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(R)-2-Phenyl-3-methylbutanoic acid

CAS No.
13491-13-9
Chemical Name:
(R)-2-Phenyl-3-methylbutanoic acid
Synonyms
(R)-3-Methyl-2-phenylbutanoic acid;(R)-2-Phenyl-3-methylbutanoic acid;[R,(-)]-3-Methyl-2-phenylbutyric acid;(aR)-alpha-(1-Methylethyl)-benzeneacetic acid;Benzeneacetic acid, α-(1-methylethyl)-, (αR)-;(alphaR)-alpha-(1-Methylethyl)benzeneacetic acid;Benzeneacetic acid, .alpha.-(1-methylethyl)-, (.alpha.R)-
CBNumber:
CB12191237
Molecular Formula:
C11H14O2
Molecular Weight:
178.23
MDL Number:
MFCD11505969
MOL File:
13491-13-9.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:45
Product description Number Pack Size Price
(R)-3-Methyl-2-phenylbutanoic Acid 97%EE AS29051 1g $201
(R)-3-Methyl-2-phenylbutanoic Acid 97%EE AS29051 5g $865
(R)-3-Methyl-2-phenylbutanoic acid 295259 250.00mg $54
(R)-3-Methyl-2-phenylbutanoic acid 295259 1.00g $137
(R)-3-Methyl-2-phenylbutanoic acid 295259 5.00g $674

(R)-2-Phenyl-3-methylbutanoic acid Properties

Density 1.063
storage temp. Sealed in dry,Room Temperature
Appearance White to off-white Solid

(R)-2-Phenyl-3-methylbutanoic acid price More Price(32)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS29051 (R)-3-Methyl-2-phenylbutanoic Acid 97%EE 13491-13-9 1g $201 2026-06-04 Buy
Activate Scientific AS29051 (R)-3-Methyl-2-phenylbutanoic Acid 97%EE 13491-13-9 5g $865 2026-06-04 Buy
Matrix Scientific 295259 (R)-3-Methyl-2-phenylbutanoic acid 13491-13-9 250.00mg $54 2026-05-19 Buy
Matrix Scientific 295259 (R)-3-Methyl-2-phenylbutanoic acid 13491-13-9 1.00g $137 2026-05-19 Buy
Matrix Scientific 295259 (R)-3-Methyl-2-phenylbutanoic acid 13491-13-9 5.00g $674 2026-05-19 Buy
Product number Packaging Price Buy
AS29051 1g $201 Buy
AS29051 5g $865 Buy
295259 250.00mg $54 Buy
295259 1.00g $137 Buy
295259 5.00g $674 Buy

(R)-2-Phenyl-3-methylbutanoic acid Chemical Properties,Uses,Production

Synthesis

2-Isopropyl-2-phenylacetic acid

3508-94-9

(R)-2-Phenyl-3-methylbutanoic acid

13491-13-9

General procedure for the synthesis of (R)-3-methyl-2-phenylbutyric acid from 3-methyl-2-phenylbutyric acid: 2-isopropylphenylacetic acid (8.91 g), (+)-α-phenylethylamine (6.45 mL), and 63% aqueous ethanol (193 mL) were mixed, and the reaction was slowed and cooled by reflux. The resulting salt was purified by three recrystallizations from 63% aqueous ethanol solution. Subsequently, the salt was treated with 10% sulfuric acid at 0 °C, the reaction mixture was extracted with ethyl acetate, and the organic phase was dried and concentrated to give 3.52 g of (R)-(-)-2-isopropylphenylacetic acid in 39% yield, [α]25D -58.6° (CHCl3, c = 0.02).

References

[1] European Journal of Medicinal Chemistry, 2017, vol. 140, p. 42 - 51
[2] Chemical Communications, 2006, # 34, p. 3600 - 3602

(R)-2-Phenyl-3-methylbutanoic acid Preparation Products And Raw materials

(R)-2-Phenyl-3-methylbutanoic acid Suppliers

Global( 52)Suppliers
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Accela ChemBio Inc.
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Alchem Pharmtech,Inc.
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CONIER CHEM AND PHARMA LIMITED
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Aladdin Scientific
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DAYANG CHEM (HANGZHOU) CO.,LTD
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Amadis Chemical Company Limited
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NovoChemy Ltd. -- sales@novochemy.com Germany 6324 58
SynAsst Chemical. 021-60343070 China 12731 55
Shanghai Sheepchem Co., Ltd. +86 (21) 6715-7650 sheepchem@163.com China 993 60
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60

(R)-2-Phenyl-3-methylbutanoic acid Spectrum

(R)-2-Phenyl-3-methylbutanoic acid [R,(-)]-3-Methyl-2-phenylbutyric acid (alphaR)-alpha-(1-Methylethyl)benzeneacetic acid Benzeneacetic acid, .alpha.-(1-methylethyl)-, (.alpha.R)- (R)-3-Methyl-2-phenylbutanoic acid Benzeneacetic acid, α-(1-methylethyl)-, (αR)- (aR)-alpha-(1-Methylethyl)-benzeneacetic acid 13491-13-9