ChemicalBook >> CAS DataBase List >>METHIOTHEPIN MALEATE
METHIOTHEPIN MALEATE
- CAS No.
- 19728-88-2
- Chemical Name:
- METHIOTHEPIN MALEATE
- Synonyms
- RO 8-6837;metitepinmaleate;Metitepine maleate;METHIOTHEPIN MALEATE;f)thiepin,10,11-dihydro-8-methylthio-10-(4-methylpiperazino)-dibenzo(hyd;f)thiepin,10,11-dihydro-10-(4-methylpiperazino)-8-methylthio-dibenzo(hyd;1-(10,11-dihydro-8-methylthiodibenzo(b,f)thiepin-10-yl)-4-methyl-piperazin;8-methylthio-10-(4-methylpiperazino)-10,11-dihydrodibenzo(b,f)thiepinmaleate;1-[10,11-DIHYDRO-8-(METHYLTHIO)DIBENZO[B,F]THIEPIN-10-YL]-4-METHYLPIPERAZINE MALEATE;1-Methyl-4-(8-(methylthio)-10,11-dihydrodibenzo[b,f]thiepin-10-yl)piperazine maleate
- CBNumber:
- CB2181680
- Molecular Formula:
- C24H28N2O4S2
- Molecular Weight:
- 472.62
- MDL Number:
- MFCD00209930
- MOL File:
- 19728-88-2.mol
Last updated:2023-06-08 09:03:09
| Melting point | 171-173° |
|---|---|
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | Soluble to 100 mM in DMSO |
| form | Powder |
| FDA UNII | LVP2XBC3GA |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301+H311+H331-H402 | |||||||||
| Precautionary statements | P261-P264-P270-P271-P273-P280-P301+P310-P321-P330-P302+P352-P304+P340-P311-P312-P361+P364-P403+P233-P405-P501 | |||||||||
| Toxicity | LD5O in mice (mg/kg): 51 i.v.; 94 orally (Jilek) | |||||||||
| NFPA 704 |
|
METHIOTHEPIN MALEATE price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 23138 | Methiothepin (maleate) ≥98% | 19728-88-2 | 10mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 23138 | Methiothepin (maleate) ≥98% | 19728-88-2 | 25mg | $70 | 2024-03-01 | Buy |
| Cayman Chemical | 23138 | Methiothepin (maleate) ≥98% | 19728-88-2 | 50mg | $100 | 2024-03-01 | Buy |
| Cayman Chemical | 23138 | Methiothepin (maleate) ≥98% | 19728-88-2 | 100mg | $184 | 2024-03-01 | Buy |
| TRC | M260625 | MethiothepinMaleate | 19728-88-2 | 50mg | $140 | 2021-12-16 | Buy |
METHIOTHEPIN MALEATE Chemical Properties,Uses,Production
Uses
Methiothepin Maleate exhibits anticonvulsant property and it is able to suppress pentylenetetrazol induced fos expression in zebrafish. In addition, Methiothepin Maleate is a 5-HT antagonist.
Uses
Biochemical tool in serotonin receptor binding studies.
Definition
ChEBI: A maleate salt obtained by reaction of methiothepin with one equivalent of maleic acid. Potent 5-HT2 antagonist, also active as 5-HT1 antagonist. Differentiates 5-HT1D sub-types. Also displays ffinity for rodent 5-HT5B, 5-HT5A, 5-HT7 and 5-HT6 receptors (pK1 values are 6.6, 7.0, 8.4 and 8.7 respectively).
METHIOTHEPIN MALEATE Preparation Products And Raw materials
Raw materials
Preparation Products
METHIOTHEPIN MALEATE Suppliers
Global( 18)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42057 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44894 | 58 |
| Changzhou Furuisi Biotechnology Co., Ltd | 0519-85524369 | 3477467573@qq.com | China | 8618 | 58 |
19728-88-2(METHIOTHEPIN MALEATE)Related Search:
RO 8-6837
1-(10,11-dihydro-8-methylthiodibenzo(b,f)thiepin-10-yl)-4-methyl-piperazin
8-methylthio-10-(4-methylpiperazino)-10,11-dihydrodibenzo(b,f)thiepinmaleate
f)thiepin,10,11-dihydro-10-(4-methylpiperazino)-8-methylthio-dibenzo(hyd
f)thiepin,10,11-dihydro-8-methylthio-10-(4-methylpiperazino)-dibenzo(hyd
metitepinmaleate
Dibenzo(B,F)thiepin, 10,11-dihydro-10-(4-methylpiperazino)-8-methylthio-, hydrogen maleate
Dibenzo(B,F)thiepin, 10,11-dihydro-8-methylthio-10-(4-methylpiperazino)-, hydrogen maleate
Metitepine maleate
Piperazine, 1-(10,11-dihydro-8-methylthiodibenzo(B,F)thiepin-10-yl)-4-methyl-, maleate (1:1)
1-[10,11-DIHYDRO-8-(METHYLTHIO)DIBENZO[B,F]THIEPIN-10-YL]-4-METHYLPIPERAZINE MALEATE
METHIOTHEPIN MALEATE
Piperazine, 1-[10,11-dihydro-8-(methylthio)dibenzo[b,f]thiepin-10-yl]-4-methyl-, (2Z)-2-butenedioate (1:1)
1-Methyl-4-(8-(methylthio)-10,11-dihydrodibenzo[b,f]thiepin-10-yl)piperazine maleate
19728-88-2