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4-Fluorobenzoic acid

Description Reference
4-Fluorobenzoic acid
4-Fluorobenzoic acid
Chemical Name:
4-Fluorobenzoic acid
PFBA;The acid;AKOS 92636;p-Fluorobenzoic;fluorobenzoicacid;Fluoro benzoic ac;4-fluoro-benzoicaci;RARECHEM AL BO 0053;TIMTEC-BB SBB008568;4-Fluorobenzoi acid
Molecular Formula:
Formula Weight:
MOL File:

4-Fluorobenzoic acid Properties

Melting point:
184 °C
storage temp. 
Store below +30°C.
alcohol: soluble
Crystalline Powder
4.15(at 25℃)
White to slightly yellow
Water Solubility 
Soluble in alcohol, hot water, methanol, and ether. Very slightly soluble in cold water.
CAS DataBase Reference
456-22-4(CAS DataBase Reference)
NIST Chemistry Reference
Benzoic acid, 4-fluoro-(456-22-4)
EPA Substance Registry System
Benzoic acid, 4-fluoro-(456-22-4)
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xn,Xi
Risk Statements  22-41-36/37/38
Safety Statements  26-39-24/25-22-37/39-36
WGK Germany  3
Hazard Note  Irritant
HazardClass  IRRITANT
HS Code  29163900
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger P280, P305+P351+P338, P310
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

4-Fluorobenzoic acid price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 128384 4-Fluorobenzoic acid 98% 456-22-4 5g $13.5 2018-11-13 Buy
Sigma-Aldrich 128384 4-Fluorobenzoic acid 98% 456-22-4 25g $28.2 2018-11-13 Buy
TCI Chemical F0112 4-Fluorobenzoic Acid >98.0%(GC)(T) 456-22-4 25g $48 2018-11-22 Buy
Alfa Aesar A14129 4-Fluorobenzoic acid, 98% 456-22-4 25g $26.2 2018-11-13 Buy
Alfa Aesar A14129 4-Fluorobenzoic acid, 98% 456-22-4 100g $67.9 2018-11-13 Buy

4-Fluorobenzoic acid Chemical Properties,Uses,Production


4-Fluorobenzoic acid is used as an intermediate in organic synthesis. For instance, it is used to synthesize N-cuccinimidyl 4-[18F]-fluorobenzoate, which is used for the 18F labeling of antibodies. It has been used in high resolution charge density study.


AG. Vaidyanathan, M. R. Zalutsky, Improved Synthesis of N-Succinimidyl 4-[18F]Fluorobenzoate and Its Application to the Labeling of a Monoclonal Antibody Fragment, Bioconjuate Chemistry, 1994, vol. 5, pp. 352-356

Chemical Properties

white to light yellow crystal powder


ChEBI: A fluorobenzoic acid carrying a fluoro substituent at position 4.

Purification Methods

Crystallise the acid from 50% aqueous EtOH, then purify it by zone melting or vacuum sublimation at 130-140o. [Beilstein 9 H 333, 9 III 1327, 9 IV 953.]

4-Fluorobenzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

4-Fluorobenzoic acid Suppliers

Global( 348)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-55531817 CHINA 22059 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693 CHINA 20795 55
Mainchem Co., Ltd.
+86-0592-6210733 CHINA 32764 55
Speranza Chemical Co., Ltd.
+86-755-33122716 CHINA 171 55
career henan chemical co
+86-371-86658258 CHINA 20001 58
Shanghai JONLN Reagent Co., Ltd. 400-0066-400;021-60496031
021-55660885 China 10295 55
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933; China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)
+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing) China 40399 62
Alfa Aesar 400-610-6006; 021-67582000
021-67582001/03/05 China 30308 84
Danyang Wanlong Chemical Co., Ltd 0511-86810888 0511-86810995 0511-86810993
0511-86810666 China 65 55

View Lastest Price from 4-Fluorobenzoic acid manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-21 4-Fluorobenzoic acid
US $1.00 / kg 1g 99% 100KG career henan chemical co

4-Fluorobenzoic acid Spectrum

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