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Tetrahydropalmatine

Description References
Tetrahydropalmatine
Tetrahydropalmatine
CAS No.
10097-84-4
Chemical Name:
Tetrahydropalmatine
Synonyms
Hyndarin;ROTUNDINE;Caseanine;Hindarine;Rutundine;ROTUNDINUM;AKOS 208-04;ROTUNDIN HYDRATE;Tetrahydropalmatin;TETRAHYDROPALMATINE
CBNumber:
CB1157651
Molecular Formula:
C21H25NO4
Formula Weight:
355.43
MOL File:
10097-84-4.mol

Tetrahydropalmatine Properties

CAS DataBase Reference
10097-84-4(CAS DataBase Reference)

SAFETY

Safety Statements  24/25
HS Code  29339900

Tetrahydropalmatine price

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Tetrahydropalmatine Chemical Properties,Uses,Production

Description

Tetrahydropalmatine (THP) is an isoquinoline alkaloid found in in several different plant species, mainly in the Corydalis genus (Yan Hu Suo), but also in other plants such as Stephania rotunda (Qian Jin Teng). These plants exhibits analgesic, antinociceptive, anxiolytic, antidepressant, and anti-parasitic activities, and have traditional uses in Chinese herbal medicine. In particular, the levo isomer of THP (l-THP) appears to contribute to many of the therapeutic effects of these herbs. Notably, the dextro isomer of THP has distinct pharmacological actions that include depletion of monoamines and may contribute to the toxicology profile of THP-containing preparations or racemic mixtures of the compound. In addition to serving as an active constituent in traditional Chinese herbal preparations, purified or synthetic l-THP is approved for use and available as Rotundine or Rotundin in China, where l-THP has been used as an analgesic and sedative for more than 40 years.

References

1. https://en.wikipedia.org/wiki/Tetrahydropalmatine
2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878639/
3.https://www.worldseedsupply.com/product/corydalis-yanhusuo-tetrahydropalmatine-98-pure-thp-isolate/
4. https://www.lktlabs.com/product/dl-tetrahydropalmatine/

Purification Methods

Crystallise it from MeOH or EtOH by addition of water [see Kametani & Ihara J Chem Soc (C) 530 1967, Bradsher & Dutta J Org Chem 26 2231 1961]. When crystallised from Me2CO/Et2O, it has m 142o. The hydrate has m 115o(effervescence). The picrate has m 188o(dec) (from aqueous EtOH). [Bradsher & Datta J Org Chem 26 2231 1961, Beilstein 21 II 196, 21 III/IV 2769.]

Tetrahydropalmatine Preparation Products And Raw materials

Raw materials

Preparation Products


Tetrahydropalmatine Suppliers

Global( 178)Suppliers
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Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3218 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32764 55
Kono Chem Co., Ltd
+86-132 8924 6953
info@konochemical.com CHINA 2164 58
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3624 58
Shaanxi Huike Botanical Development Co., Ltd +86-29-62663046;+86-18706899381
+86-29-82606529 market@huikes.com China 61 62
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、802、803、804 Mobile:18930552037
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JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078,021-50426030
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XiaoGan ShenYuan ChemPharm co,ltd Tell:86-712-2580635 Mobile:15527768850 . 15527768836
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10097-84-4(Tetrahydropalmatine)Related Search:


  • AKOS 208-04
  • 10097-84-4
  • L-TETRAHYDROPALMATINE
  • L-TETRAHYDROPALMATINE HCL
  • DL-TETRAHYDROPALMATINE
  • TETRAHYDROPALMATINE
  • ROTUNDINE
  • ROTUNDIN HYDRATE
  • ROTUNDINUM
  • 2,3,9,10-tetramethoxy-berbin
  • g)quinolizine,5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-6h-dibenzo(
  • Tetrahydropalmatin
  • Tetrahydropalmatine95+%
  • Alkaloids
  • Miscellaneous Natural Products
  • 5,8,13,13a-Tetrahydro-2,3,9,10-tetramethoxy-6H-dibenzo[a,g] quinolizine
  • 5,6,13,13a-Tetrahydro-2,3,9,10-tetramethoxy-8H-dibenzo[a,g]quinolizine
  • Hyndarin
  • (13aR)-2,3,9,10-Tetramethoxy-5,6,13,13a-tetrahydro-8H-dibenzo[a,g]quinolizine
  • (13aR)-5,8,13,13aβ-Tetrahydro-2,3,9,10-tetramethoxy-6H-dibenzo[a,g]quinolizine
  • Pharmaceutical intermediate
  • Rotundine/ L-TetrahydropalMatine
  • TetrahydropalMatine(Rotundine)
  • Caseanine
  • Hindarine
  • Plant extracts
  • chemical reagent
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • L-Tetrahydropalmatine, >=98%
  • Inhibitors
  • Rotundine, TETRAHYDROPALMATINE HYDROCHLORIDE
  • Rutundine
  • L-Tetrahydropalmatine hydrochloride, 98%, from Corydalis yanhusuo W. T. Wang ex Z. Y. Su & C. Y.
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