investigators. Due to its extensive pharmacological activities, including anticancer, antioxidation, hepatoprotection, anti-inflammation, etc., tectorigenin has received a large amount of attention[1].

Occurrence

Tectorigenin, a methoxy isoflavone with three hydroxyl groups, is chemically noted as 5,7-dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one. As a bioactive compound, tectorigenin is found in several plant species, most notably in the rhizomes of Belamcanda chinensis (L.) DC., a traditional Chinese medicine (TCM) named Belamcandae Rhizoma. The Iris family is the major source of tectorigenin, and many Iridaceous plants, such as Iris spuria L. (Calizona), Iris tectorum Maxim, Iris japonica Thunb., Iris dichotoma Pall., Iris germanica L., Iris unguicularis Poiret, Iris loczyi Kan., Iris kashmiriana Baker, Iris crocea Jacq. ex R. C. Foster, Iris ensata Thunb., Iris germanica L., Iris hungarica Waldst. et Kit., Iris confusa Sealy, and Iris pseudacorus L. contain abundant tectorigenin, so tectorigenin is also known as iris flavone. Tectorigenin also exists in some leguminous plants, such as the flowers of Pueraria lobata (Willd.) Ohwi, Pueraria thomsonii Benth., and Pueraria thunbergiana Benth. are also TCM called Puerariae Flos. Tectorigenin was isolated from the leaves of Dalbergia odorifera T. Chen, the heartwood of Dalbergia parviflora Roxb., and the roots of Euchresta formosana (Hayata) Ohwi as well. Moreover, some plants in other families also contain tectorigenin, including Codonopsis pilosula (Franch.) Nannf. (Campanulaceae), Morus alba L. (Moraceae), Viola hondoensis W. Becker et H. Boissieu. (Violaceae), and Eleocharis dulcis (Burm. f.) Trin. ex Hensch. (Cyperaceae)[1].

Uses

Tectorigenin is identified as an α-glucosidase inhibitors. Potent lactate dehydrogenase (LDH) inhibitor.

Definition

ChEBI: A methoxyisoflavone that is isoflavone substituted by a methoxy group at position 6 and hydroxy groups at positions 5, 7 and 4' respectively.

Synthesis Reference(s)

Synthetic Communications, 38, p. 525, 2008 DOI: 10.1080/00397910701796725

References

[1] Juan Rong. “Tectorigenin: A Review of Its Sources, Pharmacology, Toxicity, and Pharmacokinetics.” Molecules 28 15 (2023).

Tectorigenin Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 172)Suppliers
Supplier Tel Email Country ProdList Advantage
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897 sales@biopurify.com China 3772 58
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3620 58
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29888 58
Chengdu GLP biotechnology Co Ltd
028-87075086 13350802083 scglp@glp-china.com CHINA 1824 58
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768 sales@dolonchem.com CHINA 2972 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Xi'an Kono chem co., Ltd.,
029-86107037 13289246953 info@konochemical.com China 2995 58
Shaanxi Pioneer Biotech Co., Ltd .
+8613259417953 sales@pioneerbiotech.com China 3000 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22968 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58

View Lastest Price from Tectorigenin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Tectorigenin pictures 2024-08-12 Tectorigenin
548-77-6
US $220.00 / g 1g 98% HPLC 50kg Chengdu Biopurify Phytochemicals Ltd.
Tectorigenin pictures 2023-02-24 Tectorigenin
548-77-6
US $0.00 / mg 5mg ≥98%(HPLC) 10 g Shanghai Standard Technology Co., Ltd.
Tectorigenin pictures 2019-07-06 Tectorigenin
548-77-6
US $1.00 / kg 1g 99% 100KG Career Henan Chemical Co
  • Tectorigenin pictures
  • Tectorigenin
    548-77-6
  • US $220.00 / g
  • 98% HPLC
  • Chengdu Biopurify Phytochemicals Ltd.
  • Tectorigenin pictures
  • Tectorigenin
    548-77-6
  • US $0.00 / mg
  • ≥98%(HPLC)
  • Shanghai Standard Technology Co., Ltd.
  • Tectorigenin pictures
  • Tectorigenin
    548-77-6
  • US $1.00 / kg
  • 99%
  • Career Henan Chemical Co

Tectorigenin Spectrum

Tectorigenin 5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one 5,7-Dihydroxy-3-(4-hydroxy-phenyl)-6-methoxy-chromen-4-one 5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one 6-Methoxy-5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one 5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one 4',5,7-Trihydroxy-6-methoxyisoflavone Tectorigenine Tectrigenin 4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-6-methoxy- 5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxychromone 548-77-6 chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract