ChemicalBook >> CAS DataBase List >>1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent

1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent

1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent structure

CAS No.: 887144-97-0

Chemical Name:: 1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent

Synonyms: Togni Reagent;togni's reagent;togni's reagent;3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole;1-Trifluoromethyl-3,3-dimethyl-1,2-benziodoxole;3,3-DMethyl-1-(trifluoroMethyl)-1,2-benziodoxole;3,3-Dimethyl-1-(trifluoromethyl)-1,2-benzodioxole;1,3-Dihydro-3,3-diMethyl-1-(trifluoroMethyl)-1,2-b;1,2-Benziodoxole,3,3-dimethyl-1-(trifluoromethyl)-;3,3-dimethyl-1-(trifluoromethyl)-1λ3,2-benziodoxole

CBNumber:: CB22101080

Molecular Formula:: C10H10F3IO

Molecular Weight:: 330.09

MDL Number:: MFCD10567056

MOL File:: 887144-97-0.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 00:01:59

Product description	Number	Pack Size	Price
3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole 95%	696641	1g	$486
3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole 95%	696641	5g	$938
1-Trifluoromethyl-3,3-dimethyl-1,2-benziodoxole >97.0%(HPLC)	T2624	1g	$181
1-Trifluoromethyl-3,3-dimethyl-1,2-benziodoxole >97.0%(HPLC)	T2624	5g	$590
3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole ≥98%(NMR)	36165	100MG	$64.9
More product size

Request For Quotation

1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent Properties

Melting point	75-79 °C
storage temp.	2-8°C
solubility	Chloroform (Slightly), Methanol (Slightly)
form	powder
color	white to off-white
Stability	Moisture Sensitive
InChI	InChI=1S/C10H10F3IO/c1-9(2)7-5-3-4-6-8(7)14(15-9)10(11,12)13/h3-6H,1-2H3
InChIKey	HVAPLSNCVYXFDQ-UHFFFAOYSA-N
SMILES	I1(C(F)(F)F)C2=CC=CC=C2C(C)(C)O1
FDA UNII	3OK0E02MT6
UNSPSC Code	12352101
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02,GHS07

Signal word

Warning

Hazard statements

H228-H315-H319-H335

Precautionary statements

P210-P302+P352-P305+P351+P338

target organs

Respiratory system

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36/37

RIDADR

1325

WGK Germany

TSCA

HazardClass

4.1

PackingGroup

Ⅲ

HS Code

29349990

Storage Class

4.1B - Flammable solid hazardous materials

Hazard Classifications

Eye Irrit. 2
Flam. Sol. 2
Skin Irrit. 2
STOT SE 3

NFPA 704

	0
2		0

1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent price More Price(43)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	696641	3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole 95%	887144-97-0	1g	$486	2026-04-30	Buy
Sigma-Aldrich	696641	3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole 95%	887144-97-0	5g	$938	2026-04-30	Buy
TCI Chemical	T2624	1-Trifluoromethyl-3,3-dimethyl-1,2-benziodoxole >97.0%(HPLC)	887144-97-0	1g	$181	2026-04-30	Buy
TCI Chemical	T2624	1-Trifluoromethyl-3,3-dimethyl-1,2-benziodoxole >97.0%(HPLC)	887144-97-0	5g	$590	2026-04-30	Buy
Chem-Impex	36165	3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole ≥98%(NMR)	887144-97-0	100MG	$64.9	2026-05-19	Buy

Product number	Packaging	Price	Buy
696641	1g	$486	Buy
696641	5g	$938	Buy
T2624	1g	$181	Buy
T2624	5g	$590	Buy
36165	100MG	$64.9	Buy

1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent Chemical Properties,Uses,Production

Description

1,3-dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole is in the form of colorless, white solid. It is soluble in all common organic solvents. It is used as effective and very versatile reagent for trifluoromethylation reactions of a variety of compounds including secondary and primary aryland alkylphospines, phenols, peptides containing cysteine residues by SPPS and electrophilic S-trifluoromethylation, arenes and N-heterocycles, and electrophilic N-trifluoromethylation of arozoles.

Reference

J. Charpentier, N. Früh, A. Togni, Electrophilic Trifluoromethylation by use of hypervalent iodine reagents, Chemical Reviews, 2015, vol. 115, pp. 650-682

Chemical Properties

White to light yellow solid

Uses

Togni’s Reagent is used in trifluoromethylation reactions.

Uses

Mild, electrophilic, hypervalent iodine CF3 reagent effective for the trifluoromethylation of a wide range of substrates.

reaction suitability

reaction type: C-C Bond Formation

1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent synthesis

Synthesis of 1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent from Methyl 2-iodobenzoate

1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent Preparation Products And Raw materials

Raw materials

1,2-Benziodoxole, 1-(acetyloxy)-1,3-dihydro-3,3-dimethyl 1-Fluoro-3,3-dimethyl-1,2-benziodoxole 1-Chloro-1,3-dihydro-3,3-diMethyl-1,2-benziodoxole Methyl 2-iodobenzoate 2-(2-iodophenyl)propan-2-ol

Preparation Products

1-Bromo-4-(1-trifluoromethyl-cyclopropyl)-benzene 3-(trifluoroMethyl)pyrazin-2-aMine 4-(TRIFLUOROMETHYL)DIPHENYL ETHER 4-(tert-Butyl)-alpha,alpha,alpha-trifluorotoluene, 1-(tert-Butyl)-4-(trifluoromethyl)benzene 2-[(trifluoromethyl)sulfanyl]phenol

1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent Suppliers

Global( 175)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	+86-13017695106 +86-13676922317	jiuyitime@fdachem.com	China	16513	58
Springchem New Material Technology Co.,Limited	+86-021-62885108 +8613917661608	info@spring-chem.com	China	2068	57
Capot Chemical Co.,Ltd.	+8613336195806	sales@capot.com	China	29640	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21587	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29815	58
Changzhou Ansciep Chemical Co., Ltd.	+86 519 86305871	sales@ansciepchem.com	CHINA	4241	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
Richest Group Ltd	18017061086	oled@richest-group.com	CHINA	5600	58
Fuxin Pharmaceutical	+86-021-021-50872116 +8613122107989	contact@fuxinpharm.com	China	10000	58

Supplier	Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	58
Springchem New Material Technology Co.,Limited	57
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Changzhou Ansciep Chemical Co., Ltd.	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Richest Group Ltd	58
Fuxin Pharmaceutical	58

View Lastest Price from 1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-04-17	Togni's Reagent 887144-97-0	$1.60-6.60	1kg	99%	100kg	ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
2025-12-01	1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent 887144-97-0		1kg	99%	10000KGS	Shaanxi Dideu New Materials Co. Ltd
2025-12-01	1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent 887144-97-0		1kg	99%	10000KGS	Shaanxi Dideu New Materials Co. Ltd

Togni's Reagent
887144-97-0
$1.60-6.60
99%
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent
887144-97-0
$0.00
99%
Shaanxi Dideu New Materials Co. Ltd

1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent
887144-97-0
$0.00
99%
Shaanxi Dideu New Materials Co. Ltd

1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent Spectrum

1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent(887144-97-0)¹HNMR 1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent(887144-97-0)FT-IR

887144-97-0(1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent)Related Search:

(Difluoromethyl)bis(2,5-dimethylphenyl)sulfonium Tetrafluoroborate 1-TrifluoroMethyl-1,2-benziodoxol-3(1H)-one (PERFLUORO-N-HEXYL)PHENYLIODONIUM TRIFLUOROMETHANESULFONATE Pyrazine Lactic acid

N,N-Dimethylacetamide N,N-Dimethylaniline Diphenyl(trifluoromethyl)sulfonium trifluoromethanesulfonate 2,2,2-trifluoroethyl(phenyl)iodonium trifluoromethanesulfonate diphenyl(2,2,2-trifluoroethyl)sulfanium trifluoromethanesulfonate

(perfluoroethyl)diphenylsulfonium trifluoromethanesulfonate Mesityl(2,2,2-trifluoroethyl)iodonium trifluoromethanesulfonate (difluoromethyl)(2,4-dimethylphenyl)(phenyl)sulfonium tetrafluoroborate Iodonium, (1,1,2,2,3,3,4,4,4-nonafluorobutyl)phenyl-,1,1,1-trifluoromethanesulfonate (2,2-difluoroethyl)diphenylsulfonium trifluoromethanesulfonate

2-IODOISOPROPYLBENZENE Trifluoromethyl iodide 1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent

1of4

1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent 1,3-dihydro-3,3-diMethyl-1-(trifluoroMethyl)-1,2-benziodoxole 1,3-Dhydro-3,3-diMethyl-1-(trifluoroMethyl)-1,2-benziodoxole 3,3-DMethyl-1-(trifluoroMethyl)-1,2-benziodoxole 1,3-Dihydro-3,3-diMethyl-1-(trifluoroMethyl)-1,2-b 3,3-DiMethyl-1-(trifluoroMethyl)-1,2-benziodoxole 95% 3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole / TOGNI A 3,3-DiMethyl-1-(trifluoroMethyl)-1,2-benziodoxole (Togni‘s reagent) 3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, >=98% 3,3-Dimethyl-1-(trifluoromethyl)-1,2- benziodoxole (Togni's reagent I) 3,3-Dimethyl-1-(trifluoromethyl)-1,2-benzodioxole 1,2-Benziodoxole,3,3-dimethyl-1-(trifluoromethyl)- 1-Trifluoromethyl-3,3-dimethyl-1,2-benziodoxole, 97%, for synthesis 3,3-dimethyl-1-(trifluoromethyl)-1$l^{3},2-benziodoxole 3,3-dimethyl-1-(trifluoromethyl)-1λ3,2-benziodoxole Togni`s Reagent (3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole) extrapure, 97% 3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole (ACI) 3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole - [D52498] 1-Trifluoromethyl-3,3-dimethyl-1,2-benziodoxole 3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole togni's reagent togni's reagent Togni Reagent 887144-97-0 C10H10F3IO