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OXOMEMAZINE

OXOMEMAZINE structure

CAS No.: 3689-50-7

Chemical Name:: OXOMEMAZINE

Synonyms: Imakol;6847 RP;6487 RP;Dysedon;RP-6847;Doxergan;Dosegran;6847 R.P.;Oxomemazin;OXOEMAZINE

CBNumber:: CB1236273

Molecular Formula:: C18H22N2O2S

Molecular Weight:: 330.44

MDL Number:: MFCD00868197

MOL File:: 3689-50-7.mol

MSDS File:: SDS

Last updated:2023-05-21 10:59:17

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OXOMEMAZINE Properties

Melting point	115°
Boiling point	492.4±34.0 °C(Predicted)
Density	1.1453 (rough estimate)
refractive index	1.6000 (estimate)
storage temp.	Store at -20°C
solubility	≥ 33mg/mL in DMSO
pka	9.31±0.28(Predicted)
FDA UNII	305MB38V1C
ATC code	R06AD08

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS06
Signal word	Danger
Hazard statements	H330-H311-H301
Precautionary statements	P260-P271-P284-P304+P340-P310-P320-P403+P233-P405-P501-P264-P270-P301+P310-P321-P330-P405-P501-P280-P302+P352-P312-P322-P361-P363-P405-P501
Toxicity	LD50 oral in mouse: 140mg/kg

OXOMEMAZINE price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	O860005	(±)-Oxomemazine	3689-50-7	1g	$920	2021-12-16	Buy
American Custom Chemicals Corporation	API0009875	OXOMEMAZINE 95.00%	3689-50-7	1G	$892.5	2021-12-16	Buy
ChemScene	CS-0131898	Oxomemazine	3689-50-7	10mg	$60	2021-12-16	Buy
American Custom Chemicals Corporation	API0009875	OXOMEMAZINE 95.00%	3689-50-7	5MG	$502.11	2021-12-16	Buy
Crysdot	CD11134460	Oxomemazine 97%	3689-50-7	1g	$680	2021-12-16	Buy

Product number	Packaging	Price	Buy
O860005	1g	$920	Buy
API0009875	1G	$892.5	Buy
CS-0131898	10mg	$60	Buy
API0009875	5MG	$502.11	Buy
CD11134460	1g	$680	Buy

OXOMEMAZINE Chemical Properties,Uses,Production

Originator

Doxergan,Specia,France,1964

Uses

(±)-Oxomemazine, is a phenothiazine-type antihistamines, that has also shown antibacterial activity against Mycobacterium tuberculosis.

Definition

ChEBI: Oxomemazine is a member of phenothiazines.

Manufacturing Process

Phenothiazine is reacted with 3-dimethylamino-2-methylpropyl chloride in the presence of sodium amide to give 3-(10-phenthiazinyl)-2-methyl-1dimethylaminopropane. 11.9 g of of this intermediate is dissolved with agitation in glacial acetic acid (120 cc). Pure sulfuric acid (d = 1.83; 0.5 cc) is added and a mixture of glacial acetic acid (10 cc) and hydrogen peroxide (8.5 cc of a solution containing 38 g of hydrogen peroxide in 100 cc) is then run in over 20 minutes. The temperature rises from 25°C to 35°C and is then kept at 60°C for 18 hours. The mixture is cooled and water (150 cc) is added and, with cooling, aqueous sodium hydroxide (d = 1.33; 220 cc). The resulting mixture is extracted with ethyl acetate (3 x 100 cc), the solvent is evaporated on a water bath and the residue is recrystallized from heptane (150 cc). 3(9,9-dioxy-10-phenthiazinyl)-2-methyl-1-dimethylaminopropane (78 g) is obtained, MP 115°C.
The corresponding hydrochloride prepared in ethyl acetate and recrystallized from a mixture of ethanol and isopropanol melts at 250°C.

Therapeutic Function

Antihistaminic

OXOMEMAZINE Preparation Products And Raw materials

Raw materials

Sodium amide 3-DIMETHYLAMINO-2-METHYLPROPYL CHLORIDE Hydrogen peroxide Phenothiazine

Preparation Products

OXOMEMAZINE Suppliers

Global( 54)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shijiazhuang Gantuo Biotechnology Co., Ltd	+8613373514458	gantuo02@cngantuo.com	China	218	58
AFINE CHEMICALS LIMITED	0571-85134551	info@afinechem.com	CHINA	15377	58
Dayang Chem (Hangzhou) Co.,Ltd.	571-88938639 +8617705817739	info@dycnchem.com	CHINA	52867	58
Alfa Chemistry	+1-5166625404	Info@alfa-chemistry.com	United States	21317	58
Shaanxi Didu New Materials Co. Ltd	+86-89586680 +86-13289823923	1026@dideu.com	China	9116	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
GIHI CHEMICALS CO.,LIMITED	+8618058761490	info@gihichemicals.com	China	50000	58
Hebei Miaoyin Technology Co.,Ltd	+86-17367732028 +86-17367732028	kathy@hbyinsheng.com	China	3582	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58

Supplier	Advantage
Shijiazhuang Gantuo Biotechnology Co., Ltd	58
AFINE CHEMICALS LIMITED	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Alfa Chemistry	58
Shaanxi Didu New Materials Co. Ltd	58
TargetMol Chemicals Inc.	58
GIHI CHEMICALS CO.,LIMITED	58
Hebei Miaoyin Technology Co.,Ltd	58
LEAPCHEM CO., LTD.	58
Aladdin Scientific	58

View Lastest Price from OXOMEMAZINE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2023-06-26	Oxomemazine 3689-50-7	US $200.00 / kg	1kg	99%	1000kg/Month	Hebei Mingeng Biotechnology Co., Ltd
	2023-04-11	Oxomemazine 3689-50-7	US $100.00 / g	10g	99%	1000g	Shijiazhuang Gantuo Biotechnology Co., Ltd

Oxomemazine
3689-50-7
US $200.00 / kg
99%
Hebei Mingeng Biotechnology Co., Ltd

Oxomemazine
3689-50-7
US $100.00 / g
99%
Shijiazhuang Gantuo Biotechnology Co., Ltd

OXOMEMAZINE Spectrum

OXOMEMAZINE(3689-50-7)¹HNMR

3689-50-7(OXOMEMAZINE)Related Search:

Piperacillin Hydrochlorothiazide Phenothiazine TRIMEPRAZINE SULPHONE N-OXIDE HYDROCHLORIDE (OXOMEMAZINE N-OXIDE HYDROCHLORIDE) OXOMEMAZINE HCL

Oxomemazine hydrochloride,Oxomemazine·hydrochloric acid OXOMEMAZINE N-OXIDE HYDROCHLORIDE(TRIMEPRAZINE SULPHONE N-OXIDE HYDROCHLORIDE) OXOMEMAZINE BASE& HCL TRIMEPRAZINE SULPHONE (OXOMEMAZINE) OXOMEMAZINE

Trimeprazine 2-(Phenylsulfonyl)aniline PHENOTHIAZINE-5-OXIDE

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OXOMEMAZINE 10-(3-(Dimethylamino)-2-methylpropyl)phenothiazine-5,5-dioxide 10H-Phenothiazine-10-propanamine, N,N,beta-trimethyl-, 5,5-dioxide 3-(5,5-Dioxido-10H-phenothiazin-10-yl)-N,N,2-trimethyl-1-propanamine 6487 RP 6847 R.P. 6847 RP Alimemazine S,S-dioxide Dosegran Doxergan Dysedon Imakol Oxomemazin Oxymemazine Phenothiazine, 10-[3-(dimethylamino)-2-methylpropyl]-, 5,5-dioxide RP-6847 S,S-Dioxo-9,9-(dimethylamino-3-methyl-2-propyl)-10-phenothiazine Trimeprazine 5,5-dioxide Oxomemazinebase Oxomenazine OXOEMAZINE 10-(3-Dimethylamino-2-methylpropyl)-10H-phenothiazine 5,5-dioxide 10-[2-(Dimethylaminomethyl)propyl]-10H-phenothiazine 5,5-dioxide N,N,β-Trimethyl-10H-phenothiazine-10-propan-1-amine 5,5-dioxide [3-(5,5-diketophenothiazin-10-yl)-2-methyl-propyl]-dimethyl-amine 3-(5,5-dioxophenothiazin-10-yl)-N,N,2-trimethyl-propan-1-amine 3-(5,5-dioxophenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine 10H-Phenothiazine-10-propanamine, N,N,β-trimethyl-, 5,5-dioxide OxomemazineQ: What is Oxomemazine Q: What is the CAS Number of Oxomemazine Q: What is the storage condition of Oxomemazine Q: What are the applications of Oxomemazine histamine H1-receptor,OXOMEMAZINE,Histamine Receptor,inhibit,phenothiazine,antimuscarinic,muscarinic M1,Inhibitor,Metabotropic glutamate receptors,cough,anticholinergic,antihistamine,mGluR 3689-50-7