(R)-2-Phenyl-3-methylbutanoic acid
- CAS No.
- 13491-13-9
- Chemical Name:
- (R)-2-Phenyl-3-methylbutanoic acid
- Synonyms
- (R)-3-Methyl-2-phenylbutanoic acid;(R)-2-Phenyl-3-methylbutanoic acid;[R,(-)]-3-Methyl-2-phenylbutyric acid;(aR)-alpha-(1-Methylethyl)-benzeneacetic acid;Benzeneacetic acid, α-(1-methylethyl)-, (αR)-;(alphaR)-alpha-(1-Methylethyl)benzeneacetic acid;Benzeneacetic acid, .alpha.-(1-methylethyl)-, (.alpha.R)-
- CBNumber:
- CB12191237
- Molecular Formula:
- C11H14O2
- Molecular Weight:
- 178.23
- MDL Number:
- MFCD11505969
- MOL File:
- 13491-13-9.mol
- MSDS File:
- SDS
(R)-2-Phenyl-3-methylbutanoic acid price More Price(32)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS29051 | (R)-3-Methyl-2-phenylbutanoic Acid 97%EE | 13491-13-9 | 1g | $201 | 2026-06-04 | Buy |
| Activate Scientific | AS29051 | (R)-3-Methyl-2-phenylbutanoic Acid 97%EE | 13491-13-9 | 5g | $865 | 2026-06-04 | Buy |
| Matrix Scientific | 295259 | (R)-3-Methyl-2-phenylbutanoic acid | 13491-13-9 | 250.00mg | $54 | 2026-05-19 | Buy |
| Matrix Scientific | 295259 | (R)-3-Methyl-2-phenylbutanoic acid | 13491-13-9 | 1.00g | $137 | 2026-05-19 | Buy |
| Matrix Scientific | 295259 | (R)-3-Methyl-2-phenylbutanoic acid | 13491-13-9 | 5.00g | $674 | 2026-05-19 | Buy |
(R)-2-Phenyl-3-methylbutanoic acid Chemical Properties, Uses, Production
Synthesis
3508-94-9
13491-13-9
General procedure for the synthesis of (R)-3-methyl-2-phenylbutyric acid from 3-methyl-2-phenylbutyric acid: 2-isopropylphenylacetic acid (8.91 g), (+)-α-phenylethylamine (6.45 mL), and 63% aqueous ethanol (193 mL) were mixed, and the reaction was slowed and cooled by reflux. The resulting salt was purified by three recrystallizations from 63% aqueous ethanol solution. Subsequently, the salt was treated with 10% sulfuric acid at 0 °C, the reaction mixture was extracted with ethyl acetate, and the organic phase was dried and concentrated to give 3.52 g of (R)-(-)-2-isopropylphenylacetic acid in 39% yield, [α]25D -58.6° (CHCl3, c = 0.02).
References
[1] European Journal of Medicinal Chemistry, 2017, vol. 140, p. 42 - 51
[2] Chemical Communications, 2006, # 34, p. 3600 - 3602
(R)-2-Phenyl-3-methylbutanoic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
(R)-2-Phenyl-3-methylbutanoic acid Suppliers
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| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
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