(R)-2-Phenyl-3-methylbutanoic acid
- CAS No.
- 13491-13-9
- Chemical Name:
- (R)-2-Phenyl-3-methylbutanoic acid
- Synonyms
- (R)-3-Methyl-2-phenylbutanoic acid;(R)-2-Phenyl-3-methylbutanoic acid;[R,(-)]-3-Methyl-2-phenylbutyric acid;(aR)-alpha-(1-Methylethyl)-benzeneacetic acid;Benzeneacetic acid, α-(1-methylethyl)-, (αR)-;(alphaR)-alpha-(1-Methylethyl)benzeneacetic acid;Benzeneacetic acid, .alpha.-(1-methylethyl)-, (.alpha.R)-
- CBNumber:
- CB12191237
- Molecular Formula:
- C11H14O2
- Molecular Weight:
- 178.23
- MDL Number:
- MFCD11505969
- MOL File:
- 13491-13-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| (R)-3-Methyl-2-phenylbutanoic Acid 97%EE | AS29051 | 1g | $201 |
| (R)-3-Methyl-2-phenylbutanoic Acid 97%EE | AS29051 | 5g | $865 |
| (R)-3-Methyl-2-phenylbutanoic acid | 295259 | 250.00mg | $54 |
| (R)-3-Methyl-2-phenylbutanoic acid | 295259 | 1.00g | $137 |
| (R)-3-Methyl-2-phenylbutanoic acid | 295259 | 5.00g | $674 |
(R)-2-Phenyl-3-methylbutanoic acid price More Price(32)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS29051 | (R)-3-Methyl-2-phenylbutanoic Acid 97%EE | 13491-13-9 | 1g | $201 | 2026-06-04 | Buy |
| Activate Scientific | AS29051 | (R)-3-Methyl-2-phenylbutanoic Acid 97%EE | 13491-13-9 | 5g | $865 | 2026-06-04 | Buy |
| Matrix Scientific | 295259 | (R)-3-Methyl-2-phenylbutanoic acid | 13491-13-9 | 250.00mg | $54 | 2026-05-19 | Buy |
| Matrix Scientific | 295259 | (R)-3-Methyl-2-phenylbutanoic acid | 13491-13-9 | 1.00g | $137 | 2026-05-19 | Buy |
| Matrix Scientific | 295259 | (R)-3-Methyl-2-phenylbutanoic acid | 13491-13-9 | 5.00g | $674 | 2026-05-19 | Buy |
(R)-2-Phenyl-3-methylbutanoic acid Chemical Properties,Uses,Production
Synthesis
3508-94-9
13491-13-9
General procedure for the synthesis of (R)-3-methyl-2-phenylbutyric acid from 3-methyl-2-phenylbutyric acid: 2-isopropylphenylacetic acid (8.91 g), (+)-α-phenylethylamine (6.45 mL), and 63% aqueous ethanol (193 mL) were mixed, and the reaction was slowed and cooled by reflux. The resulting salt was purified by three recrystallizations from 63% aqueous ethanol solution. Subsequently, the salt was treated with 10% sulfuric acid at 0 °C, the reaction mixture was extracted with ethyl acetate, and the organic phase was dried and concentrated to give 3.52 g of (R)-(-)-2-isopropylphenylacetic acid in 39% yield, [α]25D -58.6° (CHCl3, c = 0.02).
References
[1] European Journal of Medicinal Chemistry, 2017, vol. 140, p. 42 - 51
[2] Chemical Communications, 2006, # 34, p. 3600 - 3602
(R)-2-Phenyl-3-methylbutanoic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
(R)-2-Phenyl-3-methylbutanoic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Accela ChemBio Inc. | +1-858-6993322 +86-18019713315 | info@accelachem.com | United States | 21189 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57473 | 58 | |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53799 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| NovoChemy Ltd. | -- | sales@novochemy.com | Germany | 6324 | 58 |
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
| Shanghai Sheepchem Co., Ltd. | +86 (21) 6715-7650 | sheepchem@163.com | China | 993 | 60 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Supplier | Advantage |
|---|---|
| Accela ChemBio Inc. | 58 |
| Alchem Pharmtech,Inc. | 58 |
| CONIER CHEM AND PHARMA LIMITED | 58 |
| Aladdin Scientific | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | 58 |
| Amadis Chemical Company Limited | 58 |
| NovoChemy Ltd. | 58 |
| SynAsst Chemical. | 55 |
| Shanghai Sheepchem Co., Ltd. | 60 |
| Bide Pharmatech Ltd. | 60 |




