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N-HYDROXYPROPIONAMIDINE

N-HYDROXYPROPIONAMIDINE structure

CAS No.: 29335-36-2

Chemical Name:: N-HYDROXYPROPIONAMIDINE

Synonyms: Propionamidoxime;AKOS B030359;N-HYDROXYPROPIONAMIDINE;N'-hydroxypropaniMidaMide;N-HydroxypropioniMidaMide;(E)-N'-Hydroxypropimidamide;PropaniMidaMide, N-hydroxy-;(E)-N'-hydroxypropionimidamide;(1Z)-N'-hydroxypropanimidamide 1HCl;propanimidamide, N'-hydroxy-, (1Z)-

CBNumber:: CB1176256

Molecular Formula:: C3H8N2O

Molecular Weight:: 88.11

MDL Number:: MFCD03426272

MOL File:: 29335-36-2.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:45

Product description	Number	Pack Size	Price
(E)-N''-hydroxypropionimidamide	E555820	500mg	$265
N-Hydroxypropanimidamide hydrochloride	4147-5-06	1g	$184
(1Z)-N'-HYDROXYPROPANIMIDAMIDE	BP-21173	250mg	$35
N-Hydroxypropionamidine 97%	132104	1g	$396
(1Z)-N'-Hydroxypropanimidamidehydrochloride	9295AD	5g	$435

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N-HYDROXYPROPIONAMIDINE Properties

Boiling point	132.8±23.0 °C(Predicted)
Density	1.12±0.1 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
pka	7.48±0.69(Predicted)
Appearance	Colorless to off-white Viscous Liquid
Water Solubility	Slightly soluble in water.
Sensitive	Hygroscopic
CAS DataBase Reference	29335-36-2

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319

Precautionary statements

P280g-P305+P351+P338

Hazard Codes

Risk Statements

36/37/38-25

Safety Statements

26-36/37/39-45

RIDADR

UN3267

HazardClass

PackingGroup

III

HS Code

2925290090

NFPA 704

	1
2		1

N-HYDROXYPROPIONAMIDINE price More Price(20)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	E555820	(E)-N''-hydroxypropionimidamide	29335-36-2	500mg	$265	2021-12-16	Buy
SynQuest Laboratories	4147-5-06	N-Hydroxypropanimidamide hydrochloride	29335-36-2	1g	$184	2021-12-16	Buy
BroadPharm	BP-21173	(1Z)-N'-HYDROXYPROPANIMIDAMIDE	29335-36-2	250mg	$35	2021-12-16	Buy
Matrix Scientific	132104	N-Hydroxypropionamidine 97%	29335-36-2	1g	$396	2021-12-16	Buy
AK Scientific	9295AD	(1Z)-N'-Hydroxypropanimidamidehydrochloride	29335-36-2	5g	$435	2021-12-16	Buy

Product number	Packaging	Price	Buy
E555820	500mg	$265	Buy
4147-5-06	1g	$184	Buy
BP-21173	250mg	$35	Buy
132104	1g	$396	Buy
9295AD	5g	$435	Buy

N-HYDROXYPROPIONAMIDINE Chemical Properties,Uses,Production

Uses

Propionamidoxime is used as pharmaceutical intermediate.

Synthesis

107-12-0

29335-36-2

The general procedure for the synthesis of N-hydroxypropionic acid amidine from propionitrile was as follows: hydroxylamine hydrochloride (18.9 g, 272.7 mmol) and anhydrous potassium carbonate (37.6 g, 272.7 mmol) were suspended in a mixed solvent of ethanol/water (200 mL/50 mL), and stirred for 1 h at room temperature. Subsequently, propionitrile (10.0 g, 181.8 mmol) was added to the reaction system. The reaction mixture was heated to reflux and stirred continuously for 20 h. The reaction process was monitored by thin layer chromatography (unfolding agent: dichloromethane/methanol, 50/1 volume ratio). Upon completion of the reaction, the inorganic salts were removed by filtration and the filtrate was concentrated under reduced pressure to afford N-hydroxypropionic acid amidine (13.5 g, 81% yield) as a light yellow solid.

References

[1] Patent: CN104513235, 2017, B. Location in patent: Paragraph 1308; 1309
[2] Chemische Berichte, 1884, vol. 17, p. 2753
[3] Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1957, vol. 245, p. 419,420
[4] Comptes Rendus des Seances de l'Academie des Sciences, Serie C: Sciences Chimiques, 1966, vol. 262, p. 592 - 595
[5] Monatshefte fuer Chemie, 1982, vol. 113, p. 781 - 792

N-HYDROXYPROPIONAMIDINE Preparation Products And Raw materials

Raw materials

Propionitrile Potassium carbonate Water Ethanol Hydroxylamine hydrochloride

Preparation Products

Pyridine, 3-(3-ethyl-1,2,4-oxadiazol-5-yl)-1,2,5,6-tetrahydro- 5-(CHLOROMETHYL)-3-ETHYL-1,2,4-OXADIAZOLE

N-HYDROXYPROPIONAMIDINE Suppliers

Global( 87)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Speranza Chemical Co., Ltd.	+86-86-075521030354 +8618688942810	sophieliu@speranzachem.com	China	925	55
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5906	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29798	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17346	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
Hefei Hirisun Pharmatech Co., Ltd	+8615056975894	shawn@hirisunpharm.com	CHINA	9911	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52846	58
CR Corporation Limited	+8613062833949	fred.wen@crcorporation.cn	China	8645	58
GIHI CHEMICALS CO.,LIMITED	+8618058761490	info@gihichemicals.com	China	49944	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850	market18@leapchem.com	China	43339	58

Supplier	Advantage
Speranza Chemical Co., Ltd.	55
Shandong chuangyingchemical Co., Ltd.	58
career henan chemical co	58
SIMAGCHEM CORP	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Hefei Hirisun Pharmatech Co., Ltd	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
CR Corporation Limited	58
GIHI CHEMICALS CO.,LIMITED	58
HANGZHOU LEAP CHEM CO., LTD.	58

View Lastest Price from N-HYDROXYPROPIONAMIDINE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-01-13	N-HYDROXYPROPIONAMIDINE 29335-36-2	US $1.00 / KG	1g	99.0%	100kg	Career Henan Chemical Co

N-HYDROXYPROPIONAMIDINE
29335-36-2
US $1.00 / KG
99.0%
Career Henan Chemical Co

N-HYDROXYPROPIONAMIDINE Spectrum

N-HYDROXYPROPIONAMIDINE(29335-36-2)¹HNMR

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AKOS B030359 N-HYDROXYPROPIONAMIDINE (1Z)-N'-hydroxypropanimidamide hydrochloride propanimidamide, N'-hydroxy-, (1Z)- N'-hydroxypropaniMidaMide PropaniMidaMide, N-hydroxy- N-HydroxypropioniMidaMide (E)-N'-Hydroxypropimidamide (1Z)-N'-hydroxypropanimidamide(SALTDATA: HCl) (1Z)-N'-hydroxypropanimidamide 1HCl N-Hydroxypropanimidamide hydrochloride (E)-N'-hydroxypropionimidamide Propionamidoxime 29335-36-2 pharmacetical