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4-Fluorobenzoic acid

Description Reference
4-Fluorobenzoic acid
4-Fluorobenzoic acid structure
CAS No.
456-22-4
Chemical Name:
4-Fluorobenzoic acid
Synonyms
PFBA;The acid;AKOS 92636;p-Fluorobenzoic;fluorobenzoicacid;Fluoro benzoic ac;4-Fluorbenzoesure;4-Fluorobenzoi acid;4-fluoro-benzoicaci;TIMTEC-BB SBB008568
CBNumber:
CB4853637
Molecular Formula:
C7H5FO2
Formula Weight:
140.11
MOL File:
456-22-4.mol

4-Fluorobenzoic acid Properties

Melting point:
182-184 °C (lit.)
Boiling point:
117 °C
Density 
1.479
storage temp. 
Sealed in dry,Room Temperature
solubility 
alcohol: soluble
form 
Crystalline Powder
pka
4.15(at 25℃)
color 
White to slightly yellow
Water Solubility 
Soluble in alcohol, hot water, methanol, and ether. Very slightly soluble in cold water.
Merck 
14,4171
BRN 
1906922
InChIKey
BBYDXOIZLAWGSL-UHFFFAOYSA-N
CAS DataBase Reference
456-22-4(CAS DataBase Reference)
FDA UNII
V5ROO2HOU4
NIST Chemistry Reference
Benzoic acid, 4-fluoro-(456-22-4)
EPA Substance Registry System
Benzoic acid, 4-fluoro- (456-22-4)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS05,GHS07
Signal word  Danger
Hazard statements  H315-H319-H335-H302-H318
Precautionary statements  P280-P305+P351+P338-P261-P280a-P304+P340-P405-P501a
Hazard Codes  Xn,Xi
Risk Statements  22-41-36/37/38
Safety Statements  26-39-24/25-22-37/39-36
WGK Germany  3
Hazard Note  Irritant
TSCA  T
HazardClass  IRRITANT
HS Code  29163900

4-Fluorobenzoic acid price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 128384 4-Fluorobenzoic acid 98% 456-22-4 5g $14.7 2021-03-22 Buy
Sigma-Aldrich 128384 4-Fluorobenzoic acid 98% 456-22-4 25g $29.9 2021-03-22 Buy
TCI Chemical F0112 4-Fluorobenzoic Acid >98.0%(GC)(T) 456-22-4 25g $51 2021-03-22 Buy
Alfa Aesar A14129 4-Fluorobenzoic acid, 98% 456-22-4 25g $27.8 2020-06-24 Buy
Alfa Aesar A14129 4-Fluorobenzoic acid, 98% 456-22-4 100g $71.6 2020-06-24 Buy

4-Fluorobenzoic acid Chemical Properties,Uses,Production

Description

4-Fluorobenzoic acid is used as an intermediate in organic synthesis. For instance, it is used to synthesize N-cuccinimidyl 4-[18F]-fluorobenzoate, which is used for the 18F labeling of antibodies. It has been used in high resolution charge density study.

Reference

AG. Vaidyanathan, M. R. Zalutsky, Improved Synthesis of N-Succinimidyl 4-[18F]Fluorobenzoate and Its Application to the Labeling of a Monoclonal Antibody Fragment, Bioconjuate Chemistry, 1994, vol. 5, pp. 352-356

Chemical Properties

white to light yellow crystal powder

Definition

ChEBI: A fluorobenzoic acid carrying a fluoro substituent at position 4.

Purification Methods

Crystallise the acid from 50% aqueous EtOH, then purify it by zone melting or vacuum sublimation at 130-140o. [Beilstein 9 H 333, 9 III 1327, 9 IV 953.]

4-Fluorobenzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products


4-Fluorobenzoic acid Suppliers

Global( 434)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Speranza Chemical Co., Ltd.
+8618688942810
+86-755-33122716 sophieliu@speranzachem.com CHINA 279 55
Henan DaKen Chemical CO.,LTD.
+86-371-66670886
info@dakenchem.com China 21031 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22607 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 29960 58
Accela ChemBio Inc.
(+1)-858-699-3322
(+1)-858-876-1948 info@accelachem.com United States 19969 58
Hubei xin bonus chemical co. LTD
86-13657291602
027-59338440 linda@hubeijusheng.com CHINA 23035 58
Shandong chuangyingchemical Co., Ltd.
18853181302
sale@chuangyingchem.com CHINA 5917 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 37282 58
Alchem Pharmtech,Inc.
8485655694
sales@alchempharmtech.com United States 63726 58
Wuhan Chemwish Technology Co., Ltd
027-67849912
sales@chemwish.com CHINA 10829 58

View Lastest Price from 4-Fluorobenzoic acid manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-10-15 4-Fluorobenzoic acid
456-22-4
US $15.00 / KG 1KG 99% 300MT/year Speranza Chemical Co., Ltd.
2021-10-12 4-fluorobenzoic acid
456-22-4
US $52.00 / Kg/Bag 25Kg/Bag 99.99% 200ton Hebei Mojin Biotechnology Co., Ltd
2021-07-20 4-Fluorobenzoic acid
456-22-4
US $0.10 / KG 0.1KG 98% 200TONS Shaanxi Dideu Medichem Co. Ltd

4-Fluorobenzoic acid Spectrum


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