2,4,5-Trifluorobenzoic acid
- CAS No.
- 446-17-3
- Chemical Name:
- 2,4,5-Trifluorobenzoic acid
- Synonyms
- 2,4,5-Trilfuorobenzoic acid;2,4,5-TrifL;RARECHEM AL BO 0258;2,4,5-Trifluorobenzo;5-Trifluorobenzoic acid;2,4,5-tifluorobenzoicacid;2,4,5-TRIFLUOROBENZOIC ACID;Benzoic acid, 2,4,5-trifluoro-;2,4,5-Trifluorobenzoic acid 99%;2,4,5-Trifluorobenzoic acid ,99%
- CBNumber:
- CB1742985
- Molecular Formula:
- C7H3F3O2
- Molecular Weight:
- 176.09
- MDL Number:
- MFCD00013306
- MOL File:
- 446-17-3.mol
- MSDS File:
- SDS
Melting point | 94-96 °C (lit.) |
---|---|
Boiling point | 241.9±35.0 °C(Predicted) |
Density | 1.4362 (estimate) |
storage temp. | Sealed in dry,Room Temperature |
solubility | Chloroform (Slightly), DMSO (Slightly) |
form | Solid |
pka | 2.87±0.10(Predicted) |
color | Off-White |
BRN | 3257609 |
InChIKey | AKAMNXFLKYKFOJ-UHFFFAOYSA-N |
CAS DataBase Reference | 446-17-3(CAS DataBase Reference) |
EPA Substance Registry System | Benzoic acid, 2,4,5-trifluoro- (446-17-3) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319 | |||||||||
Precautionary statements | P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26-36-24/25 | |||||||||
WGK Germany | 3 | |||||||||
HazardClass | IRRITANT | |||||||||
HS Code | 29163990 | |||||||||
NFPA 704 |
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2,4,5-Trifluorobenzoic acid price More Price(34)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 328154 | 2,4,5-Trifluorobenzoic acid 99% | 446-17-3 | 5g | $25.62 | 2024-03-01 | Buy |
TCI Chemical | T1586 | 2,4,5-Trifluorobenzoic Acid >97.0%(GC)(T) | 446-17-3 | 5g | $54 | 2024-03-01 | Buy |
TCI Chemical | T1586 | 2,4,5-Trifluorobenzoic Acid >97.0%(GC)(T) | 446-17-3 | 25g | $216 | 2024-03-01 | Buy |
Alfa Aesar | A14193 | 2,4,5-Trifluorobenzoic acid, 98% | 446-17-3 | 5g | $94.65 | 2024-03-01 | Buy |
Alfa Aesar | A14193 | 2,4,5-Trifluorobenzoic acid, 98% | 446-17-3 | 1g | $30.5 | 2021-12-16 | Buy |
2,4,5-Trifluorobenzoic acid Chemical Properties,Uses,Production
Chemical Properties
white to light yellow crystal powder
Uses
2,4,5-Trifluorobenzoic Acid is a useful synthetic intermediate. It can be used to synthesize quinolone antibacterial agnts.
Preparation
Synthesis of 2,4,5-trifluorobenzoic acid: Tetrachloroisophthalonitrile was used as the starting material, which was fluoridated, selectively reduced, and partially defluoridated to obtain 2,4,5-trifluoroisophthalonitrile. This compound was hydrolyzed to form 2,4,5-trifluoroisophthalic acid. Then, selective decarboxylation of 2,4,5-trifluorobenzoic acid was carried out to prepare 2,4,5-trifluorobenzoic acid.
Synthesis Reference(s)
Journal of Medicinal Chemistry, 34, p. 168, 1991 DOI: 10.1021/jm00105a025
General Description
2,4,5-Trifluorobenzoic acid is an important quinolone antibacterial intermediate. It is used in the synthesis of Temafloxacin and liquid crystals, among others.
2,4,5-Trifluorobenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12470 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 18223 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15956 | 58 |
Hi-Tech Chemistry Corp | 0519-86626038 | yuhh@hitechem.com | CHINA | 811 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21689 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9341 | 55 |
Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
Fluoropharm Co., Ltd. | +86-0571-85586753; +8613336034509 | sales@fluoropharm.com | China | 1377 | 60 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
View Lastest Price from 2,4,5-Trifluorobenzoic acid manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-05-24 | 2,4,5-trifluorobenzoic acid
446-17-3
|
US $20.00 / KG | 1KG | 98% | 446-17-3 | Speranza Chemical Co., Ltd. | ||
2024-04-20 | 2,4,5-Trifluorobenzoic acid
446-17-3
|
US $35.00-1.10 / kg | 1kg | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | ||
2023-09-06 | 2,4,5-Trifluorobenzoic acid
446-17-3
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd |
- 2,4,5-trifluorobenzoic acid
446-17-3
- US $20.00 / KG
- 98%
- Speranza Chemical Co., Ltd.
- 2,4,5-Trifluorobenzoic acid
446-17-3
- US $35.00-1.10 / kg
- 99%
- Henan Fengda Chemical Co., Ltd
- 2,4,5-Trifluorobenzoic acid
446-17-3
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
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